Evaluating solar power plant sites using integrated GIS and MCDM methods: a case study in Kermanshah Province.

This study utilizes an integrated Geographic Information System (GIS)-based Multi-Criteria Decision-Making (MCDM) approach to perform Solar Power Plant Site Selection (SPPSS) in Kermanshah Province, Iran. It introduces a novel group weighting method, the Dempster-based Best-Worst Method (DBWM), which combines weights vectors derived from experts' opinions. The study also conducts a comprehensive sensitivity analysis comparing four GIS-based models for SPPSS.

Association of dietary acid load with inflammatory markers, oxidative stress, and clinical features in patients with knee osteoarthritis.

Knee osteoarthritis (KOA) is a prevalent chronic condition characterized by inflammation and oxidative stress, particularly in individuals over 40. Dietary factors, specifically dietary acid load (DAL), may influence these pathological processes. However, the relationship between DAL and inflammatory markers, oxidative stress, and clinical features in patients with KOA remains unexplored.

Interactions between DASH-style diet and ADIPOQ and ARL15 genes polymorphisms on blood pressure and central obesity in Iranian adults.

This study aimed to investigate the interactions between the Dietary approaches to stop hypertension (DASH) and the rs1501299 and rs6450176 SNPs in terms of cardiometabolic risk factors. This cross-sectional study was conducted on 387 adults (20-70 years old) residing in Yazd, Iran. The participants were selected from participants in the recruitment phase of the Yazd Health Study (YaHS) which is a population-based cohort of 9,962 adults.

A dynamic co-expression approach reveals Gins2 as a potential upstream modulator of HNSCC metastasis.

Head and neck squamous cell carcinoma (HNSCC) is an aggressive cancer that is notably associated with a high risk of lymph node metastasis, a major cause of cancer mortality. Current therapeutic options remain limited to surgery supplemented by radio- or chemotherapy; however, these interventions often result in high-grade toxicities. Distant metastasis significantly contributed to the poor prognosis and decreased survival rates.

Induction of IMPDH-Based Cytoophidia by a Probable IMP-Dependent ARL13B-IMPDH Interaction.

Inosine Monophosphate Dehydrogenase (IMPDH) catalyzes rate-limiting step of the reaction converting inosine monophosphate (IMP) to guanine nucleotides. IMPDH is up-regulated in the healthy proliferating cells and also in tumor cells to meet their elevated demand for guanine nucleotides. An exclusive regulatory mechanism for this enzyme is filamentation, through which IMPDH can resist allosteric inhibition by the end product, GTP.

Opioid reward and deep brain stimulation of the lateral hypothalamic area.

Opioid use disorder (OUD) is considered a global health issue that affects various aspects of patients' lives and poses a considerable burden on society. Due to the high prevalence of remissions and relapses, novel therapeutic approaches are required to manage OUD. Deep brain stimulation (DBS) is one of the most promising clinical breakthroughs in translational neuroscience.

Investigating the role of lifestyle, knowledge and health beliefs in performing preventive behaviours against human papilloma virus in married women.

Objectives: The aim of this research was investigating the role of lifestyle, knowledge and health beliefs in performing preventive behaviours against HPV in married women.

Background: Human Papilloma Virus (HPV) is a significant public health concern in Iran, with a relatively high prevalence in the general female population.

Methods: The study utilized a cross-sectional survey among 260 married women working at the university.

Sex steroid disrupting effects of nonsteroidal anti-inflammatory drugs on the Persian Gulf Arabian Sea bream, Acanthopagrus arabicus: In vitro model of environmental drug contamination.

The presence of pharmaceuticals in aquatic ecosystems and their impact on humans and the environment are growing concerns in environmental health. This study aimed to evaluate the potential reproductive effects of diclofenac, ibuprofen, and aspirin on dissociated ovarian and testicular cells from Arabian Sea bream, Acanthopagrus arabicus. The cells were exposed to varying concentrations of the pharmaceuticals for 48 h.

The double-edged sword role of natural Killer cells in Parkinson's disease.

