91 results match your criteria: "International Vision Correction Research Centre IVCRC[Affiliation]"

[Duet procedure to achieve reversible trifocality].

Ophthalmologe

October 2020

International Vision Correction Research Centre (IVCRC), Universitäts-Augenklinik Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland.

The functional results and the occurrence of side effects (especially photic phenomena) for multifocal intraocular lenses (IOL) are difficult to predict. Furthermore, in the course of life patients can develop diseases in which a multifocal optic would be a disadvantage. In these cases exchange of the IOL is the only treatment option.

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Implantation of a small-aperture intraocular lens and a partial aniridia implant in eyes with traumatic iris defects.

Am J Ophthalmol Case Rep

June 2020

David J. Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany.

Purpose: To report the clinical outcomes after implantation of a small-aperture intraocular lens (IOL) and a partial aniridia ring in three patients with traumatic iris defects.

Observations: The corrected distance visual acuity (CDVA), irregular astigmatism, and glare improved in all patients. In one patient, the monocular defocus curve showed a visual acuity (VA) of 0.

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Laboratory evaluation of the optical properties of two extended-depth-of-focus intraocular lenses.

BMC Ophthalmol

February 2020

Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Pyeong-Dong, Jongno-Gu, Seoul, Republic of Korea.

Background: To experimentally compare the optical performance of two different Extended-Depth-of-Focus (EDOF) intraocular lenses (IOLs) using a standardized optical bench set-up.

Methods: In this experimental study, following IOLs were assessed: the TECNIS® Symfony ZXR00 (Johnson&Johnson, Santa Ana, USA) and the AT LARA 829MP (Carl Zeiss Meditec, Jena, Germany) IOLs. The through-focus modulation transfer function (MTF) values were measured at a spatial frequency of 50 lp/mm and at aperture sizes of 2, 3, and 4.

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Ray propagation imaging and optical quality evaluation of different intraocular lens models.

PLoS One

April 2020

The David J. Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany.

Purpose: Ray propagation visualization and optical performance analysis of four different intraocular lenses (IOLs).

Methods: In this laboratory study, four IOLs with different optical designs were assessed: a monofocal AcrySof IQ SN60WF [Alcon], a diffractive-refractive bifocal AcrySof IQ Restor SN6AD1 [Alcon], a diffractive trifocal AcrySof IQ PanOptix TFNT00 [Alcon], and a diffractive extended-depth-of-focus (EDOF) Symfony ZXR00 [Johnson&Johnson]. An experimental set-up with a water bath containing 0.

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Background: To evaluate the clinical outcomes of extended depth of focus (EDOF) and monofocal intraocular lenses (IOLs) that share identical aspheric platform and compare their visual acuity tolerance to postoperative refractive errors.

Methods: This non-randomized, prospective comparative study included 120 eyes undergoing cataract surgery with implantation of either Tecnis ZCB00 IOL (Abbott Medical Optics Inc., Santa Ana, CA) (monofocal group: 60 eyes of 30 patients) or Tecnis Symfony IOL (Abbott Medical Optics, Inc.

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[Duet Procedure in High Myopia to Achieve Reversible Multifocality].

Klin Monbl Augenheilkd

August 2020

International Vision Correction Research Centre (IVCRC) und David J Apple International Laboratory for Ocular Pathology, Universitätsklinikum Heidelberg.

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Purpose: To compare measurements of anterior and posterior keratometric values, using a color light-emitting diode corneal topographer and a dual rotating Scheimpflug-Placido topographer.

Methods: Anterior and posterior corneal index measurements were performed using a color light-emitting diode corneal topographer (Cassini) and a dual rotating Scheimpflug-Placido topographer (Galilei G4) and then compared. The paired -test, intraclass correlation coefficients (ICCs), and Bland-Altman plots were used to evaluate the agreement between measurements.

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Lights and darks of a picture. The life of Giovanni Francesco Barbieri, "il Guercino" - the squinter.

Strabismus

March 2019

a International Vision Correction Research Centre (IVCRC), Department of Ophthalmology , University of Heidelberg, Heidelberg.

Purpose: To be cross-eyed is a wide-spread dysfunction of the eye and squinting is currently regarded as unattractive. However, in ancient times, societies saw squinting as a sign of piety or even beauty. Even Venus was depicted heterophoric quite often.

