299,446 results match your criteria: "Iran; Food and Drug Control Laboratories References Center FDLCRC[Affiliation]"

Percutaneous valve implantation or surgical replacement with mechanical or biological valves are standard therapies for severe valvular heart diseases. Prosthetic valve thrombosis, though rare, is a serious complication, particularly with mechanical prostheses. This study aimed to investigate the predictive value of platelet volume parameters, including mean platelet volume (MPV), platelet distribution width (PDW), and platelet-large cell ratio (P-LCR), for valvular thrombosis risk in patients undergoing valve replacement therapy.

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This study investigates the gross morphological and morphometric characteristics of thoracic and lumbar intervertebral discs (IVDs) in guinea pigs, utilising micro-CT imaging and anatomical dissection. The findings reveal 13 thoracic and six lumbar IVDs were identified, with thoracic discs transitioning from rounded forms at T1-T3 to triangular and heart-shaped structures at T4-T13, while lumbar IVDs exhibited a consistently flattened heart shape. Morphometric analysis revealed statistically significant differences, with lumbar IVDs being larger in lateral and dorsoventral width, disc area, annulus fibrosus (AF) area and nucleus pulposus (NP) area, and ventral height compared to thoracic discs.

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The origin of domestic sheep (Ovis aries) can be traced back to the Asian mouflon (Ovis gmelini), in the Near East around 10 000 years ago. Genetic divergence within mouflon populations can occur due to factors such as geographical isolation, social structures, and environmental pressures, leading to different affinities with domestic sheep. However, few studies have reported the extent to which mouflon sheep contribute to domestic sheep in different regions.

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The status of sodium intake and excretion and the primary dietary sources of sodium in Iranian adults, a comprehensive pilot study.

Cardiovasc Endocrinol Metab

March 2025

Department of Food and Nutrition Policy and Planning Research, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Coronary artery disease and hypertension are the leading causes of death and disability worldwide, primarily due to high sodium intake. Therefore, accurate assessment of the status of sodium intake and excretion is crucial. The present study aimed to assess the dietary sodium intake and excretion in Iranian population.

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Objective: The purpose of this study was to evaluate the association of pain-related anxiety on abdominal muscles thickness during standing postural tasks among individuals with chronic low back pain (CLBP).

Methods: We obtained responses to a pain-related anxiety symptoms questionnaire from 50 participants with CLBP. We then separated participants into high (11 men, 14 women) and low pain-related anxiety (13 men, 12 women) groups and compared assessments of their lateral abdominal muscles thickness during standing tasks on a computerized balance assessment device, using one static level and 2 movable levels (levels 6 and 3 are represented easy and difficult tasks respectively).

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Objective: The purpose of this review was to evaluate the effectiveness of dry needling (DN) to improve function, proprioception, and balance and to reduce pain in individuals with chronic ankle instability (CAI).

Methods: We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for this review. We searched PubMed, ISI Web of Knowledge, Scopus, Science Direct, Google Scholar, and ProQuest databases from inception until July 2022 using the PICO (population, intervention, comparison, outcome) method.

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High-performance modified LDH for green one-pot synthesis of pyrido[2,3-]pyrimidines.

Heliyon

January 2025

Department of Organic Chemistry, Faculty of Chemistry and Petroleum Sciences, Bu-Ali Sina University, Hamedan, Iran.

This study introduces a new nano catalyst tailored for the eco-friendly synthesis of pyrido[2,3-]pyrimidine via a three-component one-pot reaction involving benzaldehydes, malononitrile, and uracil. To achieve this objective, we anchored copper acetate onto the surface of layered double hydroxides modified with 1,3‑benzenedisulfonyl amide (BDSA) (LDH@PTRMS@BDSA@Cu(NO)), which exhibited remarkable activity and selectivity. The main benefits of this method include high product yield, swift reaction times, straightforward purification, catalyst reusability, and the employment of a mild reaction process.

