299,984 results match your criteria: "Iran; and ¶Harvard Medical School[Affiliation]"

Vitiligo is a chronic depigmenting condition that causes amelanotic macules and patches on the skin. Despite various treatment options, treating vitiligo is a challenge. This study aimed to evaluate the combination of laser CO fractional and narrow-band ultraviolet B (NB-UVB) versus NB-UVB monotherapy in vitiligo patients.

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In this paper, a multilayer monopulse antenna at Ku-Band with high efficiency, high power handling capability, high gain, 45° linear polarization and low sidelobe is presented. A new slot antenna is proposed as a radiating element based on a cavity-backed slot-coupled patch antenna. Using an enclosed cavity structure reduces coupling between antenna elements, thus increasing the antenna efficiency.

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Low fertility in cows leads to early removal from herds. Since reproductive traits are complex and have low heritability, genetic analysis can aid in improving reproduction. This study identified key genes linked to fertility by conducting genome- and transcriptome-wide association studies, RNA-seq analysis, meta-analysis, weighted gene co-expression network analysis, and functional enrichment analysis.

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Parameter study of a 5G array antenna at 28 GHz.

Sci Rep

January 2025

Department of Electrical Engineering, Bushehr Branch, Islamic Azad University, Bushehr, Iran.

In this paper a 5G compact antenna is investigated at 28 GHz. The structure is based on Quasi-Yagi antenna comprising a director, driver, and reflector. The SIW technology is utilized to feed the antenna because of its numerous benefits.

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Objectives: The main objective was to evaluate the cost-effectiveness of various medical therapy combinations in managing chronic coronary syndrome (CCS) in Iran, based on real-world and patient-level data.

Design: A cost-utility analysis employing a Markov model was conducted using data from a retrospective cohort study.

Setting: The study was conducted in the healthcare setting of Iran, focusing on primary and secondary care.

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Introduction: To evaluate the short- and long-term clinical and financial outcomes of apheresis in COVID-19 survivors after hospital discharge.

Methods: Intensive care unit-discharged patients were followed for 6 months. Vital signs, laboratory markers, quality of life, and direct medical costs were analyzed to calculate incremental cost-effectiveness ratios (ICER) and to plot cost-effectiveness planes and acceptability curves.

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The catalytic performance of Candida antarctica lipase B (CALB) immobilized on silica-coated magnetic nanoparticles was evaluated for biodiesel production via methanolysis of rapeseed oil. Two different covalent immobilization approaches were compared to assess the effect of immobilization protocols on lipase efficiency. The first approach involved immobilization of CALB on amine-functionalized magnetic nanoparticles (MNPs), which targeted the Lys-rich regions of the enzyme.

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Effects of Resistance Training on Muscular Adaptations and Inflammatory Markers in Overweight and Obese Men.

Med Sci Sports Exerc

November 2024

Université Clermont Auvergne, CNRS, LaPSCo, Physiological and Psychosocial Stress, CHU Clermont-Ferrand, University Hospital of Clermont-Ferrand, Preventive and Occupational Medicine, Witty Fit, Clermont-Ferrand, FRANCE.

Purpose: Obesity may blunt exercise responsiveness to improve muscular adaptations. The effect of resistance training (RT) targeting different body regions on muscle and inflammatory markers is unclear. This study aimed to investigate the impact of upper (upper body exercises), lower (lower body exercises), or combined (upper body + lower body exercises) RT on muscle and inflammatory markers, body composition, and performance in overweight and obese men.

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Selection of combination adjuvants for enhanced immunogenicity of a recombinant CelTOS vaccine against Plasmodium falciparum.

Biochem Biophys Res Commun

January 2025

Malaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran, Tehran, Iran. Electronic address:

Recently, there has been significant interest in developing combination adjuvants to achieve efficient vaccines. However, it remains uncertain which combinations of adjuvants could best enhance the immune response to the recombinant antigen. In the current study, to improve the immunogenicity of Plasmodium falciparum cell traversal protein for ookinetes and sporozoites (PfCelTOS), we tested three different adjuvants: MPL, Poly I:C, and QS-21 alone or in a triple mixture (MPL/Poly I:C/QS-21; MPQ) and a dual mixture (Poly I:C/QS-21; PQ).

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Borophene based quasi planar nanocluster for ethanol, isobutanol, and acetone sensing: A first principle study.

J Mol Graph Model

January 2025

Department of Chemistry Education, Farhangian University, P.O. Box 14665-889, Tehran, Iran. Electronic address:

In this study, the need for efficient detection of volatile organic compounds (VOCs) in environmental monitoring, industrial safety, is addressed by investigating borophene-based B36 nanoclusters as gas sensors. Density functional theory (DFT) calculations were employed to examine the adsorption behavior of ethanol, isobutanol, and acetone on B surfaces, with a focus on vibrational modes, reactivity, and adsorption energies. It was found that acetone exhibits the strongest interaction with pristine B, indicating its potential for robust sensing applications.

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Purpose: This study aims to systematically evaluate all radionuclides used in knee RSV to date and identify the most suitable radionuclide for knee RSV.

Methods: To compare knee RSV with Y-90, P-32, Ho-166, Re-188, Au-198, Lu-177, Sm-153, and Re-186, we measured the radiation dose to non-target organs and the inducing of secondary malignancies in knee RSV patient, the radiation dose to family member and medical staff from the knee RSV patients, and the quality of post-treatment images.

Results: The Lifetime Attributable Risks of cancer incidence and mortality and the Relative Risks of solid cancer incidence and mortality are significantly higher for Y-90 and P-32 in both adult and pediatric patients compared to other radionuclides used in knee RSV.

