Agronomic characteristics, mineral nutrient content, antioxidant capacity, biochemical composition, and fatty acid profile of Iranian pistachio (Pistacia vera L.) cultivars.

Background: Pistachio (Pistacia vera L.) nuts are among the most popular nuts. The pistachio cultivars are tolerant to both drought and salinity, which is why they are extensively grown in the arid, saline, and hot regions of the Middle East, Mediterranean countries, and the United States.

The effects of intermittent fasting on antioxidant and inflammatory markers and liver enzymes in postmenopausal, overweight and obese women with rheumatoid arthritis: a randomized controlled trial.

Rheumatoid arthritis (RA) is a chronic inflammatory disorder affecting postmenopausal women. This study investigated the effects of intermittent fasting (IF) on antioxidant and inflammatory markers and liver enzymes in postmenopausal, overweight and obese women with RA. This 8-week randomized controlled trial included 44 postmenopausal women with RA divided into an intervention group following a 16:8 IF diet and a control group maintaining their usual diet and received recommendations for healthy eating.

Investigating the effect of ceramic fiber on the mechanical properties of glassphalt.

Glassphalt suffers from performance defects, especially against moisture damage and fatigue cracking. In this research, the performance of glassphalt modified with CF has been evaluated against moisture damage, fatigue cracking and rutting. Based on this, Modified Lottman, Wilhelmy Plate (WP), Indirect Tensile Stiffness Modulus (ITSM), Indirect Tensile Fatigue (ITF), and Repeated Load Axial (RLA) tests have been performed on glassphalt modified with CF.

Comparing the effects of Mycozin and Clotrimazole 1% creams on vaginal candidiasis: a triple-blinded randomized controlled trial.

Clotrimazole 1% and Mycozin vaginal cream have been reported to be effective in relieving the symptoms of vulvovaginitis caused by Candida. The resistance to azole compounds, and the side effects of chemical drugs have been reported following azole therapy. It was hypothesized that Mycozin is at least as effective as Clotrimazole in treating vaginal candidiasis.

Designing a terahertz optical sensor based on helically twisted photonic crystal fiber for toxic gas sensing.

A novel helically twisted photonic crystal fiber (PCF) is designed and proposed for sensing toxic gases with refractive indices ranging from 1.00 to 1.08.

A sustainable and green method for controlling acidic corrosion on mild steel using leaves of Araucaria heterophylla.

There are several studies that announce the inhibitory behavior of this sort of substance to strengthen the shield of metals, which is one of the positive benefits of green inhibitors. In the current investigation, Araucaria heterophylla studied as a green corrosion inhibitor to avert the mild steel during the acidic cleaning. The examination of this plant's ability to control corrosion at different concentrations in the acidic solution used certain expert measures.

Determination of genetic diversity in persimmon accessions using morphological and inter simple sequence repeat markers.

Background: Persimmon (Diospyros kaki L.) belongs to the Ebenaceae family, which includes six genera and about 400 species. This study evaluated the genetic diversity of 100 persimmon accessions from Hatay province, Türkiye using 42 morphological and pomological traits, along with inter simple sequence repeat (ISSR) markers and multivariate analysis.

Comparative analysis of patient demographics and outcomes in teaching and non-teaching hospitals in Iran.

Aims: This study investigates the differences in patient demographics and outcomes between teaching and non-teaching hospitals in Iran. By analyzing these differences, it aims to provide useful information for policymakers to optimize resource allocation, improve patient care, and balance educational and service delivery goals in teaching hospitals.

Materials And Methods: In this cross-sectional investigation, both teaching and non-teaching general hospitals were examined.

High-Efficiency (21.4%) Carbon Perovskite Solar Cells via Cathode Interface Engineering by using CuPc Hole-Transporting Layers.

