Ayush [Indian System of Medicines] Prophylaxis Against COVID-19: A Living Systematic Review and Meta-Analysis (Second Update).

Ayush (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy) system of medicine has been extensively used in India for the prevention and management of coronavirus disease 2019 (COVID-19). The present report is the second update of a living systematic review and meta-analysis and has been intended to assess the preventive potential and safety of Ayush drugs against COVID-19. A search of databases such as PubMed, the Cochrane central register of controlled trials, the World Health Organization (WHO) COVID-19 database, the clinical trial registry-India, the AYUSH research portal, and preprint repositories was performed till March 1, 2023.

A case-control study for exploring the association of Prakriti with Rheumatoid Arthritis.

Background: Deha-Prakriti (DP) is a unique contribution of Ayurveda, which distinguishes the population into three main groups viz., Vata, Pitta, and Kapha predominant individuals. Its assessment helps physicians to prescribe a suitable diet, daily regimen, and lifestyle that prevents non-communicable diseases.

Review of grey literature on Ayurveda wound healing formulations and procedures - A systematic review.

In the era of globalization and evidence-based medicines, a systematic documentation of information by compiling the studies carried out in different parts of India could be useful for the clinicians of Ayurveda and to the ailing community. In this review, an attempt has been made to compile all such clinical research works carried out on Vrana Ropana (wound healing). A grey literature of post graduate (PG) and Doctorate (PhD) researches on Vrana Ropana from various Ayurvedic institutes were collected in the form of soft or/and hard copy as per the availability.

Ayurvedic management of idiopathic small fibre neuropathy- A case report.

Small fibre neuropathy (SFN) is a subgroup of peripheral neuropathy which is characterized by a disorder of the thin myelinated A-δ and unmyelinated C-fibres. With a prevalence of 52.95 per 100,000 population per year, the reported etiology of SFN has remained unclear in 23-93% of investigated patients and hence termed idiopathic small fibre neuropathy (iSFN).

Evaluation of the anti-arthritic activity of Rhuflex-F - A proprietary Ayurvedic herbomineral formulation in albino rats.

Background: Rhuflex-F is a proprietary Ayurvedic herbo-mineral formulation clinically used to combat and relieve stiffness in joints and muscles, reduce edema, restore mobility, and also effective in relieving the symptoms of other autoimmune illnesses that lead to rheumatism.

Aims: The aim and objective of the research study is to evaluate the efficacy of Rhuflex-F against protein denaturation and Freund's adjuvant-induced arthritis in albino rats.

Materials And Methods: inhibition of protein denaturation activity was carried out using bovine serum albumin.

The intervention of epithelial-mesenchymal transition in homeostasis of human retinal pigment epithelial cells: a review.

The health and activity of photoreceptors and Bruch's membrane are promoted by the retinal pigment epithelium (RPE), which is essential for normal vision. Age-related macular degeneration (AMD), diabetic retinopathy (DR), and proliferative vitreoretinopathy (PVR) are examples of retinopathies that result in vision loss. Epithelial-mesenchymal transition (EMT) is a process in which epithelial cells transform into mesenchymal cells as a result of a faulty microenvironment, and it is associated with the oculopathies stated above.

AYUSH (Indian System of Medicines) Therapeutics for COVID-19: A Living Systematic Review and Meta-Analysis (First Update).

In India, alternative and complementary therapies (Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homeopathy [AYUSH] medicines) are extensively utilized in COVID-19 management, and some were investigated clinically. This study assessed the effectiveness of AYUSH therapeutic on COVID-19 through a living systematic review and meta-analysis approach. Databases like PubMed; the Cochrane central register of controlled trials; WHO COVID-19 database; the central trial registry-India; Digital Helpline for Ayurveda Research Articles and AYUSH research portal, and preprint repositories were searched till August 1, 2021.

Impact of AYUSH 64 as an adjunctive to standard of care in mild COVID 19 - An open-label randomized controlled pilot study.

