11 results match your criteria: "Intertek Clinical Research Services[Affiliation]"
BDJ Open
July 2021
Intertek Clinical Research Services, Ellesmere Port, Cheshire, UK.
Objectives: To evaluate a 0.454% stannous fluoride/5% sodium tripolyphosphate (STP) toothpaste's ability to provide relief from dentinal hypersensitivity (DH) applied using 'focused brushing.'
Materials And Methods: In two randomised, examiner-blind, parallel-group studies, a SnF/STP toothpaste was applied by brushing two selected sensitive teeth before 1 min whole-mouth brushing, compared to 1 min whole-mouth brushing only, with a negative control toothpaste.
Am J Dent
February 2021
British American Tobacco R & D, Southampton, Hampshire, United Kingdom.
Purpose: To evaluate the effect of cigarette smoke, smokeless tobacco (e.g. snus), tobacco heating products (THP), electronic cigarettes (EC), and modern oral nicotine products on tooth staining.
View Article and Find Full Text PDFJ Dent
March 2021
Intertek Clinical Research Services, Ellesmere Port, Cheshire, United Kingdom. Electronic address:
Heliyon
September 2020
British American Tobacco, R&D, Southampton, Hampshire, SO15 8TL, UK.
Arch Oral Biol
November 2020
Intertek Clinical Research Services, Oaklands Office Park, Hooton Rd, Hooton, Cheshire, CH66 7NZ UK. Electronic address:
Objective: This exploratory, randomised, single-blind, crossover, study evaluated fluoride and calcium ion concentrations and pH following use of one of two 1450 ppm fluoride (NaF), 5% w/w KNO dentifrices: (1) test dentifrice (with cocamidopropyl betaine) with an orange juice (OJ) rinse; (2) test dentifrice with a deionized (DI) water rinse or (3) comparator dentifrice (with sodium lauryl sulphate and tetrasodium pyrophosphate) with an OJ rinse.
Design: Eighteen participants used their assigned dentifrice, rinsed with DI water, then expectorate was collected. Sixty min post-brushing, participants rinsed with OJ or DI water then expectorate was collected.
J Clin Periodontol
November 2019
Clinical Trials Unit (Periodontology), Bristol Dental School and Hospital, Bristol, UK.
Aim: To evaluate effects of a 0.454% stannous fluoride test toothpaste on dentine hypersensitivity (DH) applied by fingertip, then 3 days' brushing, versus a sodium monofluorophosphate-based control.
Materials And Methods: In three randomized clinical studies, DH was assessed using evaporative (Schiff scale) and tactile (Yeaple probe) stimuli.
Am J Dent
October 2018
British American Tobacco, R&D, Southampton, Hampshire, United Kingdom.
Purpose: To evaluate in vitro enamel sample discoloration following exposure to a scientific reference cigarette (3R4F) or emissions from next generation tobacco and nicotine products (NGPs) such as electronic cigarettes (EC) and tobacco heating products (THP).
Methods: Bovine enamel blocks (6.5 × 6.
Eur J Oral Sci
October 2018
Intertek Clinical Research Services, Hooton, Cheshire, UK.
This exploratory study investigated salivary concentrations of silicon, calcium, sodium, and phosphorous over a 60-min time period following the use of a calcium sodium phosphosilicate (CSPS)-containing dentifrice. Participants brushed with a dentifrice containing 5% (w/w) or 0% (w/w) CSPS or swilled with a slurry containing 5% (w/w) CSPS/glycerol. Saliva samples were collected before, and 2, 5, 15, and 60 min after, product use and were analysed using inductively coupled plasma optical emission spectroscopy.
View Article and Find Full Text PDFJ Dent
December 2017
Unilever Oral Care, Quarry Road East, Bebington, Wirral CH63 3JW, UK. Electronic address:
Objectives: To investigate the effects of a silica-based whitening toothpaste containing blue covarine on the colour of restorations in extracted human teeth.
Methods: Human extracted teeth were mounted in acrylic resin. A cavity was cut into the enamel surface and the specimen restored with either glass ionomer or composite dental materials.
BMC Oral Health
August 2016
GSK Consumer Healthcare, St Georges Avenue, Weybridge, Surrey, KT13 0DE, UK.
Background: Gingivitis can develop as a reaction to dental plaque. It can be limited by curtailing plaque build-up through actions including tooth brushing and the use of medicinal mouthwashes, such as those containing chlorhexidine digluconate (CHX), that can reach parts of the mouth that may be missed when brushing. This study aimed to compare dental stain control of twice-daily brushing with a sodium fluoride (NaF) dentifrice containing 67 % sodium bicarbonate (NaHCO3) or a commercially available NaF silica dentifrice without NaHCO3, while using a mouthwash containing 0.
View Article and Find Full Text PDFObjectives: Gingival bleeding following twice-daily use of 0.2% w/v chlorhexidine digluconate mouthrinse with and without alcohol (0.2% CHX-alcohol; 0.
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