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In this study, a Cu@Ag core-shell was synthesized using a co-precipitation method. To create a new electrochemical sensor, a Cu@Ag core-shell with conductive polymers such as polyalizarin yellow R (PA) and Nafion (Nf) was immobilized on the surface of a glassy carbon electrode (Cu@Ag-Nf/PA/GCE). X-ray diffraction analysis (XRD), energy dispersive X-ray analysis (EDX), transmission electron microscopy (TEM), and Fourier Transform Infrared Spectroscopy (FTIR) techniques were employed to characterize the Cu@Ag-Nf/PA/GCE.

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Background: Being overweight/having obesity is a prevalent condition not only among the general population but also among individuals with special occupations such as police officers, where fitness is often a necessity. The present study's aim was to assess how much a psychoeducational intervention based on social cognitive theory (SCT) would be helpful for encouraging weight loss behaviors among police officers.

Methods: In a randomized control trial, 102 police officers who were overweight or had obesity voluntarily registered for a weight loss program and were assigned to either an intervention or control group.

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Shiga Toxin: Emerging Producer Strains, Prophylactic Approaches, and Application in Cancer Therapy.

J Cancer Prev

December 2024

Infectious Disease Research Center, Avicenna Institute of Clinical Sciences, Hamadan, IranAvicenna Health Research Institute, Hamadan University of Medical Sciences, Hamadan, Iran.

Shiga toxin-producing is the most prevalent bacterial strain responsible for Shiga toxin-related infections. While Shiga toxin is inherently toxic, it has potential therapeutic applications as a component of anticancer drugs. Despite its association with infections and harmful effects on human health, Shiga toxin is being explored as a viable element in drug delivery systems targeting cancer cells.

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Background And Aims: This study aimed to evaluate the effectiveness, safety, and satisfaction rates of three different lateral matricectomy methods for treating ingrown toenails: 90% phenol, 100% trichloroacetic acid (TCA), and radiofrequency (RF) ablation. Our objective was to identify which method offers superior outcomes regarding postoperative pain, healing time, aesthetic results, and complication rates.

Methods: Conducted between August 2022 and June 2023, the study included 12 eligible patients divided into three groups: Group 1 underwent lateral matricectomy with 90% phenol, Group 2 with 100% TCA, and Group 3 with RF treatment.

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Background: This systematic review and meta-analysis evaluates peripheral and CNS BDNF levels in glioma patients.

Methods: Following PRISMA guidelines, we systematically searched databases for studies measuring BDNF in glioma patients and controls. After screening and data extraction, we conducted quality assessment, meta-analysis, and meta-regression.

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Pollen Diversity in the Tribe Cardueae (Asteraceae) and Its Taxonomic Significance.

Microsc Res Tech

January 2025

Department of Plant Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran.

The Cardueae with about 74 genera and 2500 species is one of the largest tribes of the family Asteraceae. The taxonomy of the Cardueae is complicated and unresolved, as it contains the largest and most diverse genera. The main distribution centers of the Cardueae are in the eastern and western Mediterranean, the western Irano-Turanian region, central Asia, and North Africa.

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Western flower thrips, Frankliniella occidentalis (Thysanoptera: Thripidae) is an invasive agricultural pest with developed resistance to abamectin in some strains due to frequent treatment with the pesticide. In this study, we examined differentially expressed proteins (DEPs) between abamectin-resistant (Aba; under abamectin selective pressure) and susceptible strains (Aba; without abamectin selective pressure) of F. occidentalis.

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Background: Increased levels of inflammation in cancer patients and survivors can make them more prone to muscle wasting and sarcopenia. Diet can be an appropriate treatment for alleviating patient complications. Therefore, this study was performed to determine the association between sarcopenia and its components with the dietary inflammatory index (DII) among breast cancer survivors.

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Background: Urinary tract infection (UTI) is a frequent health-threatening condition. Early reliable diagnosis of UTI helps to prevent misuse or overuse of antibiotics and hence prevent antibiotic resistance. The gold standard for UTI diagnosis is urine culture which is a time-consuming and also an error prone method.

