Dielectrophoresis of Amyloid-Beta Proteins as a Microfluidic Template for Alzheimer's Research.

We employed dielectrophoresis to a yeast cell suspension containing amyloid-beta proteins (Aβ) in a microfluidic environment. The Aβ was separated from the cells and characterized using the gradual dissolution of Aβ as a function of the applied dielectrophoretic parameters. We established the gradual dissolution of Aβ under specific dielectrophoretic parameters.

Genomic analysis of methicillin-resistant Staphylococcus aureus strain SO-1977 from Sudan.

Background: Methicillin-resistant Staphylococcus aureus (MRSA) is known as a leading cause of morbidity and mortality. Investigation of the MRSA's virulence and resistance mechanisms is a continuing concern toward controlling such burdens through using high throughput whole Genome Sequencing (WGS) and molecular diagnostic assays. The objective of the present study is to perform whole-genome sequencing of MRSA isolated from Sudan using Illumina Next Generation Sequencing (NGS) platform.

May Measurement Month 2017: an analysis of blood pressure screening in Sudan-Northern Africa and Middle East.

Elevated blood pressure (BP) is a growing burden worldwide, leading to over 10 million deaths each year. Sudan has the second highest prevalence of hypertension in North Africa. One in four people with a non-communicable disease has hypertension.

Novel magnetically separable of FeO/AgPO@WO nanocomposites for enhanced photocatalytic and antibacterial activity against Staphylococcus aureus (S. aureus).

Background: Iron oxide nanocomposites have received a great attention for their application in various fields like physics, medicine, biology, and material science etc., due to their unique properties, such as magnetism, electrical properties, small size, biocompatibility and low toxicity.

Methods: FeO/AgPO@WO nanocomposites with different weight percent of AgPO were successfully prepared through fabricated AgPO/FeO with WO via in situ fabrication method, electrospinning involved precursor solution preparation and spinning to enhance photocatalyst performance under simulated sunlight for the degradation of methylene blue (MB) and antibacterial activity against Staphylococcus aureus (S.

Evaluation of undergraduate psychiatric teaching in Sudan.

Development of an undergraduate psychiatric teaching programme and curriculum is a challenge in the current atmosphere of increasing knowledge and vast literature. However, the curriculum remains the cornerstone for future doctors' development and career. Doctors need to have the abilities to recognise, assess and manage common psychiatric conditions presenting at different levels of health services.

Sensitive and selective colorimetric nitrite ion assay using silver nanoparticles easily synthesized and stabilized by AHNDMS and functionalized with PABA.

Nitrite ions (NO ), as one of the important inorganic anions, exhibit considerable effects towards the environment and human health. Moreover, over intake of this anion may cause dangerous diseases. Herein, we successfully fabricated silver nanoparticles (AgNPs) using 4-amino-5-hydroxynaphthalene-2, 7-disulphonic acid monosodium salt (AHNDMS) and functionalized them with -aminobenzoic acid (PABA), and used the functionalised AgNPs as a sensitive and selective colorimetric sensor for nitrite ions.

A simple yet sensitive colorimetric nitrite ions assay based on diazotization with p‑Aminobenzoic and coupling with phloroglucinol in acidic medium.

Immoderate intake of nitrite (NO) is deleterious human health and may result in causing dangerous diseases. In this study, nitrite detection system was successfully fabricated based on a unique diazo-coupling reaction of p‑Aminobenzoic acid (PABA) and phloroglucinol (1, 3, 5‑trihydroxybenzene). Upon the presence of NO in an acid medium, p‑Aminobenzoic acid could not only form diazonium ion easily but also couple with p‑Aminobenzoic acid, and results forming yellow water-soluble azo dye that shows maximum absorption at 434 nm.

Are visual processes causally involved in "perceptual simulation" effects in the sentence-picture verification task?

Many studies have shown that sentences implying an object to have a certain shape produce a robust reaction time advantage for shape-matching pictures in the sentence-picture verification task. Typically, this finding has been interpreted as evidence for perceptual simulation, i.e.

Prevalence of dengue fever virus antibodies and associated risk factors among residents of El-Gadarif state, Sudan.

Background: Dengue fever, caused by dengue virus (DENV), has become one of the most important mosquito-borne viral diseases with a steady rise in global incidence, including the Sudan. Sporadic cases and frequent acute febrile illness outbreaks, compatible with Dengue fever, have been reported in El-Gadarif State, Sudan. However, diagnosis was based almost exclusively on clinical signs without confirmatory laboratory investigations.

Cross sectional study to determine chloroquine resistance among clinical isolates from Khartoum, Sudan.

 Malaria continues to present a global health threat; the World Health Organization (WHO) reported 214 million cases of malaria by the year 2015 with a death rate of 438000. Sudan is endemic to malaria with over 95% of malaria cases due to . Chloroquine is a well-established drug in the treatment of malaria although its use has declined since its introduction as the drug of choice in treatment of malaria in Sudan.

Prevalence and Associated Symptoms of Infection among Schoolchildren in Kassala State, East of Sudan.

This study aimed to determine the prevalence of infections among schoolchildren and investigate the associations between seropositivity and existence of gastrointestinal symptoms. . A prospective cross-sectional study was conducted during a period from January to December 2012 at Kassala state, east of Sudan.

Developing a risk prediction model for breast cancer: a Statistical Utility to Determine Affinity of Neoplasm (SUDAN-CA Breast).

Background: Breast cancer risk prediction models are widely used in clinical settings. Although most of the well-known models were designed based on data collected from western population, yet they have been utilized for surveillance purposes in many limited-resource countries. Given the genetic variations in risk factors that exist between different races, we therefore aimed to develop and validate a tool for breast cancer risk assessment among Sudanese women.

