Developing a Structurally Modified Mechanical Lumped Model of the Human Tibia and Shin Guard Using Modal Analysis.

Shins are one of the most vulnerable bones in human body. Shin guards are evaluated by their effectiveness in reducing the force applied to the bone. In this study, a structural modified mechanical lumped model of the shin guard was developed to provide maximum force distribution using physical parameter change modification technique and genetic algorithm.

Effects of Enriched Environment on Barrel Cortex and Hippocampus Function following Somatosensory Damage in Rat.

Objectives: This study investigated the effects of environmental enrichment (EE) on the behavior and histological alterations of rats with barrel cortex damage.

Methods: Forty-eight adult male rats were divided into Control (Ctrl), Lesion, Lesion+EE.S (Lesion+Standard Enriched Environment, and Lesion+EE.

Improve the behavioral auditory attention training effects on the Speech-In-Noise perception with simultaneous electrical stimulation in children with hearing loss: A randomized clinical trial.

Background: Auditory attention is an important cognitive factor that significantly affects speech perception in noisy environments. Hearing loss can impact attention, and it can impair speech perception in noise. Auditory attention training improves speech perception in noise in children with hearing loss.

Quantification of ochratoxin A in a coffee sample utilizing an electrochemical aptasensor fabricated through encapsulation of toluidine blue within a Zn-based metal-organic framework.

An electrochemical aptasensor has been developed specifically for the sensitive and selective determination of ochratoxin A (OTA), one of the most important mycotoxins. The aptasensor utilizes a glassy carbon electrode that has been modified with toluidine blue (TB) encapsulated in a Zn-based metal-organic framework (TB@Zn-MOF). The results demonstrate that in the presence of OTA, the peak current of the differential pulse voltammogram (DPV) related to TB oxidation is notably decreased.

One direction? Cultural aspects of the mental number line beyond reading direction.

Spatial-Numerical Associations (SNAs) refer to the demonstrations of spatial processing of numbers. The Mental Number Line (MNL) is a representation model describing numbers as aligning left-to-right (LR) and was suggested to account for directional biases in participants' responses during numerical tasks. One common behavioral demonstration of this is the Spatial-Numerical Associations of Response Codes (SNARC) effect, which describes faster left-/right-hand responses to smaller/larger numbers, respectively.

Designing and implementation of a mobile application for teaching population oral health needs assessment for dental students; a non-randomized trial.

Objective: This study investigates the effectiveness of a newly developed smartphone-based application for teaching population oral health needs assessment to undergraduate dental students.

Methods: Target population in this study consisted of all students of Shahid Beheshti School of dentistry in the 7 and 8 semesters in the year 2023. The intervention group (7 semester) received teaching about population oral health needs assessment based on the book "Oral health surveys; basic methods", by means of an application, while the control group (8 semester) received the same content through self-learning activity.

Understanding the complex function of gut microbiota: its impact on the pathogenesis of obesity and beyond: a comprehensive review.

Obesity is a multifactorial condition influenced by genetic, environmental, and microbiome-related factors. The gut microbiome plays a vital role in maintaining intestinal health, increasing mucus creation, helping the intestinal epithelium mend, and regulating short-chain fatty acid (SCFA) production. These tasks are vital for managing metabolism and maintaining energy balance.

Using right colon interposition in patients with caustic ingestion, an introduction of a new surgical technique for post-gastrectomy reconstruction: a case series.

Background: Corrosive substance ingestion is rare but can cause severe injury, especially to the upper gastrointestinal tract, and can be a potentially fatal event. Various surgical procedures have been advocated for gastroesophageal reconstruction, but especially those using the right colon, when the ileocecal valve is preserved for gastric reconstruction, are briefly exposed in literature and have not been studied in humans by controlled studies. Using the right colon is believed to be beneficial because of the anti-reflux mechanism of the ileocecal valve.

Global prevalence of Helicobacter pylori antibiotic resistance among children in the world health organization regions between 2000 and 2023: a systematic review and meta-analysis.

Background: Helicobacter pylori infection causes gastritis, peptic ulcers, and gastric cancer. The infection is typically acquired in childhood and persists throughout life. The major impediment to successful therapy is antibiotic resistance.

Plasma exchange as a rescue therapy for treatment-resistant thyroid storm with concurrent heart failure: a literature review based on a case report.

Introduction: Thyroid storm or severe hyperthyroidism can present with various signs and symptoms. They are mostly controlled by general treatment, such as anti-thyroid drugs and other medications to control clinical features. However, in rare cases, they are more severe, and they only respond to more aggressive treatments, such as plasmapheresis and total thyroidectomy.

Effect of intracanal cryotherapy on post-operative pain in single-visit endodontic retreatment: a randomized clinical trial.

Background: This randomized clinical trial aimed to evaluate the effect of intracanal cryotherapy with 2-4 °C normal saline irrigation on post-operative pain after single-visit non-surgical root canal retreatment.

Methods: Forty-six single-rooted, single-canal teeth requiring non-surgical root canal retreatment were randomly assigned to two groups (n = 23): a cryotherapy group and a control group. All the treatments were completed during a single visit.

Healthcare utilization among people with disabilities in Iran: what predictors are associated with medical visits?

Background: Ensuring equitable access to healthcare services for individuals with disabilities poses a significant challenge for healthcare systems. This research aimed to explore the factors affecting medical visits among this population.

Method: This cross-sectional study in Iran involved data from 766 adults with disabilities aged 18 and older.

High-performance breast cancer diagnosis method using hybrid feature selection method.

