Fluoride Exposure and Children's IQ Scores: A Systematic Review and Meta-Analysis.

Importance: Previous meta-analyses suggest that fluoride exposure is adversely associated with children's IQ scores. An individual's total fluoride exposure comes primarily from fluoride in drinking water, food, and beverages.

Objective: To perform a systematic review and meta-analysis of epidemiological studies investigating children's IQ scores and prenatal or postnatal fluoride exposure.

Study of the effect of zinc oxide, selenium, and silver nanoparticles on the expression level of oxidative stress-associated genes in ovarian cancer.

Reactive oxygen species (ROS) generated by oxidative stress have emerged as critical factors in the pathophysiology of malignancies. This study investigated the antioxidant and anticancer properties of zinc (Zn), selenium (Se), and silver (Ag) nanoparticles (NPs) against the A2780 human ovarian cancer cell line. Here, the bioinformatics approach was used to determine the top differentially expressed genes associated with oxidative stress.

Highly Selective and Sensitive Visual Detection of Fe using a Simple Quinazoline-Based Colorimetric Sensor.

Among the various cations, the Fe ion is one of the most critical transition metal ions in living cells for many cellular functions and enzymatic activities. The decrease or overloading of Fe can lead to different disruptions in humans. Also, Fe, highly toxic, is very common in all industrial wastewater.

[In]In-RM2: a high potential agent for SPECT imaging of GRPR-expressing tumors.

Gastrin-releasing peptide receptors (GRPRs) overexpressed in many cancers are known as promising biomarkers to target tumors such as prostate, breast, and lung cancers. As the early diagnosis of the cancers can serve for better treatment of the patients, [In]In-DOTA-Pip-D-Phe-Gln-Trp-Ala-Val-Gly-His-Sta-Leu-NH2 ([In]In-RM2) was prepared using an in-house developed Sn/In generator. 0.

Degradation of ciprofloxacin using CoFeO@three-dimensional TiO@graphene aerogels composite: kinetic, reusability, mineralization, degradation pathway, and toxicity assessment.

An investigation into the degradation of ciprofloxacin (CIP) under visible light was carried out using an efficient photocatalyst, i.e., CoFeO@3D-TiO@GA, synthesized by doping CoFeO@three-dimensional-TiO into a hierarchical porous graphene aerogel.

Aqueous and ethanolic extracts of Moringa oleifera leaves induce selective cytotoxicity in Raji and Jurkat cell lines by activating the P21 pathway independent of P53.

Background: The traditional use of Moringa oleifera (MO), an essential food source in Africa and Asia, to cure various diseases dates back thousands of years. This study examines the aqueous and ethanolic leaf extracts of MO's in vitro anti-leukemia capabilities.

Methods: After preparing aqueous and ethanolic MO leaf extracts, cells were treated with various concentrations for 48 h.

Full analysis for the optical properties of the CsXInBr (X = Cu or Ag) double perovskites using both GW and Bethe-Salpeter approaches.

Context: Exploration for renewable and environmentally friendly energy sources has become a major challenge to overcome the depletion of fossil fuels and their environmental hazards. Therefore, solar cell technology, as an alternative solution, has attracted the interest of many researchers. In the present work, the CsXInBr (X = Cu or Ag) compounds as lead-free halide perovskites have been studied due to their direct energy gap in the range of solar energy, thermodynamic stability, low effective mass of electrons, and high absorption coefficient.

Fractional-order modeling of human behavior in infections: analysis using real data from Liberia.

This paper presents a fractional-order model using the Caputo differential operator to study Ebola Virus Disease (EVD) dynamics, calibrated with Liberian data. The model demonstrates improved accuracy over integer-order counterparts, particularly in capturing behavioral changes during outbreaks. Stability analysis, Lyapunov functions, and a validated numerical method strengthen its mathematical foundation.

A Comprehensive Insight into Apoptosis: Molecular Mechanisms, Signaling Pathways, and Modulating Therapeutics.

