2 results match your criteria: "Institute of Virology und Immunobiology[Affiliation]"
The Acid Ceramidase Is a SARS-CoV-2 Host Factor.
Cells
August 2022
Institute of Virology und Immunobiology, Julius-Maximilians-Universität Würzburg, Versbacher Str. 7, 97078 Würzburg, Germany.
SARS-CoV-2 variants such as the delta or omicron variants, with higher transmission rates, accelerated the global COVID-19 pandemic. Thus, novel therapeutic strategies need to be deployed. The inhibition of acid sphingomyelinase (ASM), interfering with viral entry by fluoxetine was reported.
View Article and Find Full Text PDFHIV patients treated with low-dose prednisolone exhibit lower immune activation than untreated patients.
BMC Infect Dis
January 2012
University of Wuerzburg, Institute of Virology und Immunobiology, 97078 Wuerzburg, Germany.
Background: HIV-associated general immune activation is a strong predictor for HIV disease progression, suggesting that chronic immune activation may drive HIV pathogenesis. Consequently, immunomodulating agents may decelerate HIV disease progression.
Methods: In an observational study, we determined immune activation in HIV patients receiving low-dose (5 mg/day) prednisolone with or without highly-active antiretroviral therapy (HAART) compared to patients without prednisolone treatment.