Neurological disorders are the leading cause of disability worldwide, with Parkinson's disease (PD) emerging as a rapidly growing neurological condition on a global scale. Although treatments exist to alleviate symptoms and maintain patients' quality of life, PD remains incurable. According to some recent studies, natural killer (NK) cells may play a role in clearing alpha-synuclein aggregates, which are the main component of Lewy bodies that cause neuronal degeneration in Parkinson's disease.

A rare presentation of angiolymphoid hyperplasia with eosinophilia (ALHE) on the cheek: Case report and two-year follow-up.

Introduction And Importance: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare benign vascular tumor characterized by abnormal endothelial proliferation and inflammatory cell infiltration, primarily affecting the head and neck region. The diverse clinical presentations of ALHE pose significant diagnostic challenges, often leading to misdiagnosis. Accurate histopathological examination is crucial for differentiating ALHE from other vascular lesions and guiding appropriate treatment.

Management of nasopharyngeal stenosis post-tonsillectomy using the Madame Butterfly technique: A case report with novel approach.

Background: Nasopharyngeal stenosis (NPS) is an uncommon but significant complication that arise following tonsillectomy in adults, leading to manifestations including obstructive sleep apnea and dysphagia. This condition is often rare, underscoring the need for awareness and effective management strategies.

Case Presentation: We present a case involving a 48-year-old female who developed nasopharyngeal stenosis (NPS) 15 months after undergoing a tonsillectomy.

Acceleration of bone healing by a growth factor-releasing allo-hybrid graft.

Introduction: Human amniotic membrane (hAM) has a highly biocompatible natural scaffold that is abundant in several extracellular matrix (ECM) components, including but not limited to platelet-derived growth factor (PDGF), transforming growth factor (TGF), and fibroblast growth factor (FGF). In our study, we have focused on a mixture of hAM and demineralized bone matrix (DBM) as an allo-hybrid graft to deliver it into the site of bone defect to decrease bone remodeling time.

Methods: Allo-hybrid grafts were prepared by coating the jelly made of decellularized and lyophilized hAM (AMJ) on the surface of DBM and subsequently underwent in vitro studies, such as alkaline phosphatase activity, MTT assay, and SEM analysis.

Optical assessment of heroin using laser-induced fluorescence spectroscopy based on modified Beer-Lambert formalism.

Heroin as a derivative of morphine contains the alkaloids and flavonoids with plenty of three to five aromatic rings. The latter is known as the main source of fluorescence emission after laser excitation. Here, laser induced fluorescence (LIF) spectroscopy at excitation line of 405 nm with the solvent densitometry method is introduced based on modified Beer-Lambert (MBL), for the rapid and reliable identification of street heroin samples.

A comparative life cycle analysis of bioremediation approaches for old-aged petroleum pollution in hypersaline soil.

Soil oil pollution is a major environmental issue, especially in oil-producing nations, as it threatens the health of plants, animals, and humans. While bioremediation has been extensively utilized as a cost-effective method for restoring oil-contaminated soil, its environmental impact has garnered relatively little attention. Researchers often concentrate on reducing pollutant concentrations below permissible limits to restore soil quality.

Evaluating convalescent plasma therapy in severe COVID-19: a retrospective cohort study.

Introduction: Convalescent plasma (CP) therapy is a form of passive immunization which has been used as a treatment for coronavirus disease 2019 (COVID-19). This study aims to evaluate the efficacy and safety of CP therapy in patients with severe COVID-19.

Methodology: In this retrospective cohort study, 50 patients with severe COVID-19 treated with CP at Shahid Beheshti Hospital, Kashan, in 2019 were evaluated.

Effectiveness of levamisole in the treatment of patients with severe COVID-19: a randomized controlled clinical trial.

Introduction: Inflammation plays a role in coronavirus disease 2019 (COVID-19) pathophysiology and anti-inflammatory drugs may help reduce the disease severity. Levamisole is an anthelmintic drug with immunomodulatory and possible antiviral effects. This study aimed to evaluate the role of levamisole in the treatment of patients with COVID-19.

Assessment of the validity and reliability of the nurses' professional values scale-revised in Persian version among nursing students.