Carbon perovskite solar cells (C-PSCs) represent a promising photovoltaic technology that addresses the long-term operating stability needed to compete with commercial Si solar cells. However, the poor interface contacts between the carbon electrode and the perovskite result in a gap between C-PSC's performances and state-of-the-art PSCs based on metallic back electrodes. In this work, Cu (II) phthalocyanine (CuPc) was rediscovered as an effective hole-transporting material (HTM) to be coupled with carbon electrodes.

LSD600: the first corpus of biomedical abstracts annotated with lifestyle-disease relations.

Lifestyle factors (LSFs) are increasingly recognized as instrumental in both the development and control of diseases. Despite their importance, there is a lack of methods to extract relations between LSFs and diseases from the literature, a step necessary to consolidate the currently available knowledge into a structured form. As simple co-occurrence-based relation extraction (RE) approaches are unable to distinguish between the different types of LSF-disease relations, context-aware models such as transformers are required to extract and classify these relations into specific relation types.

CRISPR challenges in clinical developments.

CRISPR-Cas (clustered regularly interspaced short palindromic repeats and associated proteins) is a novel genome editing technology with potential applications in treating diseases. Currently, its use in humans is restricted to clinical trials, although its growth rate is significant, and some have received initial FDA approval. It is crucial to examine and address the challenges for this technology to be implemented in clinical settings.

Synergistic topical cancer therapy using dual drug delivery of dexamethasone and 5-fluorouracil via deoxycholic acid micelle-carboxymethyl cellulose hydrogel composites.

Topical formulations containing 5-Fluorouracil (5-FU) have been proven effective in preventing the proliferation of skin cancer cells. However, their use is linked to side effects such as inflammatory and allergic reactions. Dexamethasone (Dexa) is a synthetic glucocorticoid used across allergic reactions which can be useful in preventing the 5-FU side effects.

Characterization and application of polysaccharides produced by Pseudomonas atacamensis M7D1 for chromium (III) removal from tannery effluent.

The wastewater from various industries contaminated with heavy metals poses significant environmental challenges. Biosorption has emerged as a widely used method for removing heavy metals from industrial wastewater. Pseudomonas atacamensis M7D1 is known to produce polysaccharides, but the potential of its polysaccharides as an adsorbent for heavy metal removal still needs to be explored.

Retinal structural alterations in patients with epilepsy taking antiepileptic drugs: A systematic review and meta-analysis of OCT findings.

The impact of various neurodegenerative diseases on the retina has been investigated in recent years using optical coherence tomography (OCT). Epilepsy, classified as a neurodegenerative disorder, has been indicated to affect the structural integrity of the retina. Moreover, there is ongoing debate regarding the relative contribution of disease pathogenesis and the consumption of anti-epileptic drugs (AEDs) to these retinal changes.

Vanillin and IGF1-loaded dual-layer multifunctional wound dressing with micro-nanofibrous structure for full-thickness wound healing acceleration.

Multifunctional dual-layer wound dressings hold significant promise for comprehensive full-thickness wound management by closely mimicking the native skin structure and features. Herein, we employed an innovative approach utilizing electrospinning techniques to develop a dual-layer dressing comprising a microfibrous Ecoflex®-Vanillin (Ex-Vnil) top layer (TL) and a nanofibrous Soluplus®-Insulin-like growth factor-1 (Sol-IGF1) bottom layer (BL). The tensile properties of dual-layer wound dressings were within the standard range for use in skin tissue regeneration.

Marine microbes suppressed Vibrio and enhanced biological performance of euryhaline rotifer, Brachionus plicatilis.

The excessive use of antibiotics in mariculture has surpassed permitted levels, leading to their release into surrounding waters and accumulation in cultured organisms, which poses risks to human health and highlighting the urgent need for alternatives to reduce antibiotic use. Therefore, the present study aimed to test four microbes including Debaryomyces hansenii, Ruegeria mobilis, Lactobacillus plantarum and Bacillus subtilis, on lowering Vibrio, promoting population increase and survival of Brachionus plicatilis. The digestive enzymes activity including α-amylase, lipase and protease, microbial retention and biochemical composition of rotifers were analyzed.