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[In Vitro Evaluation of the Optical Quality of Segmental Refractive Multifocal Intraocular Lenses].

Klin Monbl Augenheilkd

August 2019

International Vision Correction Research Centre (IVCRC) und David J Apple International Laboratory for Ocular Pathology, Univ.-Augenklinik Heidelberg.

Objectives: In customised patient care, it is important to know the optical quality of different intraocular lenses (IOL). In this study, the optical quality of three segmental intraocular lenses were compared.

Materials And Methods: The LENTIS Comfort LS-313 MF15, LENTIS Mplus X LS-313 MF30 and LENTIS High Add IOL LS-313 MF80 (Oculentis, Berlin, Germany) with a far power of + 21 D were analysed at the optical bench OptiSpheric IOL PRO (Trioptics GmbH, Wedel, Germany).

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To analyse the optical quality of diffractive multifocal intraocular lenses (IOLs) with different near additions in a laboratory study. We analysed the AcrySof IQ ReSTOR + 2.5 D SV25T0 (Alcon Laboratories inc.

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[Optical quality of three trifocal intraocular lens models : An optical bench comparison].

Ophthalmologe

January 2018

David J Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Universitäts-Augenklinik Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Deutschland.

Background: Knowledge of the optical quality of different trifocal intraocular lenses (IOL) is important in customized patient care.

Objective: Different trifocal IOL were compared regarding their optical quality.

Materials And Methods: We analyzed the FineVision (PhysIOL, Liège, Belgium), the AT LISA tri 839MP (Zeiss, Oberkochen, Germany), and the AcrySofIQ PanOptix (Alcon, Fort Worth, TX, USA) with a power of +21D for the distance using the OptiSpheric IOL PRO optical bench (Trioptics, Wedel, Germany).

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Purpose: Meibomian gland disease is generally accepted as the leading cause for evaporative dry eye disease (DED). In a previous study, perfluorohexyloctane, a semifluorinated alkane, has been demonstrated to significantly increase tear film breakup time and to reduce corneal fluorescein staining in patients with evaporative DED, thereby vastly reducing dry eye-related symptoms. This study was set up to evaluate perfluorohexyloctane in a larger population of patients with Meibomian gland dysfunction.

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Clinical outcomes after implantation of a toric intraocular lens with a transitional conic toric surface.

Br J Ophthalmol

March 2018

Department of Ophthalmology, International Vision Correction Research Centre (IVCRC), University of Heidelberg, Heidelberg, Germany.

Purpose: To evaluate the postoperative outcomes after implantation of a hydrophilic toric intraocular lens (tIOL) with a transitional conic toric surface in patients with astigmatism undergoing refractive lens exchange (RLE) or cataract surgery.

Methods: In this monocentric study, clinical outcomes following implantation of the hydrophilic Precizon toric IOL model 565 (Ophtec) were analysed. For intraoperative axis alignment, the Verion Image Guided System was used.

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In vitro optical quality measurements of three intraocular lens models having identical platform.

BMC Ophthalmol

June 2017

David J. Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany.

Background: With recent advances in technology and introduction of new intraocular lens (IOL) models, surgeons today have the opportunity to choose from various optical designs, which can influence the postoperative quality of vision. In our laboratory study, we compared the optical quality of three different IOLs that use the identical platform and are produced by the same manufacturer. The study included two diffractive multifocal IOLs, a bifocal and a trifocal one, as well as a monofocal IOL.

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In vitro comparative optical bench analysis of a spherical and aspheric optic design of the same IOL model.

BMC Ophthalmol

February 2017

David J Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg, 69120, Germany.

Background: To analyse objective optical properties of the spherical and aspheric design of the same intraocular lens (IOL) model using optical bench analysis.

Methods: This study entailed a comparative analysis of 10 spherical C-flex 570 C and 10 aspheric C-flex 970 C IOLs (Rayner Intraocular Lenses Ltd., Hove, UK) of 26 diopters [D] using an optical bench (OptiSpheric, Trioptics, Germany).

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[Opacification of a hydrophilic acrylic intraocular lens after DMEK : A material analysis].

Ophthalmologe

September 2017

David J Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Universitäts-Augenklinik Heidelberg, Heidelberg, Deutschland.

