8,316 results match your criteria: "Iodine Deficiency"

Research on food security issues considering changes in rainfall.

Sci Rep

August 2024

School of Economics, Fujian Normal University, Fuzhou, Fujian, 350007, People's Republic of China.

Ensuring food security is not only vital to the adequate supply of food in the world, but also the key to the economic development and social stability of various countries. Based on the panel data of 29 provinces in China from 2016 to 2020, this paper selects the number of foodborne diseases patients and iodine deficiency disease patients as reference objects, uses stunting rate of children under 5 years old, malnutrition rate of children under 5 years old, obesity rate of children under 5 years old, and newborn visit rate to measure improving nutrition, proposes Meta Entropy Two-Stage Dynamic Direction Distance Function (DDF) Under an exogenous Data Envelopment Analysis (DEA) model to measure the efficiency of hunger eradication, food security, and improving nutrition under the influence of exogenous variable rainfall. The research results indicate that the sustainability of China's agricultural economy is insufficient, and the focus of attention should be different in different stages.

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Iodine is a trace element with an important role in human health. Iodine deficiency is a global health problem that can provoke iodine-deficiency-related thyroid disorders, such as endemic goitre, hypothyroidism, thyroid cancer, etc. Study of iodine in the soils and vegetation was conducted from 2008 to 2022 in the Bryansk and Oryol regions of Russia.

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Neutrophils (polymorphonuclear leukocytes, PMNs) comprise a major component of the immune cell infiltrate during acute mucosal inflammation and have an important role in molding the inflammatory tissue environment. While PMNs are essential to clearance of invading microbes, the major PMN antimicrobial enzyme myeloperoxidase (MPO) can also promote bystander tissue damage. We hypothesized that blocking MPO would attenuate acute colitis and prevent the development of chronic colitis by limiting bystander tissue damage.

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Salt Reduction and Iodine Fortification Policies Are Compatible: Perspectives for Public Health Advocacy.

Nutrients

August 2024

Human Nutrition Laboratory, Institute of Food, Nutrition and Health, ETH Zürich, 8092 Zürich, Switzerland.

Cardiovascular diseases account for almost 18 million deaths annually, the most of all non-communicable diseases. The reduction of dietary salt consumption is a modifiable risk factor. The WHO recommends a daily sodium intake of <2000 mg but average consumption exceeds this in many countries globally.

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Thyroid function is closely linked to nutrition through the diet-gut-thyroid axis. This narrative review highlights the influence of nutritional components and micronutrients on thyroid development and function, as well as on the gut microbiota. Micronutrients such as iodine, selenium, iron, zinc, copper, magnesium, vitamin A, and vitamin B12 influence thyroid hormone synthesis and regulation throughout life.

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Incomplete ablation of thyroid cancer: Achilles' Heel?

BMC Endocr Disord

August 2024

The Seventh Department of General Sur gery, The First Hospital of Lanzhou University, Lanzhou, Gansu Province, 730000, China.

Article Synopsis
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Article Synopsis
  • This study examines the prevalence trends of Vitamin A, iodine, and protein-energy malnutrition from 1990 to 2019, focusing on how these deficiencies affect children and adolescents in low-income countries.
  • It uses data from the Global Burden of Disease Study to analyze variations by gender, region, and age group, highlighting the need for targeted health interventions.
  • Key findings show Central Sub-Saharan Africa has the highest rates of Vitamin A and iodine deficiencies, while South Asia leads in protein-energy malnutrition, indicating significant regional health disparities.
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Balancing the benefits and risks of China's national salt iodization policy over 30 years using disability-adjusted life years (DALYs): a systematic review and meta-analysis.

Crit Rev Food Sci Nutr

August 2024

National Engineering Research Center of Industrial Wastewater Detoxication and Resource Recovery, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, China.

Both insufficient and excessive iodine intake can lead to thyroid-related disorders. Although China has made progress in eliminating iodine deficiency over the past few decades, the incidence of thyroid cancer is increasing. Currently, there is a lack of relevant research on the tradeoff between the benefits and risks of salt iodization in China.

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Hypothyroidism due to biallelic variants in IYD: description of 4 families and a novel variant.

Eur J Endocrinol

August 2024

Paediatric Endocrinology Unit, Université Libre de Bruxelles (ULB), Hôpital Universitaire de Bruxelles (H.U.B.), Hôpital Universitaire des Enfants Reine Fabiola (HUDERF), 1020 Bruxelles, Belgium.

Biallelic loss-of-function variants in the IYD gene cause hypothyroidism resulting from iodine wasting. We describe 8 patients (from 4 families in which the parents are first cousins) who are homozygous for a variant in IYD (including a novel missense deleterious variant, c.791C>T [P264L], in 1 family).

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Evaluating iodine deficiency and goiter in hilly areas of District Poonch Azad Jammu Kashmir.

Pak J Med Sci

August 2024

Muhammad Abbas, Department of Soil and Environmental Sciences, Faculty of Agriculture, University of Poonch Rawalakot, Rawalakot Poonch, Azad Jammu Kashmir, Pakistan.

Background & Objectives: Iodine deficiency is considered as a global challenge, even after decades of efforts to solve the issue. Our objective was to assess the iodine deficiency status and associated prevalence of goiter in population groups (school-age children and women) from rural areas of District Poonch, and to assess the determinants of iodine deficiency in the area.

Methods: Cross-sectional study was conducted in District Poonch Azad Jammu and Kashmir from 25 April 2022 to 30 June 2023.

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Considering the spectrum of benefits of breast milk feeding, determining the essential components of an infant's only food-mother's milk-seems justified, especially in the case of those whose deficiency (e.g., iodine) may result in developmental disorders.

