Efficacy of hyperimmunized egg yolk antibodies (IgY) against Campylobacter jejuni: In Vitro and In Vivo evaluations.

Campylobacter infections are a prevalent cause of diarrheal disease in humans and are the most significant zoonotic pathogens worldwide. Human campylobacteriosis is generally via ingestion of contaminated poultry products. However, based on recent studies chicken egg yolk antibody (IgY) powder has great potential to reduce the cecum load of Campylobacter jejuni (C.

Successful management of large conjunctival squamous cell carcinoma with excisional biopsy, topical interferon, and amniotic membrane grafting: A case report.

Introduction And Importance: Conjunctival squamous cell carcinoma (SCC) is the most advanced form of ocular surface squamous neoplasia (OSSN), with varying incidence rates influenced by factors such as age, UV exposure, and occupation. Early detection is crucial, but misdiagnosis is common, especially when SCC mimics benign conditions like pterygium.

Case Presentation: An 83-year-old Caucasian male farmer presented with a rapidly enlarging nasal limbal lesion, initially misdiagnosed as pterygium.

Examining the determinants of resilience and mental stress in emergency department nurses.

Background: Emergency departments (ED) are characterized by highly dynamic environments. This study aimed to identify determinants of resilience and mental stress among ED nurses.

Methods: A cross-sectional, analytical design was employed to assess 316 emergency nurses in Kermanshah hospitals using a convenience sampling method.

The relationship between health-related quality of life and academic success in nursing students: the mediating role of academic burnout and academic motivation.

Background: The identification of the key factors that affect academic success in nursing students, including health-related quality of life, academic burnout, and academic motivation, has been of the utmost importance to date. In this context, the present study sought to examine the relationship between health-related quality of life and academic success, with academic burnout and academic motivation mediating that relationship.

Methods: This analytical cross-sectional study included 262 eligible nursing students selected through convenience sampling from the School of Nursing and Midwifery at Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Health literacy and its relationship with mental health and quality of life in freshmen students.

Introduction: Health literacy is an effective indicator of people's health level. Therefore, this study aimed to investigate health literacy and its relationship with mental health and quality of life in first-year medical sciences students.

Methods And Materials: The cross-sectional study was conducted on freshmen- students of Babol University of Medical Sciences, Iran.

Intra-Arterial Stem Cell Injection for Treating Various Diseases: A New Frontier in Interventional Radiology.

This article provides radiologists with insights into stem cells' functions, sources, and potentially successful clinical treatments via intravascular injection in organs such as the liver, kidney, pancreas, musculoskeletal system, and for ischemic conditions affecting the brain, heart and limbs. Understanding stem cells' significance in interventional radiology and its limitations enables tailored interventions for diverse conditions, ensuring efficient medical care and optimal treatment selection.

Heterogeneity in category recognition across the visual field.

Visual information emerging from the extrafoveal locations is important for visual search, saccadic eye movement control, and spatial attention allocation. Our everyday sensory experience with visual object categories varies across different parts of the visual field which may result in location-contingent variations in visual object recognition. We used a body, animal body, and chair two-forced choice object category recognition task to investigate this possibility.

Manganese recovery from electric arc furnace dust bioleachate: Evaluation of different precipitation agents.

This study optimized a one-step precipitation process for manganese recovery from a complex medium-bioleachate obtained from electric arc furnace dust (EAFD). The effects of pH variations and different precipitation agents, including acetone, ethanol, oxalic acid, and ammonium hydroxide, were investigated for manganese recovery. While acetone and ethanol facilitated precipitation, they did not lead to the formation of a specific manganese precipitate.

Evaluating the anticancer effects of carnosic acid against breast cancer: An In Vitro investigation.

Background: Carnosic acid (CA) has potential anti-cancer properties, but its effectiveness can be improved by combining it with Folic acid (FA). This research aimed to evaluate the impact of CA and CA-FA conjugate on breast cancer cell lines (MCF-7, MDA-MB-231, and MCA10).

