27 results match your criteria: "Integrative Neuroscience and Cognition Center (INCC)[Affiliation]"
Commun Biol
July 2024
Sorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, Paris, 75013, France.
The neuroscience of consciousness aims to identify neural markers that distinguish brain dynamics in healthy individuals from those in unconscious conditions. Recent research has revealed that specific brain connectivity patterns correlate with conscious states and diminish with loss of consciousness. However, the contribution of these patterns to shaping conscious processing remains unclear.
View Article and Find Full Text PDFFront Neurosci
May 2024
Integrative Neuroscience and Cognition Center (INCC), CNRS, Université Paris Cité, Paris, France.
This short review examines recent advancements in neurotechnologies within the context of managing unilateral spatial neglect (USN), a common condition following stroke. Despite the success of brain-computer interfaces (BCIs) in restoring motor function, there is a notable absence of effective BCI devices for treating cerebral visual impairments, a prevalent consequence of brain lesions that significantly hinders rehabilitation. This review analyzes current non-invasive BCIs and technological solutions dedicated to cognitive rehabilitation, with a focus on visuo-attentional disorders.
View Article and Find Full Text PDFFront Psychol
January 2024
Integrative Neuroscience and Cognition Center (INCC-UMR 8002), Université Paris Cité-CNRS, Paris, France.
Introduction: The auditory system encodes the phonetic features of languages by processing spectro-temporal modulations in speech, which can be described at two time scales: relatively slow amplitude variations over time (AM, further distinguished into the slowest <8-16 Hz and faster components 16-500 Hz), and frequency modulations (FM, oscillating at higher rates about 600-10 kHz). While adults require only the slowest AM cues to identify and discriminate speech sounds, infants have been shown to also require faster AM cues (>8-16 Hz) for similar tasks.
Methods: Using an observer-based psychophysical method, this study measured the ability of typical-hearing 6-month-olds, 10-month-olds, and adults to detect a change in the vowel or consonant features of consonant-vowel syllables when temporal modulations are selectively degraded.
Antioxidants (Basel)
November 2023
Pôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent (PHUPEA), Centre Hospitalier Guillaume Regnier, 154 rue de Châtillon, 35000 Rennes, France.
The article presents a review of the relationships between melatonin and neurodevelopmental disorders. First, the antioxidant properties of melatonin and its physiological effects are considered to understand better the role of melatonin in typical and atypical neurodevelopment. Then, several neurodevelopmental disorders occurring during infancy, such as autism spectrum disorder or neurogenetic disorders associated with autism (including Smith-Magenis syndrome, Angelman syndrome, Rett's syndrome, Tuberous sclerosis, or Williams-Beuren syndrome) and neurodevelopmental disorders occurring later in adulthood like bipolar disorder and schizophrenia, are discussed with regard to impaired melatonin production and circadian rhythms, in particular, sleep-wake rhythms.
View Article and Find Full Text PDFFront Pediatr
June 2023
Université Paris Cité, CNRS, Integrative Neuroscience and Cognition Center (INCC), Paris, France.
Aim: To examine the effects of an early home-based 8-week crawling intervention performed by trained therapists on the motor and general development of very premature infants during the first year of life.
Methods: At term-equivalent age, immediately following discharge from the Neonatal Intensive Care Unit (NICU), we randomly allocated 44 premature infants born before 32 weeks' gestation without major brain damage to one of three conditions in our intervention study: crawling on a mini-skateboard, the Crawliskate (Crawli), prone positioning control (Mattress), or standard care (Control). The Crawli and Mattress groups received 5 min daily at-home training administered by trained therapists for 8 consecutive weeks upon discharge from the NICU.
Biomedicines
February 2023
Laboratory of Immunology, Pasteur Institute, 75015 Paris, France.
Many and diverse autoimmune abnormalities have been reported in children with autism. Natural autoantibodies (NAAbs) play important immunoregulatory roles in recognition of the immune self. The objective of this study was to examine the presence of NAAbs in the sera of children with autism and across severity subgroups of autistic behavioral impairments.
View Article and Find Full Text PDFEncephale
September 2022
Pôle hospitalo-universitaire de psychiatrie de l'enfant et de l'adolescent (PHUPEA), centre hospitalier Guillaume-Régnier, Université de Rennes 1, 35000 Rennes, France; Integrative Neuroscience and Cognition Center (INCC), CNRS UMR 8002, University of Paris Cité, Paris, France. Electronic address:
A multiphasic time model, integrating the past, present and future in close interrelations, is first presented and offers a contextual approach to the perceptions and responses of an individual according to his/her personal history and environment. The present and future prospects are in continuity with the past and its consequences and effects. The past, even when it is not or no longer expressed, influences the present and the future, and this over several generations.