Background: Evaluating professional values is crucial to developing effective strategies for integrating them into professional performance and clinical education. A standard questionnaire is an instrument that can be used to evaluate professional values. This study aimed to assess the validity and reliability of the Nurses Professional Values Scale-Revised (NPVS-R) among nursing students in the Persian language.

High-throughput phenotyping of wheat root angle and coleoptile length at different temperatures using 3D-printed equipment.

Background: Innovation in crop establishment is crucial for wheat productivity in drought-prone climates. Seedling establishment, the first stage of crop productivity, relies heavily on root and coleoptile system architecture for effective soil water and nutrient acquisition, particularly in regions practicing deep planting. Root phenotyping methods that quickly determine coleoptile lengths are vital for breeding studies.

Temporary ectopic banking as a treatment option for mangled thumb: a case report.

Background: Management of the extensive soft tissue injuries remains a significant challenge in orthopedic and plastic reconstructive surgery. Since the thumb is responsible for 40% of the functions of the hand, saving and reconstructing a mangled thumb is essential for the patient's future.

Case Presentation: This case report describes the management of a severe occupational thumb injury in a 25-year-old white Persian male who sustained an occupational injury to his left thumb, resulting in extensive burn, crush injury to the distal and proximal phalanx, and severe soft tissue damage to the first metacarpal, thenar, and palmar areas.

Diagnosis of lung cancer using salivary miRNAs expression and clinical characteristics.

Objective: Lung cancer (LC), the primary cause for cancer-related death globally is a diverse illness with various characteristics. Saliva is a readily available biofluid and a rich source of miRNA. It can be collected non-invasively as well as transported and stored easily.

Fluoride-induced testicular and ovarian toxicity: evidence from animal studies.

Fluoride (F), as a natural element found in a wide range of sources such as water and certain foods, has been proven to be beneficial in preventing dental caries, but concerns have been raised regarding its potential deleterious effects on overall health. Sodium fluoride (NaF), another form of F, has the ability to accumulate in reproductive organs and interfere with hormonal regulation and oxidative stress pathways, contributing to reproductive toxicity. While the exact mechanisms of F-induced reproductive toxicity are not fully understood, this review aims to elucidate the mechanisms involved in testicular and ovarian injury.

Identification of novel cytoskeleton protein involved in spermatogenic cells and sertoli cells of non-obstructive azoospermia based on microarray and bioinformatics analysis.

Background: During mammalian spermatogenesis, the cytoskeleton system plays a significant role in morphological changes. Male infertility such as non-obstructive azoospermia (NOA) might be explained by studies of the cytoskeletal system during spermatogenesis.

Methods: The cytoskeleton, scaffold, and actin-binding genes were analyzed by microarray and bioinformatics (771 spermatogenic cellsgenes and 774 Sertoli cell genes).

Prioritizing implementation solutions for the urban family physician policy in Iran: a multi-criteria decision-making study.

Background: Family physician program is one of the effective reforms of the health system in Iran, but despite the implementation of this program in rural areas and the passage of ten years since its implementation in two provinces of Fars and Mazandaran, its implementation has faced problems. The aim of this study is to identify and prioritize implementation solutions related to the challenges of the family physician program in Iran.

Methods: This is a qualitative study using semi-structured interviews with 22 snowball-sampled experts and managers of basic health insurers to extract problems and executive solutions through coding and data analysis using Atlas Ti software and content analysis in the first stage.

Evaluation of nutritional, anthropometric, and psychological outcomes in different metabolic and bariatric surgery techniques: a follow up study.

Background: Metabolic and bariatric surgery (MBS) is a suitable solution for the treatment of morbid obesity. Investigating an MBS method that has the best outcomes has always been the main concern of physicians. The current study aimed to compare nutritional, anthropometric, and psychological complications of individuals undergoing various MBS Techniques.

The relationship between intrinsic capacity and functional ability in older adults.

Introduction: Intrinsic Capacity in integrated geriatric care emphasizes the importance of a thorough functional assessment. Monitoring the intrinsic capacity of older individuals provides standardized and reliable information to prevent early disability. This study assessed the relationship between intrinsic capacity and functional ability in older adults.