62 results match your criteria: "Interdisciplinary Center "Smell and Taste"[Affiliation]"
Rhinology
April 2021
Interdisciplinary Centre Smell and Taste, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.
Purpose: Although neglected by science for a long time, the sense of olfaction has received increasing attention from research areas including psychology, neuroscience, clinical medicine and nutrition. With the rise of psychophysical and neuroimaging re- search into olfaction, psychometric tools (e.g.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
February 2021
Department of Otorhinolaryngology, Interdisciplinary Center Smell and Taste, Medical Faculty Carl Gustav Carus, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Purpose: The diagnosis of olfactory dysfunction is mainly based on psychophysical measurements. The aim of the current study was to investigate how well the olfactory functional magnetic resonance imaging (fMRI) can effectively distinguish between normosmic people and subjects with olfactory dysfunction.
Methods: Thirty-eight participants were recruited for the study.
Neurosci Lett
September 2020
Interdisciplinary Center on Smell and Taste, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.
The trace amine-associated receptors (TAARs) are a second class of olfactory receptors in humans. They are activated by volatile amines, including pheromone-like odors. However, in humans the neural processing of TAAR-associated signals is not known.
View Article and Find Full Text PDFActa Otolaryngol
June 2020
Interdisciplinary Center Smell and Taste, Department of Otorhinolaryngology, Medical Faculty Carl Gustav Carus, Dresden, Germany.
Odor identification is related to odor naming, which is more of a verbal than an olfactory sensory task. Linguistic functions in right-handers are typically lateralized to the left hemisphere of the brain and the olfactory processing happens predominantly ipsilaterally to the stimulated side. Re-investigate side-related effect in healthy right-handed people with a larger sample size and investigate the influence of age or gender on the odor identification lateralization effect.
View Article and Find Full Text PDFLaryngoscope
January 2021
Interdisciplinary Center for Smell and Taste, Department of Otorhinolaryngology, Dresden, Germany.
Objectives/hypothesis: The association between smoking and olfactory loss remains a conundrum. Prior studies have found negative and positive effects of smoking on olfactory function in the general population. However, smoking cessation seems to improve both rated and measured olfactory function.
View Article and Find Full Text PDFBrain Res
March 2020
Interdisciplinary Center Smell and Taste, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.
Repeated sensory exposure through frequent consumption of certain foods leads to changes in the processing of sensory cues. We investigated the influence of frequent minty chewing gum consumption on the neurobehavioral processing of intranasal trigeminal and olfactory stimuli. fMRI responses to a trigeminal minty odor (L-menthol), a non-trigeminal minty odor (L-carvone), and a non-trigeminal non-minty odor (strawberry) were assessed in 29 young adults (mean age = 23 years, SD = 4.
View Article and Find Full Text PDFNeuroimage
March 2020
Interdisciplinary Center on Smell and Taste, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.
Taste sensitivity relates to food preferences and macronutrients intake. The current study investigated whether the neural responses to food odors varied in sensory quality (sweet or non-sweet) and their associations with macronutrient content (high- or low-fat) in young healthy participants varied in sweet taste sensitivity. Thirty-eight participants were assessed for their sensitivity to sucrose solutions using a modified "taste strip" test.
View Article and Find Full Text PDFBrain Topogr
January 2020
Department of Otorhinolaryngology, Interdisciplinary Center Smell and Taste, TU Dresden, Dresden, Germany.
The original version of this article unfortunately contained a mistake. The spelling of the Yoshi Akshita name was incorrect. The correct name should be Joshi Akshita The original article has been corrected.
View Article and Find Full Text PDFJ Neurol
January 2020
Department of Neurology, Movement Disorders Center, Institute of Neurology, Azienda Ospedaliero Universitaria (A.O.U.), University of Cagliari, Cagliari, Italy.