View Article and Find Full Text PDFEncephale
September 2022
University Hospital Center for Child and Adolescent Psychiatry (PHUPEA), Guillaume-Régnier Hospital Center, University of Rennes 1, 35000 Rennes, France; Integrative Neuroscience and Cognition Center (INCC), CNRS UMR 8002, University of Paris Cité, Paris, France. Electronic address:
Aggressive behaviors could be considered as a dynamic of communication, in which aggression is a language to be understood, to be deciphered by two protagonists : the aggressor coping with a stressful and threatening situation and the aggressed individual coping with an aggressive acting out. The following questions are addressed: (a) What does aggression mean to the aggressor, what does it mean to the aggressed individual? (b) What does the aggressor want or try to express, and why does he or she use this mode of expression and action over another? (c) How does the aggressed individual react, and what is the impact of his or her response on the aggressor? This article reviews studies on the definition of aggression, its measurement, its developmental role and its associated risk factors in children and adolescents. First, aggression in children and adolescents with typical and atypical development is examined based on a developmental approach, clinical case studies in child and adolescent psychiatry, and an empirical study on aggression in autism.
View Article and Find Full Text PDFEncephale
September 2022
Pôle hospitalo-universitaire de psychiatrie de l'enfant et de l'adolescent (PHUPEA), centre hospitalier Guillaume-Régnier, Université de Rennes 1, 35000 Rennes, France; Integrative Neuroscience and Cognition Center (INCC), CNRS UMR 8002, University of Paris Cité, Paris, France. Electronic address:
The prevalence of school bullying (a deliberate, repeated act of verbal, physical or relational/social aggression occurring in a situation of inequality, including cyberbullying) is high in France (10 %) as well as in other countries like the United States (more than 40 % of school children have experienced harassment at some point in their school cursus). This frequency varies by country, source of observation, school, class, and age of children. Self-questionnaires where children have to self-identify as harassing or being harassed involve a clear bias of underevaluation (even for harassed children who can feel ashamed to report explicitly harassment).
View Article and Find Full Text PDFInfant Behav Dev
May 2022
Department of Experimental Clinical and Health Psychology, Ghent University, Belgium.
Language acquisition in the first year of life plays an important role in human development. Although recent research has increased our knowledge of early language development, the origins and developmental trajectories of language processing during infancy are still being debated. One important issue is whether the infant brain has already developed adult-like functional cortical specialization and lateralization for speech and language processing.
View Article and Find Full Text PDFExp Brain Res
January 2022
Institut des Systèmes Intelligents et de Robotique (ISIR), Sorbonne Université, Paris, France.
Information can be perceived from a multiplicity of spatial perspectives, which is central to effectively understanding and interacting with our environment and other people. Sensory impairments such as blindness are known to impact spatial representations and perspective-taking is often thought of as a visual process. However, disturbed functioning of other sensory systems (e.
View Article and Find Full Text PDFInt J Mol Sci
August 2021
Pôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent (PHUPEA), Centre Hospitalier Guillaume Régnier, University of Rennes 1, 35000 Rennes, France.
J Psychiatr Res
August 2021
Division of Neuroscience and Experimental Psychology, Faculty of Biological Medical & Health Sciences, University of Manchester, Oxford Road, M13 9PL, UK; Dept of Child and Adolescent Mental Health, Manchester University NHS Foundation Trust, Manchester, UK; Manchester Academic Health Sciences Centre, Manchester, M13 9PL, UK. Electronic address:
The impact of the Neurofibromatosis type 1 (NF1) on cognition have been subject to much clinical investigation, but environmental modifiers of disease expression have not yet been systematically investigated. The aim of this paper is to determine the role of demographic and environmental factors such as age, sex, socioeconomic status, parental NF1 status and neurological complications on the cognitive, behavioural and academic outcomes in NF1. Participants included 206 children aged 4-18 years seen within the Manchester clinical research NF1 service.
View Article and Find Full Text PDFBrain Res
September 2021
Centre National de la Recherche Scientifique (CNRS), Integrative Neuroscience and Cognition Center (INCC), Unité Mixte de Recherche, 8002 75006 Paris, France; Université de Paris, 75006 Paris, France; Fondation Ophtalmologique Rothschild, Paris, France. Electronic address:
Stimulus repetition can result in a reduction in neural responses (i.e., repetition suppression) in neuroimaging studies.
View Article and Find Full Text PDFTrends Cogn Sci
September 2021
Department of Developmental and Social Psychology (DPSS), Università di Padova, Padua, Italy; Integrative Neuroscience and Cognition Center (INCC), Centre National de la Recherche Scientifique (CNRS), Université de Paris, Paris, France.