Materials And Methods: The viability of the cell lines was measured using the MTT assay, and the IC₅₀ was determined to compare the cytotoxicity of CA and CA-FA.

Osteogenic differentiation of mesenchymal stem cell on poly sorbitol sebacate scaffold under shear stress in a bioreactor.

Mechanical loading plays a pivotal role in regulating bone anabolic processes. Understanding the optimal mechanical loading parameters for cellular responses is critical for advancing strategies in orthopedic bioreactor-based bone tissue engineering. This study developed a poly (sorbitol sebacate) (PSS) filmscaffold with a sorbitol-to-sebacic acid molar ratio of 1:4.

PFAS contamination in tap water: Target and suspect screening of zwitterionic, cationic, and anionic species across Canada and beyond.

This study investigated the occurrence of perfluoroalkyl and polyfluoroalkyl substances (PFAS), including anionic, cationic, and zwitterionic compounds, in drinking water. Between 2021-2023, an expanded list of 76 target PFAS was screened in tap water samples mainly from Canada, but also including tap water samples from the Eastern United States, Mexico, South America (Argentina), the Caribbean (Dominican Republic, Cuba), Africa (Algeria, Cameroon, Central African Republic, Morocco, Rwanda, Tunisia), Europe (France, Greece, Italy, Spain, and the United Kingdom) and Asia (Japan, Vietnam, Iran, and Türkiye). An additional ∼ 200 suspect-target PFAS were screened using high-resolution Orbitrap mass spectrometry.

Facile Aqueous Route to Large-Scale Superhydrophilic TiO-Incorporated Graphitic Carbon Nitride-Coated Ni(OH) and NiP Nano-Architecture Arrays as Efficient Electrocatalysts for Enhanced Hydrogen Production.

Water splitting by an electrochemical method to generate hydrogen gas is an economic and green approach to resolve the looming energy and environmental crisis. Designing a composite electrocatalyst having integrated multichannel charge separation, robust stability, and low-cost facile scalability could be considered to address the issue of electrochemical hydrogen evolution. Herein, we report a superhydrophilic, noble-metal-free bimetallic nanostructure TiO/NiP coated on graphitic polyacrylonitrile carbon fibers (g-C/TiO/NiP) using a facile hydrothermal method followed by phosphorylation.

Application of 99mTc-FAPI-46 Imaging in a Patient With Medullary Thyroid Carcinoma: Navigating the Landscape of Novel Radiotracers.

We present the case of a 58-year-old man with metastatic medullary thyroid carcinoma refractory to conventional therapies, including peptide receptor radionuclide therapy. Despite multiple interventions, serum calcitonin and carcinoembryonic antigen levels continued to rise. Subsequent evaluation with 99mTc-FAPI-46 revealed remarkable uptake in metastatic lesions, suggesting a potential role for FAPI-labeled radioisotopes in the management of medullary thyroid carcinoma.

The potential role of machine learning and deep learning in differential diagnosis of Alzheimer's disease and FTD using imaging biomarkers: A review.

Introduction: The prevalence of neurodegenerative diseases has significantly increased, necessitating a deeper understanding of their symptoms, diagnostic processes, and prevention strategies. Frontotemporal dementia (FTD) and Alzheimer's disease (AD) are two prominent neurodegenerative conditions that present diagnostic challenges due to overlapping symptoms. To address these challenges, experts utilize a range of imaging techniques, including magnetic resonance imaging (MRI), diffusion tensor imaging (DTI), functional MRI (fMRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT).

Synchronization of two coupled massive oscillators in the time-delayed Kuramoto model.

We examine the impact of the time delay on two coupled massive oscillators within the second-order Kuramoto model, which is relevant to the operations of real-world networks that rely on signal transmission speed constraints. Our analytical and numerical exploration shows that time delay can cause multi-stability within phase-locked solutions, and the stability of these solutions decreases as the inertia increases. In addition to phase-locked solutions, we discovered non-phase-locked solutions that exhibit periodic and chaotic behaviors, depending on the amount of inertia and time delay.