The role of specific sex-related patterns in olfactory dysfunctions of Parkinson's disease (PD) patients is unclear. The aim of this study was to assess the presence of specific sex-related patterns in olfactory dysfunctions excluding the possibility of confounding effects in patients with Parkinson's disease. One hundred and sixty-eight participants (99 PD patients and 69 controls) were enrolled and evaluated using Sniffin' Sticks Extended test (SSET).
View Article and Find Full Text PDFBrain Topogr
November 2019
Department of Otorhinolaryngology, Interdisciplinary Center Smell and Taste, TU Dresden, Dresden, Germany.
Olfactory dysfunctions affect a larger portion of population (up to 15% with partial olfactory loss, and 5% with complete olfactory loss) as compared to other sensory dysfunctions (e.g. auditory or visual) and have a negative impact on the life quality.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
October 2019
Interdisciplinary Center Smell and Taste, Department of Otorhinolaryngology, Medical Faculty Carl Gustav Carus, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Purpose: Eating-related problems are among the most frequent issues in olfactory impairment, causing a noticeable loss of quality of life for some of the affected persons. To what extent olfactory dysfunction impacts on the sensory perception of food is less explored. The aim of the present study was to examine the impact of olfactory dysfunction on the perception of food aromas, as well as the perception of the "basic tastes" salty, sour, sweet, and bitter.
View Article and Find Full Text PDFORL J Otorhinolaryngol Relat Spec
May 2020
Interdisciplinary Smell and Taste Center, Technical University of Dresden, Dresden, Germany.
Laryngoscope
May 2020
Interdisciplinary Center of Smell and Taste, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.
Objective: Functional magnetic resonance imaging (fMRI) is a non-invasive neuroimaging technique widely used in olfactory research. During a typical fMRI olfactory block-design, one functional "run" refers to a combination of multiple blocks with continuous brain image acquisition. The current study investigated the length of functional runs on odor-induced brain response signals (blood oxygen level dependent [BLOD]) within the primary and key secondary olfactory areas.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
June 2019
Interdisciplinary Center Smell and Taste, Department of Otorhinolaryngology, Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany.
Purpose: Few studies have investigated the correlation between chemosensory function (trigeminal and olfactory) and nasal volume in humans, even though nasal anatomy is crucial for the sense of smell. Aim of this study was to evaluate these correlations in normosmic subjects.
Methods: Two hundred and fifty-six healthy volunteers (age range 19-69 years) participated.
Eur Arch Otorhinolaryngol
March 2019
Department of Otorhinolaryngology, University Hospital, University of Basel, Basel, Switzerland.
Purpose: The present study aimed to explore if food perception can be influenced by sound mastication level when the external ear canal was occluded.
Methods: Fifty-nine adults (38 women) with normal hearing, smell, and taste participated in the study. They tasted five crispy and five soft food items over two sessions: one with and one without an earplug inserted in the external ear canal.
Brain Res
April 2019
Interdisciplinary Center "Smell and Taste", Department of Otorhinolaryngology, TU Dresden, Fetscherstrasse 74, 01307 Dresden, Germany.
Objective: Methods based on electroencephalography (EEG) are used to evaluate brain responses to odors which is challenging due to the relatively low signal-to-noise ratio. This is especially difficult in patients with olfactory loss. In the present study, we aim to establish a method to separate functionally anosmic and normosmic individuals by means of recordings of olfactory event-related potentials (OERP) using an automated tool.
View Article and Find Full Text PDFNutrients
December 2018
Centre for Nutrition and Food Sciences, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St. Lucia QLD 4072, Australia.
Eating behaviour in humans is a complex trait that involves sensory perception. Genetic variation in sensory systems is one of the factors influencing perception of foods. However, the extent that these genetic variations may determine food choices in a real meal scenario warrants further research.
View Article and Find Full Text PDFNeuroscience
December 2018
Interdisciplinary Smell and Taste Lab, TU Dresden, Dresden, Germany.