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Objective: Research and tools are necessary for understanding prostate cancer biology. 3D cell culture models have been created to overcome the limitations of animal models and 2D cell culture. The amniotic membrane (AM), a natural biomaterial, emerges as an ideal scaffold for 3D cultures due to its accessibility and incorporation of the extracellular matrix (ECM) in both solid and liquid forms.

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Purpose: Health anxiety (HA) is a critical issue for cancer patients. This study investigates the role of intolerance of uncertainty (IU) in HA among a heterogeneous sample of cancer patients, comparing those with hematological malignancies and solid tumor cancers. It also explores the impact of demographic and cancer-related factors on HA.

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Cutaneous leishmaniasis (CL) is a tropical disease that can cause chronic lesions and leave life-long scars, leading to social stigmatization and psychological disorders. Using growth factors and immunomodulatory agents that could accelerate wound healing and reduce the scar is highly demanded. Epidermal growth factor (EGF) plays an essential role in wound healing.

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The brain can remarkably adapt its decision-making process to suit the dynamic environment and diverse aims and demands. The brain's flexibility can be classified into three categories: flexibility in choosing solutions, decision policies, and actions. We employ two experiments to explore flexibility in decision policy: a visual object categorization task and an auditory object categorization task.

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This paper focuses on modeling Resistor-Inductor (RL) electric circuits using a fractional Riccati initial value problem (IVP) framework. Conventional models frequently neglect the complex dynamics and memory effects intrinsic to actual RL circuits. This study aims to develop a more precise representation using a fractional-order Riccati model.

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5-FU is a widely used chemotherapy drug for esophageal carcinomas, but therapy failure has been observed in 5-FU-resistant patients. Overcoming this resistance is a significant challenge in cancer treatment, requiring identifying and targeting important resistance mechanisms. PYGO2 expression is crucial in developing resistance to various chemotherapy drugs.

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Ideal mentolabial sulcus depth in long-face, short-face, and normal-face in female individuals.

Oral Maxillofac Surg

January 2025

Department of Restorative, School of Dentistry, Dental Research Center, Hamadan University of Medical Sciences, Pajouhesh Square, Hamadan, 6517838736, Iran.

Purpose: The harmony between the lips and the chin is an essential parameter in facial esthetics, and the mentolabial sulcus (MLS) represents the level of this harmony. This study aimed to assess the effect of MLS depth on facial profile attractiveness in long-face, short-face, and normal-face Iranian female individuals.

Methods: An observational study with a questionnaire was conducted, and a profile photograph of an Iranian female with class I occlusion was altered to create long-face, normal-face and short-face profiles with MLS depth ranging from 1 to 12 mm.

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The present investigation evaluated the potential impacts of morin, a natural flavonoid, against cardiovascular disorders. Since inception until September 2024, PubMed, Scopus, and Web of Science have been searched extensively. The process involved eliminating duplicate entries and conducting a systematic review of the remaining studies post-full-text screening.

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MiRNAs: main players of cancer drug resistance target ABC transporters.

Naunyn Schmiedebergs Arch Pharmacol

January 2025

Solid Tumor Research Center, Cellular and Molecular Medicine Research Institute, Urmia University of Medical Sciences, Urmia, Iran.

Chemotherapy remains the cornerstone of cancer treatment; however, its efficacy is frequently compromised by the development of chemoresistance. Multidrug resistance (MDR), characterized by the refractoriness of cancer cells to a wide array of chemotherapeutic agents, presents a significant barrier to achieving successful and sustained cancer remission. One critical factor contributing to this chemoresistance is the overexpression of ATP-binding cassette (ABC) transporters.

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Fe, Ni, and Cu doped ceria nanoparticles (CeNPs) were prepared with a simple and one-pot hydrothermal synthesis method. We investigated the chemiluminescence (CL) interaction between these NPs and rhodamine B (Rh B) and found that the highest CL intensity was related to the Rh B- Cu doped CeNPs. We assigned that to the higher catalytic property of Cu doped NPs compared to the others.

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Approaches for Analyzing the Relationship Between Spirituality and Health Using Measures Contaminated with Indicators of Mental and Social Health.

J Relig Health

January 2025

School of Psychology & Public Health, College of Science, Health & Engineering, La Trobe University, Victoria, 3086, Australia.

There has been concern raised in religion/spirituality (R/S) research about the use of measures of spirituality that are contaminated by indicators of mental and/or social health. Many of these scales are used widely in published studies examining associations with health, and yet many researchers and reviewers are not aware of contamination issues. We have previously cautioned researchers to be careful in their choice of religious/spirituality (R/S) measures (Koenig and Carey in J Relig Health, 63(5):3729-3743.

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A novel electrochemical aptasensor based on bimetallic zirconium and copper oxides embedded within mesoporous carbon (denoted as ZrOCuO@mC) was constructed to detect miRNA. The porous ZrOCuO@mC was created through the pyrolysis of bimetallic zirconium/copper-based metal-organic framework (ZrCu-MOF). The substantial surface area and high porosity of ZrOCuO@mC nanocomposite along with its robust affinity toward aptamer strands, facilitated the effective anchoring of aptamer strands on the ZrOCuO@mC-modified electrode surface.

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Purpose: Bone expansion is one of the quickest, simplest, and most reliable methods of alveolar ridge augmentation for implant placement. This systematic review is designed to investigate the outcomes of the bone expansion technique for horizontal ridge augmentation.

Methods: The protocol of study has been prospectively registered into PROSPERO (CRD42023414686).

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