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Antipsychotic polypharmacy in children and adolescents at discharge from psychiatric hospitalization.
Pharmacotherapy
August 2014
Department of Pharmacy, Intermountain Primary Children's Hospital, Salt Lake City, Utah; Division of Pharmacy, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Study Objective: Antipsychotic polypharmacy-the use of more than one antipsychotic concomitantly-has increased in children and adolescents and may be associated with increased adverse effects, nonadherence, and greater costs. Thus, we sought to examine the demographic and clinical characteristics of psychiatrically hospitalized children and adolescents who were prescribed antipsychotic polypharmacy and to identify predictors of this prescribing pattern.
Design: Retrospective medical record review.