Objective: Calcification of a hydrophilic intraocular lens (IOL) is a rare complication. We report on the analysis of an opacified IOL, which was explanted 2 years after Descemet membrane endothelial keratoplasty (DMEK), using light and scanning electron microscopy, X‑ray spectroscopy and investigations on the optical bench.

Methods: In October 2012 a patient with pseudophakic keratopathy and Fuchs endothelial dystrophy underwent DMEK with double rebubbling.

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Purpose: The aim of this study was to evaluate the duration of the preoperative examination and patient comfort in measurements with an Image Guided System (Verion, Alcon), which is used for the calculation and intraoperative alignment of toric intraocular lenses, in comparison to established keratometry devices.

Patients And Methods: In a prospective, monocentric, open, ethics committee controlled study, 150 eyes of 150 ophthalmologically healthy volunteers were examined by a single examiner. Three measurements were performed with the Verion Image Guided System and - for comparison - one measurement each with IOLMaster 500, Lenstar LS900 and Pentacam HR.

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Impact of Indocyanine Green Concentration, Exposure Time, and Degree of Dissolution in Creating Toxic Anterior Segment Syndrome: Evaluation in a Rabbit Model.

J Ophthalmol

August 2016

David J Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, Republic of Korea.

Purpose. To investigate the role of indocyanine green (ICG) dye as a causative material of toxic anterior segment syndrome (TASS) in an experimental rabbit model. Method.

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The objective of this study was to evaluate postoperative clinical outcomes of photorefractive keratectomy (PRK) using different ablation frequencies. In this prospective, contralateral eye study, 56 eyes of 28 patients with myopia or myopic astigmatism were included. PRK was performed using the MEL90 excimer laser system (Carl Zeiss Meditec, Germany).

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In Vivo Imaging of Intraocular Fluidics in Vitrectomized Swine Eyes Using a Digital Fluoroscopy System.

J Ophthalmol

April 2016

David J Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany; Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, 29 Saemunan-ro, Jongno-gu, Seoul 03181, Republic of Korea.

Purpose. To describe the characteristics of intraocular fluidics during cataract surgery in swine eyes with prior vitrectomy. Methods.

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Long-term outcomes of intrastromal femtosecond laser presbyopia correction: 3-year results.

Br J Ophthalmol

November 2016

International Vision Correction Research Centre (IVCRC) and David J Apple International Laboratory of Ophthalmic Pathology, Department of Ophthalmology, University of Heidelberg, Heidelberg, Germany.

Background/aims: To analyse visual outcomes and corneal changes 3 years after intrastromal femtosecond laser presbyopia treatment.

Methods: In a prospective, unicentric clinical trial, 25 presbyopic patients received INTRACOR treatment (Technolas femtosecond laser) on their non-dominant eye. Examinations were performed preoperatively as well as 1, 24 and 36 months postoperatively and included refraction, near, intermediate and distance visual acuity tests, reading speed, corneal topography, stray light measurement, endothelial cell count and slit-lamp examination.

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Proteomics of vitreous in neovascular age-related macular degeneration.

Exp Eye Res

May 2016

Department of Ophthalmology, University of Heidelberg, Germany; David J Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Heidelberg, Germany; Department of Ophthalmology, University of Southern California, Los Angeles, CA, USA. Electronic address:

Neovascular age-related macular degeneration (nAMD) has been described as a predominantly inflammatory and proangiogenic retino-choroidal disease. Vitreous humor (VH) is the adjacent and accessible compartment which, due to the vicinity to the retina, might best represent changes of protein-based mediators of nAMD. The aim of this clinical-experimental study was to analyze the nAMD associated VH proteome of previously untreated patients whilst taking different groups of nAMD into account, based on their clinical presentation (clinical diagnosis groups).

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Optical and material analysis of opacified hydrophilic intraocular lenses after explantation: a laboratory study.

BMC Ophthalmol

November 2015

David J Apple International Laboratory for Ocular Pathology and International Vision Correction Research Centre (IVCRC), Department of Ophthalmology, University of Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

Background: The opacification of hydrophilic intraocular lenses (IOLs) is a very rare complication in terms of absolute numbers. We report on the analyses of opacified Euromaxx ALI313Y and ALI313 IOLs (Argonoptics, Germany) using light and scanning electron microscopy, X-ray spectroscopy and optical bench analysis.

Methods: Opacified Euromaxx ALI313Y and ALI313 IOLs were explanted after patients presented with a decrease in visual acuity.

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