Functional plasticity of the adult brain is well established. Recently, the structural counterpart to such plasticity has been suggested by neuroimaging studies showing experience-dependent differences in gray matter (GM) volumes. Within the primary and secondary olfactory cortices, reduced GM volumes have been demonstrated in patients with olfactory loss.
View Article and Find Full Text PDFJ Neurol
August 2018
Interdisciplinary Center Smell and Taste, Department of Otorhinolaryngology, Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany.
Although Parkinson's disease (PD) is usually considered as a movement disorder, it is strongly associated with non-motor symptoms (NMS), including smell and taste dysfunctions, cognitive impairment, apathy, fatigue, and autonomic dysregulation. Olfactory deficit is considered the most common NMS in PD preceding the motor symptoms for years. The aim of this study was to investigate olfactory function, cognitive impairment, apathy, and fatigue in patients with PD in comparison with healthy controls, and subsequently to analyse the correlations between these NMS and motor symptoms severity in subjects with PD.
View Article and Find Full Text PDFNeuroscience
July 2018
Interdisciplinary Center on Smell and Taste, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.
There is a large inter-individual variation for umami taste perception. However the neural mechanism for this variability is not well understood. This study investigated brain responses to umami and salty taste among individuals with different umami identification abilities and the effect of repeated oral umami exposure on umami identification and neural processing of taste perceptions.
View Article and Find Full Text PDFJ Neurotrauma
November 2018
1 Interdisciplinary Center on Smell and Taste, Department of Otorhinolaryngology, TU Dresden , Dresden, Germany .
Olfactory loss and traumatic brain injury (TBI) both lead to anatomical brain alterations in humans. Little research has been done on the structural brain changes for TBI patients with olfactory loss. Using voxel-based morphometry, the gray matter (GM) density was examined for 22 TBI patients with hyposmia, 24 TBI patients with anosmia, and 22 age-matched controls.
View Article and Find Full Text PDFRhinology
June 2018
Interdisciplinary Center on Smell and Taste, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.
Background: Cross-modal chemosensory dysfunction between olfaction and gustation is not well known.
Methodology: 180 participants were classified into three groups (60 with olfactory dysfunction, 60 with gustatory dysfunction and 60 healthy controls without chemosensory dysfunction). Olfactory functions were obtained with Sniffin Sticks; gustatory function was measured by suprathreshold gustatory stimuli (taste sprays) and a quasi-threshold measure of taste function (taste strips) for five taste qualities (sweet, salty, sour, bitter and umami).
J Neurol
June 2017
Department of Otorhinolaryngology, Interdisciplinary Center "Smell and Taste", TU Dresden, Fetscherstr. 74, 01307, Dresden, Germany.
Early diagnosis and timely treatment of Parkinson's disease are essential factors to provide these patients with a longer period of a better quality of life. Olfactory loss is among the first non-motor symptoms of the disease; however, in light of the many causes of smell loss, it is a very unspecific biomarker and should only be used as part of a diagnostic test battery. In this study, we investigated the olfactory response in 71 subjects, consisting of Parkinson's disease patients, hyposmic and anosmic patients of other causes, and normosmic individuals searching for sensitive, distinct biomarkers for which we used scalp event-related 64-channel electroencephalography and psychophysical tests.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
July 2017
Department of Otorhinolaryngology, Interdisciplinary Center for Smell and Taste, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Vitamin A plays a decisive role in the regeneration of olfactory receptor neurons. In this retrospective study we investigated the effectiveness of topical vitamin A in patients with post-infectious and posttraumatic smell disorders. Retrospective cohort.
View Article and Find Full Text PDFEur Arch Otorhinolaryngol
July 2017
Department of Otorhinolaryngology, Smell and Taste Clinic, Interdisciplinary Center Smell and Taste, Technische Universität Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Testicular cancer is the most frequent malignant disease in young males between 15 and 35 years. Platinum based chemotherapy regimen is the therapy of choice in advanced disease. This treatment has also adverse effects caused by the cytostatic active substances, such as olfactory dysfunctions.
View Article and Find Full Text PDF