11 results match your criteria: "Intertek Clinical Research Services[Affiliation]"

Objectives: To evaluate a 0.454% stannous fluoride/5% sodium tripolyphosphate (STP) toothpaste's ability to provide relief from dentinal hypersensitivity (DH) applied using 'focused brushing.'

Materials And Methods: In two randomised, examiner-blind, parallel-group studies, a SnF/STP toothpaste was applied by brushing two selected sensitive teeth before 1 min whole-mouth brushing, compared to 1 min whole-mouth brushing only, with a negative control toothpaste.

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Purpose: To evaluate the effect of cigarette smoke, smokeless tobacco (e.g. snus), tobacco heating products (THP), electronic cigarettes (EC), and modern oral nicotine products on tooth staining.

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Article Synopsis
  • The study compared the effects of two different toothpaste formulations on salivary fluoride and calcium ion concentrations following brushing and rinsing with orange juice or deionized water.
  • The test toothpaste (including cocamidopropyl betaine) showed higher fluoride levels at all time points compared to the comparator, particularly significant from 10 minutes post-brushing.
  • The research highlights that different toothpaste ingredients can affect fluoride retention in the mouth, suggesting that formulation excipients play a crucial role in oral health.
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Article Synopsis
  • Tobacco smoke can make walls and furniture look dirty over time because it stains things.
  • E-cigarettes and heated tobacco products create less harmful smoke compared to regular cigarettes, but how much they stain surfaces isn't completely known yet.
  • This study found that regular cigarettes caused a lot more staining on wallpaper and fabric compared to e-cigarettes and heated tobacco products, which barely changed the color at all.
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Objective: This exploratory, randomised, single-blind, crossover, study evaluated fluoride and calcium ion concentrations and pH following use of one of two 1450 ppm fluoride (NaF), 5% w/w KNO dentifrices: (1) test dentifrice (with cocamidopropyl betaine) with an orange juice (OJ) rinse; (2) test dentifrice with a deionized (DI) water rinse or (3) comparator dentifrice (with sodium lauryl sulphate and tetrasodium pyrophosphate) with an OJ rinse.

Design: Eighteen participants used their assigned dentifrice, rinsed with DI water, then expectorate was collected. Sixty min post-brushing, participants rinsed with OJ or DI water then expectorate was collected.

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Aim: To evaluate effects of a 0.454% stannous fluoride test toothpaste on dentine hypersensitivity (DH) applied by fingertip, then 3 days' brushing, versus a sodium monofluorophosphate-based control.

Materials And Methods: In three randomized clinical studies, DH was assessed using evaporative (Schiff scale) and tactile (Yeaple probe) stimuli.

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Purpose: To evaluate in vitro enamel sample discoloration following exposure to a scientific reference cigarette (3R4F) or emissions from next generation tobacco and nicotine products (NGPs) such as electronic cigarettes (EC) and tobacco heating products (THP).

Methods: Bovine enamel blocks (6.5 × 6.

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This exploratory study investigated salivary concentrations of silicon, calcium, sodium, and phosphorous over a 60-min time period following the use of a calcium sodium phosphosilicate (CSPS)-containing dentifrice. Participants brushed with a dentifrice containing 5% (w/w) or 0% (w/w) CSPS or swilled with a slurry containing 5% (w/w) CSPS/glycerol. Saliva samples were collected before, and 2, 5, 15, and 60 min after, product use and were analysed using inductively coupled plasma optical emission spectroscopy.

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Objectives: To investigate the effects of a silica-based whitening toothpaste containing blue covarine on the colour of restorations in extracted human teeth.

Methods: Human extracted teeth were mounted in acrylic resin. A cavity was cut into the enamel surface and the specimen restored with either glass ionomer or composite dental materials.

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Background: Gingivitis can develop as a reaction to dental plaque. It can be limited by curtailing plaque build-up through actions including tooth brushing and the use of medicinal mouthwashes, such as those containing chlorhexidine digluconate (CHX), that can reach parts of the mouth that may be missed when brushing. This study aimed to compare dental stain control of twice-daily brushing with a sodium fluoride (NaF) dentifrice containing 67 % sodium bicarbonate (NaHCO3) or a commercially available NaF silica dentifrice without NaHCO3, while using a mouthwash containing 0.

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Objectives: Gingival bleeding following twice-daily use of 0.2% w/v chlorhexidine digluconate mouthrinse with and without alcohol (0.2% CHX-alcohol; 0.

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