Ultra-compact quintuple-band terahertz metamaterial biosensor for enhanced blood cancer diagnostics.

Cancer and its diverse variations pose one of the most significant threats to human health and well-being. One of the most aggressive forms is blood cancer, originating from bone marrow cells and disrupting the production of normal blood cells. The incidence of blood cancer is steadily increasing, driven by both genetic and environmental factors.

Tomato fruit quality and nutrient dynamics under water deficit conditions: The influence of an organic fertilizer.

Drought adversely affects the growth and performance of plants. By contrast, the application of organic modifiers can improve plant growth by supplying nutrients and water. The influence of foliar application of organic fertilizer under water deficit conditions on growth traits, chemical composition, and fruit quality of tomato (Lycopersicon esculentum Mill.

Effect of fatigue on neuromuscular and biomechanical variables after anterior cruciate ligament reconstruction: a systematic review.

Introduction: This systematic review is aimed to evaluate the outcomes of published studies on the topic of fatigue-induced neuromuscular and biomechanical changes after anterior cruciate ligament (ACL) reconstruction.

Evidence Acquisition: The identification of studies involved a search across three databases - PubMed, Scopus, and Sportdiscus - until July 2023. The key terms utilized were fatigue, anterior cruciate ligament, biomechanics, electromyography, and landing.

Human TRMT1 and TRMT1L paralogs ensure the proper modification state, stability, and function of tRNAs.

The tRNA methyltransferase 1 (TRMT1) enzyme catalyzes the N2,N2-dimethylguanosine (m2,2G) modification in tRNAs. Intriguingly, vertebrates encode an additional tRNA methyltransferase 1-like (TRMT1L) paralog. Here, we use a comprehensive tRNA sequencing approach to decipher targets of human TRMT1 and TRMT1L.

Decreased expression of hsa-miR-142-3p and hsa-miR-155-5p in common variable immunodeficiency and involvement of their target genes and biological pathways.

Common variable immunodeficiency (CVID) is the most common symptomatic and heterogeneous type of inborn errors of immunity (IEI). However, the pathogenesis process of this disease is often unknown. Epigenetic modifications may be involved in unresolved patients.

Safety of 1 mcg/mL as the starting dose in cluster protocol for hymenoptera immunotherapy.

Background: Hymenoptera venom allergy is a potentially severe allergic reaction in the general population. The only preventative approach in these cases is venom immunotherapy (VIT), which follows different protocols. The recommended initial dose is 0.

Efficacy of melatonin on drug- or contrast-induced acute kidney injury: a systematic review and GRADE-assessed meta-analysis of experimental and clinical studies.

Objective: The objective of this systematic review and meta-analysis was to assess the efficacy of melatonin in drug- or contrast-induced AKI in preclinical and clinical studies.

Methods: PubMed, Embase, Scopus, Web of Science (WOS), the Cochrane Database of Systematic Reviews (CDSR), and clinical trials.GOV from the beginning until August 1, 2024.

Revitalizing Vision: Eye Drops and Corneal Limbal Stem Cells Survival.

In the quest to transform vision care, researchers have been investigating novel methods to boost the efficacy of eye drops and enhance the survival of corneal limbal stem cells. Aimed at rejuvenating vision, these innovations seek to tackle a range of ocular conditions and restore sight to those in need. This article examines the most recent advancements in eye drops and corneal limbal stem cells, highlighting their potential to revolutionize ophthalmology.

Protective effects of polydatin amphiphilic chitosan nanocarriers against an aluminum chloride-induced model of Alzheimer's disease in rats: relevance to its anti-inflammatory and antioxidant effects.

Alzheimer's disease (AD) is the most frequent cause of dementia. Since there are complex pathophysiological mechanisms behind AD, and there is no effective treatment strategy, it is necessary to introduce novel multi-targeting agents with fewer side effects and higher efficacy. Polydatin (PD) is a naturally occurring resveratrol glucoside employing multiple mechanisms toward neuroprotection.