Assessing healthcare professional knowledge, attitudes, and practices on hypertension management. Announcing a new World Hypertension League resource.

To assist hypertension control programs and specifically the development of training and education programs on hypertension for healthcare professionals, the World Hypertension League has developed a resource to assess knowledge, attitudes, and practices on hypertension management. The resource assesses: (1) the importance of hypertension as a clinical and public health risk; (2) education in national or international hypertension recommendations; (3) lifestyle causes of hypertension; (4) measurement of blood pressure, screening, and diagnosis of hypertension; (5) lifestyle therapy counseling; (6) cardiovascular risk assessment; (7) antihypertensive drug therapy; and (8) adherence to therapy. In addition, the resource assesses the attitudes and practices of healthcare professionals for task sharing/shifting, use of care algorithms, and use of registries with performance reporting functions.

Integration of phytochemicals and phytotherapy into cancer precision medicine.

Concepts of individualized therapy in the 1970s and 1980s attempted to develop predictive in vitro tests for individual drug responsiveness without reaching clinical routine. Precision medicine attempts to device novel individual cancer therapy strategies. Using bioinformatics, relevant knowledge is extracted from huge data amounts.

Impact of clinical pharmacist intervention in anticoagulation clinic in Sudan.

Background Many trials have compared anticoagulation management provided by a pharmacist led anticoagulation clinic versus usual physician care showing the role for clinical pharmacist in the management of anticoagulant therapy, and demonstrating excellent outcomes. In Sudan, there is no published research evaluating the role of pharmacist in providing pharmaceutical care for patients taking warfarin. Objective The objective of the study is to assess the role of clinical pharmacist intervention in warfarin patients compared to usual medical care.

Draft Genome Sequence of a Multidrug-Resistant Strain Isolated from a Patient with a Urinary Tract Infection in Khartoum, Sudan.

infection is difficult to treat due to the presence of antibiotic resistance determinants. Here, we report the genome sequence of a multidrug-resistant strain isolated from a patient with a urinary tract infection in 2015.

Reinventing the political role of health professionals in conflict prevention & reconciliation: the Sudanese model.

Given the persistent recurrence of armed conflict, influential actors owe it to the affected communities to take action. The legitimacy of health professionals to mitigate the effects of conflict relates to their ability to save lives and address the physical and mental consequences of armed conflict during which thousands of lives may be lost. Medical professionals have unique and potentially far-reaching skills.

Factors Delaying Presentation of Sudanese Breast Cancer Patients: an Analysis Using Andersen's Model.

Purpose: A multicenter, observational, cross-sectional study was conducted to assess factors delaying presentation of breast cancer cases.

Materials And Methods: Data were collected from a pair of highly specialized referral centers, both located in the center of the Sudanese capital, Khartoum. For a total of 153 eligible respondents, durations of delay, clinicodemographic factors and reasons of referral were collected from our respondents through self-administered questionnaires.

The Power of Implicit Social Relation in Rating Prediction of Social Recommender Systems.

The explosive growth of social networks in recent times has presented a powerful source of information to be utilized as an extra source for assisting in the social recommendation problems. The social recommendation methods that are based on probabilistic matrix factorization improved the recommendation accuracy and partly solved the cold-start and data sparsity problems. However, these methods only exploited the explicit social relations and almost completely ignored the implicit social relations.

Airway foreign bodies: A critical review for a common pediatric emergency.

Background: Airway foreign bodies (AFBs) is an interdisciplinary area between emergency medicine, pediatrics and otolaryngology. It is a life-threatening condition that is not infrequently seen; however, it is poorly covered in medical literature. Accidental aspiration of an element into airways is a widespread clinical scenario among children under 3 years, predominantly males.

Low Seroprevalence Indicates Vulnerability of Eastern and Central Sudan to Infection with Chikungunya Virus.

Outbreaks of infections with chikungunya virus (CHIKV) have previously been reported from Sudan but the prevalence in the general population is unknown. We investigated the seroprevalence of CHIKV infection in 379 serum samples from patients with fever in the outpatient clinics of three hospitals in eastern and central Sudan. The seroprevalence was 1.

Factors associated with antenatal and delivery care in Sudan: analysis of the 2010 Sudan household survey.

Background: Every day, globally approximately a thousand women and girls needlessly die as a result of complications during pregnancy, childbirth or the 6 weeks following delivery. The majority of maternal deaths are avoidable and could be prevented with proven interventions to prevent or manage complications during pregnancy and child birth. The aim of this study was to examine factors associated with underutilization of maternal health services in Sudan.

Crystal structure of 4-methyl-N-[(4-methyl-pyridin-2-yl)carbamo-thioyl]-benzamide.

In the title compound, C15H15N3OS, the dihedral angle between the planes of the benzene and pyridine rings is 26.86 (9)°. Intra-molecular N-H⋯O and C-H⋯S hydrogen bonds both generate S(6) rings.

Examination frequency and population dose from medical X-ray examinations in Sudan in 2010.

This study was performed to estimate examination frequency and collective and per caput effective doses arising from medical X-ray procedures in Sudan, 2010. Information was collected from 30 hospitals performing radiography, computed tomography (CT), fluoroscopy and interventional radiology (IR) procedures. The estimated annual number of examinations was 33 million radiographic X-ray procedures (99 %), 0.

The prevalence and factors affecting attention deficit hyperactivity disorder among school children in Khartoum State.

Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children, characterized by age-inappropriate features of inattention, hyperactivity and impulsivity or both. The aim of this study is to determine the prevalence and socio demographic correlates of ADHD symptoms in general basic schoolchildren. A cross-sectional study conducted in Khartoum North.