1 results match your criteria: "Instituto Universitario - Department of Obstetrics and Gynecology[Affiliation]"
Cost-effectiveness of cytogenetic evaluation of products of conception by chorionic villus sampling in recurrent miscarriage.
Prenat Diagn
March 2017
Centro de Educación Médica en Investigaciones Clínicas (CEMIC), Instituto Universitario - Department of Obstetrics and Gynecology, Genetic Unit, Galvan 4102, Buenos Aires, Buenos Aires 1425, Argentina.
Objective: To compare the cost-effectiveness of performing chorionic villus sampling (CVS) of products of conception (POC) in the evaluation of recurrent miscarriage versus standard evidence-based work-up (EBW) of the couple.
Material And Methods: A decision-analytic model was performed in couples with a third miscarriage. Three strategies were considered: (1) the standard EBW of all the patients, comprising parental karyotype, uterine cavity assessment and antiphospholipid antibodies; (2) performing a CVS of POC and a standard karyotype, and if euploid, follow with EBW; and (3) performing a CVS of POC and an arrayCGH and, if normal, follow with EBW.