Optimization of environmental and energy performance of egg production using data envelopment analysis (DEA) and life cycle assessment (LCA).

Intensive farming systems can present different environmental concerns. Among the many animal products, eggs are consumed globally as a cheap, valuable source of protein. Iran is among the top 10 egg producing countries in the world.

A mechanistic insight into whey protein isolate (WPI) fibrillation driven by divalent cations.

Protein fibrillation complex mechanisms led to an emerging trend in research for years. The mechanisms behind whey protein isolate (WPI) fibrillation driven by divalent cations remained still a matter of speculation. All cations (Ca, Fe, Mg, and Zn) enhanced the microenvironment polarity through π-π stacking, and the amide I and II shifts confirmed the fibrillation.

Implementing active learning approach to promote motivation, reduce anxiety, and shape positive attitudes: A case study of EFL learners.

Active Learning (AL) represents a transformative instructional approach that departs from traditional methods by immersing students in experiential learning activities such as problem-solving, discussions, role-plays, interactive engagement, and case studies. Despite its widely recognized potential, the effects of AL on psycho-affective constructs in English as a Foreign Language (EFL) contexts remain underexplored. Hence, this study explored the impact of AL on EFL learners' motivation, attitudes, and anxiety in Iran.

The interaction between orexin, sleep deprivation and Alzheimer's disease: Unveiling an Emerging Connection.

Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by progressive cognitive decline and memory loss. Sleep-wake disorders are an extremely predominant and often disabling aspect of AD. Ox is vital in maintaining the sleep-wake cycle and promoting wakefulness.

Evaluation of anti-Pertussis antibody levels in Iranian infants and children: Is it time to include booster acellular Pertussis Vaccines in the immunization schedule?

Introduction: The prevalence of anti-pertussis antibodies among infants and children in Iran has not been thoroughly investigated. Given that recommendations for booster vaccines are based on national disease epidemiology, we aimed to evaluate the seroprevalence of pertussis antibodies among infants and children in an Iranian referral hospital.

Materials And Methods: A total of 1012 infants and children were included in the study.

Using direct method to estimate calcium digestibility of barley and soybean meal in quail chicks.

The availability of calcium (Ca) in poultry diets is influenced by various factors, such as the feed ingredients used. This study assessed the apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of Ca in barley and soybean meal (SBM) in young quail chicks using a direct method. Three diets were formulated, including a Ca-free basal diet to evaluate ileal endogenous calcium losses (IECaL), and two diets with barley or SBM as the sole Ca sources.

Extraction and quantitation of fentanyl in exhaled breath condensate using a magnetic dispersive solid phase based on graphene oxide and covalent organic framework composite and LC-MS/MS analysis.

Free fentanyl is responsible for its pharmacological effects, but its total concentration is typically determined for therapeutic drug monitoring purposes. Determination of fentanyl concentration can help reduce the prescribed doses, leading to fewer side effects and increased effectiveness. Therefore, predicting free drug concentration in pharmaceutical research is crucial.

"Clinical outcomes and healthcare costs in status epilepticus: A multivariable analysis from a tertiary center in a resource-limited setting".

Background: As a debilitating and severe repercussion, the clinical and economic impact of Status epilepticus (SE) has not been thoroughly explored in various regions around the world, especially those with limited resources. Therefore, we aimed to identify the predictors of mortality and healthcare costs associated with SE in one tertiary care center with limited resources.

Methods: This retrospective single-center cohort study, carried out at Namazi Hospital, Shiraz, Iran, included 130 SE cases from March 21, 2021, to March 20, 2022.

TLR/NLRP3 inflammasome signaling pathways as a main target in frailty, cachexia and sarcopenia.

Mobility disability is a common condition affecting older adults, making walking and the performance of activities of daily living difficult. Frailty, cachexia and sarcopenia are related conditions that occur with advancing age and are characterized by a decline in muscle mass, strength, and functionality that negatively impacts health. Chronic low-grade inflammation is a significant factor in the onset and progression of these conditions.