Objectives: One of the primary causes of the women death is breast cancer. Accurate and early breast cancer diagnosis plays an essential role in its treatment. Computer Aided Diagnosis (CAD) system can be used to help doctors in the diagnosis process.

A systematic review and meta-analysis: rising prevalence of colistin resistance in ICU-acquired Gram-negative bacteria.

Colistin is a last-resort treatment for multidrug-resistant Gram-negative bacterial infections, particularly in critically ill patients. Nevertheless, it remains a major threat to public health. We assessed the proportion of colistin-resistant Gram-negative isolates from intensive care unit (ICU) infections in different years, areas, pathogens, and antimicrobial susceptibility tests (AST).

Examining Mental Health Changes Before and After Rhinoplasty: An Analytical Study.

This study aimed to explore the mental health status of individuals seeking rhinoplasty before and 3 months after surgery. This study was conducted in 2022 at Velayat Hospital, involving patients aged 18-60 who were seeking rhinoplasty, selected using convenience sampling method. Exclusion criteria included prior nasal surgery and severe psychiatric disorders without clearance from a psychiatrist.

Evaluation of the Effects of Amitraz on the Enzyme Activity and Stability of Lysozyme: Spectroscopic and MD Simulation Approach.

The binding interaction of food preservatives and pesticides has emerged as a matter of paramount importance as it not only presents potential health hazards but also carries substantial consequences for food processing and preservation. Herein, the mechanism of interaction between lysozyme and Amitraz was explored through spectroscopic and computational techniques. Spectral investigations indicated the spontaneous nature and stability of the lysozyme-Amitraz complex.

Recent advances in groundwater pollution research using machine learning from 2000 to 2023: a bibliometric analysis.

Groundwater pollution has become a global challenge, posing significant threats to human health and ecological environments. Machine learning, with its superior ability to capture non-linear relationships in data, has shown significant potential in addressing the groundwater pollution issues. This review presents a comprehensive bibliometric analysis of 1,462 articles published between 2000 and 2023, offering an overview of the current state of research, analyzing development trends, and suggesting future directions.

High-titer rheumatologic markers in serum of veterans with severe pulmonary complications 25-30 years after sulfur mustard exposure.

Sulfur mustard (SM), known as the "king of toxic agents," continues to pose a potential danger due to its ability to cause widespread damage, including ongoing corrosive effects. We aimed to determine the rheumatologic markers in SM veterans suffering from severe pulmonary manifestations. The serologic markers, including ANA, anti-DNA, rheumatoid factor (RF), and CRP, between SM-exposed veterans (n = 229) with severe problems and not-SM-exposed residents with no pulmonary disease history (n = 63), 25-30 years after SM exposure were compared.

Magnetic polyoxometalate composite stabilized on the woven cotton yarn as a sorbent for thin film microextraction of some selected nonsteroidal anti-inflammatory drugs followed by high-performance liquid chromatography-ultraviolet detection.

A new thin film was fabricated using FeO@SiO-polyoxometalate (POM) as the coating and it was coupled with a HPLC-UV to develop a method for the selective determination of ibuprofen, paracetamol and diclofenac (as the model analytes) from human plasma and urine samples. The prepared magnetic POM was coated on the pores and surface of cotton yarn to prepare the extracting device. The prepared sorbent was characterized by several techniques including: FT-IR, XRD, BET, SEM, and VSM analysis.

Tele-exercise in multiple sclerosis: Systematic review and meta-analysis of effects on fatigue, depression, and overall health.

Background: Multiple sclerosis (MS) profoundly influences fatigue, depression, various physical and mental symptoms, and quality of life (QoL). Rehabilitation, including exercise training, has improved outcomes of MS, yet is often undertaken in facilities with direct supervision which present substantial barriers for accessibility and scalability. The delivery of exercise remotely via technology (tele-exercise) might overcome those barriers and improve outcomes in MS.

Gingival crevicular fluid level of tumor necrosis factor-alpha as a valuable biomarker for estimation of the efficacy of adjunctive antimicrobial photodynamic therapy in stage II-IV periodontitis: a systematic review and meta-analysis.

Purpose: This systematic review and meta-analysis aimed to assess the gingival crevicular fluid (GCF) level of tumor necrosis factor-alpha (TNF-alpha) as a valuable inflammatory cytokine for estimation of the efficacy of adjunctive antimicrobial photodynamic therapy (aPDT) in stage II-IV periodontitis patients.

Methods: This review was conducted in accordance with the PRISMA statements, and registered in PROSPERO (CRD42022321211). An electronic search was conducted for articles comparing the efficacy of aPDT versus scaling and root planing (SRP) published up until June 2023.

Giant prolactinoma with progressive cranial settling and central herniation: a case report.

Background: Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical intervention. The present case is the largest reported giant prolactinoma (99 × 72 × 57 mm).

Development of a hydrogel-based three-dimensional (3D) glioblastoma cell lines culture as a model system for CD73 inhibitor response study.

Background: Despite the development of various therapeutic approaches over the past decades, the treatment of glioblastoma multiforme (GBM) remains a major challenge. The extracellular adenosine-generating enzyme, CD73, is involved in the pathogenesis and progression of GBM, and targeting CD73 may represent a novel approach to treat this cancer. In this study, three-dimensional culture systems based on three hydrogel compositions were characterized and an optimal type was selected to simulate the GBM microenvironment.

A study on the workplace cultural violence against nurses: a systematic review and meta-analysis.

Introduction: Cultural violence includes any offensive behavior regarding ethnicity, race, language, religion, and place of birth devaluing human dignity. The purpose of this study was to investigate workplace cultural violence against nurses by systematic review and meta-analysis.

Materials And Methods: The guideline of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was followed.