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Background: Intensive care unit (ICU) nurses work under heavy workloads, which can lead to serious consequences for nurses' outcomes and patient safety. This study aimed to examine the relationship between professional quality of life (Pro QOL), and sleep quality among ICU nurses during the COVID-19 outbreak.

Methods: A cross-sectional and multicentre study was conducted on 253 nurses in 20 COVID-19 ICUs in four major teaching hospitals from July 2021 to June 2022.

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Background: Emergency departments (ED) are characterized by highly dynamic environments. This study aimed to identify determinants of resilience and mental stress among ED nurses.

Methods: A cross-sectional, analytical design was employed to assess 316 emergency nurses in Kermanshah hospitals using a convenience sampling method.

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Background: This study aims to compare Lung Ultrasound (LUS) findings with High-Resolution Computerized Tomography (HRCT) and Pulmonary Function Tests (PFTs) to detect the severity of lung involvement in patients with Usual Interstitial Pneumonia (UIP) and Non-Specific Interstitial Pneumonia (NSIP).

Methods: A cross-sectional study was conducted on 35 UIP and 30 NSIP patients at a referral hospital. All patients underwent LUS, HRCT, and PFT.

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Background: The identification of the key factors that affect academic success in nursing students, including health-related quality of life, academic burnout, and academic motivation, has been of the utmost importance to date. In this context, the present study sought to examine the relationship between health-related quality of life and academic success, with academic burnout and academic motivation mediating that relationship.

Methods: This analytical cross-sectional study included 262 eligible nursing students selected through convenience sampling from the School of Nursing and Midwifery at Shahid Beheshti University of Medical Sciences, Tehran, Iran.

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Introduction: Health literacy is an effective indicator of people's health level. Therefore, this study aimed to investigate health literacy and its relationship with mental health and quality of life in first-year medical sciences students.

Methods And Materials: The cross-sectional study was conducted on freshmen- students of Babol University of Medical Sciences, Iran.

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Background: Cytokeratins are intracellular proteins known as diagnostic biomarkers or prognostic factors for certain cancers. Cytokeratin 19 (CK-19) expression has been proven to have prognostic value for some cancers, but its relationship with others, such as prostate cancer (PCa), remains unclear. This systematic review article aimed to examine the relationship between CK-19 expression and prostate adenocarcinoma (PAC).

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Background: Inadequate treatment responses, chemotherapy resistance, significant heterogeneity, and lengthy treatment durations create an urgent need for new pancreatic cancer therapies. This study aims to investigate the effectiveness of gemcitabine-loaded nanoparticles enclosed in an organo-metallic framework under ketogenic conditions in inhibiting the growth of MIA-PaCa-2 cells.

Methods: Gemcitabine was encapsulated in Metal-organic frameworks (MOFs) and its morphology and size distribution were examined using transmission electron microscopy (TEM) and Dynamic light scattering (DLS) with further characterization including FTIR analysis.

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Background: Colorectal cancer (CRC) is a common gastrointestinal cancer, and even though oxaliplatin chemotherapy is effective, there is a high likelihood of relapse, indicating the presence of oxaliplatin-resistant CRC. Therefore, it is crucial to comprehend the molecular mechanisms of oxaliplatin resistance and develop effective strategies to counter drug resistance. Numerous studies have demonstrated the close association between microRNAs (miRNAs) and drug resistance in CRC.

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Background: Each of the Coronavirus disease 2019 (COVID-19) vaccines has its characteristics that can affect their effectiveness in preventing hospitalization and patient mortality. The present study aimed to determine the effectiveness of COVID-19 vaccines, including whole-virus, protein-based, and vector-based on COVID-19 infection, hospitalization, and mortality.

Methods: The current cohort study was conducted using the data of all people who received at least two doses of each type of COVID-19 vaccine from March 2020 to August 2022 in Khorasan Rzavi province.

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