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Copper-Mediated Synthesis of N-Aryl-Oxamic Acids.

Chemistry

October 2024

CNRS, Bordeaux INP, ISM, UMR 5255, University of Bordeaux, F-33400, Talence, France.

The Cu-catalyzed Ullmann-Goldberg cross-coupling between aryl iodides and oxamates is shown to afford the corresponding N-aryloxamates with yields ranging from moderate to excellent, when the oxamate precursor incorporates a bulky tertiary alkyl group effectively preventing product degradation under the strongly basic reaction conditions. The final oxamic acids are then generated through the acid hydrolysis of the oxamate in high yields. These acids were then converted into urethanes using PIDA under thermal conditions or a visible-light Fe-LMCT process.

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Refined linkage analysis of the sulphated marine polysaccharide fucoidan of Cladosiphon okamuranus with a focus on fucose.

Carbohydr Polym

October 2024

Institute of Chemistry of Renewable Resources, Department of Chemistry, University of Natural Resources and Life Sciences Vienna, Konrad-Lorenz-Straße 24, 3430 Tulln an der Donau, Austria. Electronic address:

Methylation followed by depolymerization and gas chromatography (GC) is an effective methodology for the linkage analysis of polysaccharides, including fucoidan, a sulphated algal polysaccharide. However, this sample material demands attention to experimental details to prevent aberrations in the analytical result. The use of deficient bases for methylation, the presence of water, analyte degradation during hydrolysis, and coelution of the target analytes during gas chromatography create doubts about published results.

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Aqueous zinc (Zn) iodine (I) batteries have emerged as viable alternatives to conventional metal-ion batteries. However, undesirable Zn deposition and irreversible iodine conversion during cycling have impeded their progress. To overcome these concerns, we report a dynamical interface design by cation chemistry that improves the reversibility of Zn deposition and four-electron iodine conversion.

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Expression and Function of Long Non-coding RNA in Endemic Cretinism.

Mol Neurobiol

July 2024

Chinese Centre for Disease Control and Prevention, Centre for Endemic Disease Control, Harbin Medical University, Heilongjiang Province 150081, Harbin City, People's Republic of China.

Endemic cretinism (EC) is one of the most severe iodine deficiency disorders, leading to typical symptoms such as neurodevelopmental impairments or mental deficits. In addition to environmental factors, the pathogenesis of its genetic contribution remains unclear. The study revealed the differential expression profiles of long non-coding RNA(lncRNA) and messenger RNA(mRNA) based on high-throughput RNA-seq.

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Background: With the implementation of the universal salt iodization, the iodine nutrition for children and adults has been appropriate, but pregnant women are still at risk of iodine deficiency. It is of great public health significance to explore the iodine status and knowledge, and influence factors and the appropriate health education methods among pregnant and lactating women.

Methods: From January 2022 to December 2023, at least 50 pregnant women and 50 lactating women were randomly selected from the resident population annually in 16 districts of Tianjin, North China.

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Thyroid Cancer in Regions Most Contaminated after the Chernobyl Disaster.

J Biomed Phys Eng

June 2024

Head of the Department of Endocrinology and Radioisotope Therapy, Military Institute of Medicine, Warsaw, Poland.

Exposure to ionizing radiation, especially during childhood, is a well-established risk factor for thyroid cancer. Following the 1986 Chernobyl nuclear power plant accident the total number of cases of thyroid cancer registered between 1991 and 2015 in males and females who were less than 18 years old exceeded 19,000 (in Belarus and Ukraine, and in the most contaminated oblasts of the Russian Federation). However, as indicated by the United Nations Scientific Committee on the Effects of Atomic Radiation the fraction of the incidence of thyroid cancer attributable to radiation exposure among the non-evacuated residents of the contaminated regions of Belarus, Ukraine and Russia is of the order of 0.

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Micronutrient intake and status in young vegans, lacto-ovo-vegetarians, pescatarians, flexitarians, and omnivores.

Eur J Nutr

October 2024

Department of Nutrition and Public Health, Faculty of Health and Sport Science, University of Agder, Universitetsveien 25, Kristiansand, 4630, Norway.

Purpose: Whether youth who follow plant-based diets in Nordic countries meet their dietary needs for micronutrients remains unclear. This study aims to evaluate micronutrient intake and status in Norwegian youth following vegan, lacto-ovo-vegetarian, pescatarian, flexitarian and omnivore diets.

Methods: Cross-sectional design, with healthy 16-to-24-year-olds (n = 165).

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Article Synopsis
  • * Conducted over six months with 318 participants, the research found a 6.6% prevalence of thyroid dysfunction, primarily hypothyroidism (5.3%) and a small percentage of hyperthyroidism (1.3%).
  • * The findings suggest a significant prevalence of gestational thyroid issues, underlining the importance of tailored antenatal care to improve early detection and management for better maternal and fetal health outcomes.
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We aimed to assess dietary iodine intake and sources in Zhejiang Province a decade after a reduction in iodine concentration in iodized salt. Three-day 24 h dietary recall and household weighing were used, complemented by "Chinese Food Composition" data. Household water and salt samples were collected from 5890 residents and analyzed.

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Article Synopsis
  • - Monocarboxylate transporter 8 (MCT8) is essential for transporting thyroid hormones T4 and T3 into cells, and mutations in its gene (SLC16A2) can cause Allan-Herndon-Dudley Syndrome (AHDS), a neurological disorder.
  • - Researchers created a new fluorescent assay to observe thyroid hormone uptake via MCT8, utilizing a dansyl-based probe that is selectively recognized by the transporter in living cells.
  • - The probe's specificity for MCT8 relies on a halogen bond interaction and the presence of a free carboxylic acid group; altering this group or adding a free amine disrupts recognition by MCT8.
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