We examine the beginning of the acquisition of the relative order of function and content words, a fundamental but cross-linguistically highly variable aspect of grammar. A review of the existing empirical literature shows that infants as young as 8 months of age can distinguish between functors and content words, and have a rudimentary knowledge of the order of these two universal lexical categories in their native language. Furthermore, human adults and non-human animals such as rodents process the same linguistic information differently from infants, emphasizing the developmental relevance of bootstrapping function/content word order from surface cues available in the input.
View Article and Find Full Text PDFCognition
August 2021
Integrative Neuroscience and Cognition Center (INCC UMR8002), Université de Paris & CNRS, Paris, France; University of Padua, Padua, Italy. Electronic address:
In the majority of languages, the functional distinction between functors and content words correlates with lower-level, perceptually observable properties. Functors are generally more frequent and prosodically more minimal than content words. Previous studies demonstrate that the frequency distribution and the different acoustic realization of frequent and infrequent words guide infants in discovering their native word order.
View Article and Find Full Text PDFInt J Mol Sci
February 2021
Inserm, CIC 1414 (Clinical Investigation Center), 35033 Rennes, France.
The role of melatonin has been extensively investigated in pathophysiological conditions, including autism spectrum disorder (ASD). Reduced melatonin secretion has been reported in ASD and led to many clinical trials using immediate-release and prolonged-release oral formulations of melatonin. However, melatonin's effects in ASD and the choice of formulation type require further study.
View Article and Find Full Text PDFFrom the earliest months of life, infants prefer listening to and learn better from infant-directed speech (IDS) than adult-directed speech (ADS). Yet, IDS differs within communities, across languages, and across cultures, both in form and in prevalence. This large-scale, multi-site study used the diversity of bilingual infant experiences to explore the impact of different types of linguistic experience on infants' IDS preference.
View Article and Find Full Text PDFCereb Cortex
March 2021
Jyväskylä Centre for Interdisciplinary Brain Research, Department of Psychology, University of Jyväskylä, 40014 Jyväskylä, Finland.
From the perspective of predictive coding, our brain embodies a hierarchical generative model to realize perception, which proactively predicts the statistical structure of sensory inputs. How are these predictive processes modified as we age? Recent research suggested that aging leads to decreased weighting of sensory inputs and increased reliance on predictions. Here we investigated whether this age-related shift from sensorium to predictions occurs at all levels of hierarchical message passing.
View Article and Find Full Text PDFBJPsych Open
August 2020
Pôle Hospitalo-Universitaire de Psychiatrie de l'Enfant et de l'Adolescent (PHUPEA), Centre Hospitalier Guillaume Régnier (CHGR) and Université de Rennes 1; and Integrative Neuroscience and Cognition Center (INCC), CNRS UMR 8002 and Université de Paris, France.
Background: Several studies suggest significant relationships between migration and autism spectrum disorder (ASD) but there are discrepant results. Given that no studies to date have included a pathological control group, the specificity of the results in ASD can be questioned.
Aims: To compare the migration experience (premigration, migratory trip, postmigration) in ASD and non-ASD pathological control groups, and study the relationships between migration and autism severity.
While phonological development is well-studied in infants, we know less about morphological development. Previous studies suggest that infants around one year of age can process words analytically (i.e.
View Article and Find Full Text PDFFront Psychiatry
March 2020
Hôpital de Ville Evrard, Unité de Recherche Clinique, Neuilly-sur-Marne, France.
Cerebellum plays a role in the regulation of cognitive processes. Cerebellar alterations could explain cognitive impairments in schizophrenia. We describe the case of a 50 years old patient with schizophrenia whom underwent cerebellar transcranial direct current stimulation (tDCS).
View Article and Find Full Text PDFCurr Biol
April 2020
Integrative Neuroscience and Cognition Center (INCC UMR8002), Université Paris Descartes, 45 rue des Saints-Pères, 75006 Paris, France; Integrative Neuroscience and Cognition Center (INCC UMR8002), CNRS, 45 rue des Saints-Pères, 75006 Paris, France. Electronic address:
The linguistic distinction between function words (functors) (e.g., the, he, that, on…), signaling grammatical structure, and content words (e.
View Article and Find Full Text PDFPLoS One
March 2020
Department of Psychology, University of British Columbia, Vancouver, British Columbia, Canada.
The input contains perceptually available cues, which might allow young infants to discover abstract properties of the target language. Thus, word frequency and prosodic prominence correlate systematically with basic word order in natural languages. Prelexical infants are sensitive to these frequency-based and prosodic cues, and use them to parse new input into phrases that follow the order characteristic of their native languages.
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