Apoptosis, or programmed cell death, is a fundamental biological process essential for maintaining tissue homeostasis. Dysregulation of apoptosis is implicated in a variety of diseases, including cancer, neurodegenerative disorders, and autoimmune conditions. This review provides an in-depth insight into the molecular mechanisms and signaling pathways that regulate apoptosis, highlighting both intrinsic and extrinsic pathways.

Confounders: A threat to the interpretation of research findings in endodontics.

Confounding is a significant challenge in endodontic research, as it can blur the true effect and relationship between exposure and outcomes, potentially compromising the internal validity of research findings. Confounding variables can create apparent differences between study groups when no actual difference exists or fail to reveal true differences when they are present. Additionally, confounding can lead to either an underestimation or an overestimation of the effect of exposure on the outcome.

Development of smart packaging halochromic films embedded with anthocyanin pigments; recent advances.

Nowadays, innovative biodegradable packaging based on pH-sensitive natural dyes is being developed. These smart systems quickly inform the food quality to the consumer and monitor fresh foods in real-time. Smart packaging protects food against ambiance risks and simultaneously sends information to users for variations and alterations in the packaging settings.

Diagnosis Osteoporosis Risk: Using Machine Learning Algorithms Among Fasa Adults Cohort Study (FACS).

Introduction: In Iran, the assessment of osteoporosis through tools like dual-energy X-ray absorptiometry poses significant challenges due to their high costs and limited availability, particularly in small cities and rural areas. Our objective was to employ a variety of machine learning (ML) techniques to evaluate the accuracy and precision of each method, with the aim of identifying the most accurate pattern for diagnosing the osteoporosis risks.

Methods: We analysed the data related to osteoporosis risk factors obtained from the Fasa Adults Cohort Study in eight ML methods, including logistic regression (LR), baseline LR, decision tree classifiers (DT), support vector classifiers (SVC), random forest classifiers (RF), linear discriminant analysis (LDA), K nearest neighbour classifiers (KNN) and extreme gradient boosting (XGB).

Drug Extravasation in a Tertiary Referral Children Hospital: A Prospective Cohort Study.

Extravasation injuries are prevalent in pediatric hospitals and often result in tissue damage and extended hospital stays. However, limited data exist regarding risk factors for extravasation in children. This study aimed to identify these risk factors in pediatric patients receiving intravenous (IV) therapy.

Molecular Characterization of Gene Encoding Outer Membrane Protein in Pathogenic Serovars in Iran.

The protein is highly conserved among pathogenic serovars and it is expressed during both acute and chronic infections. The aim of this study was to clone and sequence of the protein-encoding gene of serovars. In this study, 23 pathogenic serovars and two nonpathogenic serovars were used.

An economical synthesis of benzodiazepines using ACT@IRMOF core-shell as a potential eco-friendly catalyst through the activated carbon of thymus plant (ACT).

Here, a straightforward design is employed to synthesize a nanocatalyst based on a carbon-activated modified metal-organic framework using the solvothermal method. This work presents a simple and practical approach for producing the activated carbon derived from the Thymus plant (ACT) modified with amine-functionalized isoreticular metal-organic framework-3 (IRMOF-3) to create an ACT@IRMOF-3 core-shell structure. Successful functionalization was confirmed through N adsorption isotherms, FT-IR, FE-SEM, TEM, EDS, elemental mapping, TGA, and XRD analysis.

Evaluation of the Efficacy of Medicinal Plants in Treating Bacterial Vaginosis: A Comprehensive Systematic Review of Interventional Studies.

Background: Bacterial Vaginosis (BV) is the most prevalent cause of vaginal infection among women. This study aimed to summarize the evidence related to the effectiveness of medicinal plants as an alternative therapy for the management of BV.

Materials And Methods: PubMed, Scopus, Cochrane Library, Web of Science, and Medline PubMed were systematically searched.

Relationship between Cellphone Overuse with Sleep Quality and Self-efficacy in Clinical Performance of Nurse and Midwifery Students.

Background: Identification of the factors related to students' academic success and clinical self-efficacy plays a significant role in their ability to provide independent patient care. The present study was conducted to investigate the relationship of cell phone overuse with sleep quality and self-efficacy in the clinical performance of nursing and midwifery students.

Materials And Methods: This descriptive-correlational study was conducted on 211 nursing and midwifery students of Isfahan University of Medical Sciences in 2021-2022.

The Effects of Local Heating on Facilitating Radial Angiography: A Randomized Controlled Trial.

Background: Angiography through the radial artery is a novel selective approach with several advantages. Shortening the duration of each stage of the procedure leads to many benefits for patients and health personnel. This study aimed to investigate the effect of local forearm heating on facilitating radial angiography.

Comparison of Empathy with Patients between Surgical and Psychiatric Medical Residents.

Background: Empathy is considered paramount to the medical profession because it affects patients' satisfaction, compliance, and quality of care. It has been studied that medical residents in non-psychiatry specialties (especially general surgery) pay less attention to their patients' experiences and emotions. This study measured and compared surgical and psychiatric medical residents' empathy scores.

Health Information Disorders Models: A Scoping Review.

Background: The purpose of this scoping review is to identify the models of Health Information Disorders (HIDs), the components of these models, their study setting, and their designing approaches.

Materials And Methods: In this study, PubMed, Web Of Science (WOS), Scopus, ProQuest, and Embase databases were searched to identify relevant articles. After screening the identified studies, 22 studies were selected.

Comparison of Nurses' Workload and Multiple Organ Failure of Patients Hospitalized in the COVID-19 and Non-COVID-19 Intensive Care Units.

Background: Measuring nurses' workload and related factors in intensive care units and reviewing their staffing is very important during COVID-19. This study aims to compare nurses' workload and multiple organ failure of patients hospitalized during the COVID-19 in intensive care units and non-COVID-19 intensive care units.

Materials And Methods: An observational study was conducted with 768 patients hospitalized in intensive care units and Zanjan City (Iran) intensive care units in 2021.

Investigating Some Effective Factors on the Prediction of Continuous Positive Airway Pressure Failure Rate in COVID-19-Related Hypoxemia.

Background: Considering the importance of using Non-Invasive Ventilation (NIV) in COVID-19-related hypoxemia, the present study was conducted to determine the effective factors on Continuous Positive Airway Pressure (CPAP) failure rate in COVID-19-related hypoxemia.

Materials And Methods: This research was a retrospective cross-sectional study (2021) investigating the records of 200 adult patients with the medical diagnosis of acute respiratory failure (ARF) of COVID-19, admitted to the Intensive Care Unit (ICU) in Shoushtar (southwestern Iran) who underwent CPAP therapy. The Heart rate, Acidosis, Consciousness, Oxygenation, and Respiratory rate (HACOR) scores were measured before the treatment and 1 h after undergoing CPAP treatment.

The Relationship between Spiritual Intelligence and Fatigue and Moral Distress in Emergency Nurses: A Cross-Sectional Study.

Background: Emergency nurses face various challenging conditions and many moral distress that may associated with fatigue from providing care. The spiritual intelligence of nurses has been found to have an impact on the quality of care. This study aimed to investigate the relationship between the spiritual intelligence of emergency nurses with fatigue from providing care and moral distress in emergency nurses.

Electrocardiogram Interpretation Competency Among Emergency Nurses in Jordan: A Cross-Sectional Study.

Background: Electrocardiogram (ECG) is considered one of the most frequently carried out diagnostic tests in emergency rooms. To develop and refine the competencies of emergency nurses, it becomes imperative to assess the current level of knowledge and practice among nurses regarding ECG and other diagnostic tests. The study aimed to assess the ECG interpretation competency and its associated factors among emergency nurses in Jordan.

Evaluating the General Health Risk Factors (Physical, Psychological, and Social Functions) of Hospital Staff a Year after COVID-19 Outbreak in 2020-2021, Isfahan Iran.

Background: Healthcare workers are the first to be exposed to the virus and are at greater risk than the general public. This study aimed to examine the risk factors that affected hospital staff's general health during the COVID-19 pandemic in Isfahan, Iran.

Materials And Methods: This cross-sectional study was conducted on the staff of all hospitals in Isfahan one year after the COVID-19 outbreak (2021-2022).