Background: Ayurveda herbal formulation AYUSH-64, proven to treat malaria and influenza-like illness in india was repurposed for COVID-19 patients considering preliminary evidances, however, scientific data was not available.

Aim: To evaluate the preliminary efficacy and safety of AYUSH 64 as an add-on to standard of care in mild COVID19 patients.

Materials And Methods: A single centre, randomized, open-labeled, controlled, pilot study were conducted on mild COVID 19 confirmed patients.

, an Ayurvedic Pharmaceutical Method and a Versatile Drug Delivery Platform to Prepare Potentiated Micro-Nano-Sized Drugs: Core Concept and Its Current Relevance.

Scholars of ancient Ayurveda (Indian system of medicine) were extremely reasonable and had strong scientific rationality in fundamental concepts, which are also applied to drug manufacture and therapy. is a unique traditional method of transformation of raw material/substances into the drug by levigation or wet grinding of powdered drugs with juice/decoction/solution of plant, animal, or mineral origin. This method adds the unique capability of affecting the physicochemical and biological properties of a drug, making the drug quicker, augmented, and persistent action with minimal dose.

(Ayurveda medication) improves the perceived immunity in individuals at risk of SARS-CoV-2: A Multicentred, controlled, before-and-after study.

During the COVID-19 pandemic in India, Ayurvedic medication ( GG) was prescribed by Ayurveda physicians for prevention and management. This study aimed to evaluate the prophylactic effect of GG in individuals with moderate to very high risk of SARS-CoV-2. A multicenter, controlled, quasi-experimental, before-and-after study was conducted on individuals at moderate to very high risk of SARS-COV-2 exposure.

Knowledge, attitude and practice towards pharmacovigilance among ayurveda physicians and teachers of Gujarat State: A cross sectional study.

Aim: The aim of this study was to assess the knowledge, attitude, and practice towards pharmacovigilance for Ayurveda among the teachers and practitioners working in Ayurveda colleges of Gujarat State.

Materials And Methods: A survey questionnaire with 29 questions covering points like participants' knowledge, attitude and practice towards pharmacovigilance, adverse drug reaction reporting, and misleading advertisements related Ayurveda drugs was developed in Google form format. The study was carried out during December 2020 and January 2021.

Impact of AYUSH interventions on COVID-19: a protocol for a living systematic review and meta-analysis.

The coronavirus disease 2019 (COVID-19) pandemic has created a great burden on governments and the medical fraternity globally. Many clinical studies from the Indian system of Traditional Medicines [Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homoeopathy (AYUSH)] have been carried out to find appropriate solutions. Through a living systematic review and meta-analysis, this study aims to determine the effectiveness of the Traditional System of Indian Medicine (AYUSH system) in lowering the incidence, duration, and severity of COVID-19.

Evaluation of acute toxicity and antiulcer activity of Pepgard tablet: An Ayurvedic formulation.

Background: In traditional Indian medicine, several plants have been used to treat gastrointestinal disorders, including gastric ulcers. Pepgard tablet is an Ayurvedic compound formulation widely used in clinical practice as an antacid for treating nonulcer dyspepsia, gastroesophageal reflux, and drug-induced gastritis.

Aim: Evaluation of acute toxicity of Pepgard tablet and antiulcer activity against gastric ulcer induced by aspirin plus pyloric ligation in albino rats.

with (honey) along with adjuvant therapy in the management of trigger finger- A single case report.

Trigger finger (TF) mechanical ailment results from a stenotic A1 pulley that has lost its gliding surface, producing friction and nodular change in the tendon. This results in pain and tenderness at the site of the A1 pulley which further progresses into catching and then locking of the finger. A definite cure of TF in the current mainstream is the surgical release of the A1 pulley.

Adaptogenic and immunomodulatory activity of Virgozest - An ayurvedic proprietary formulation.

Introduction: (rejuvenator) or adaptogenic drugs have been proved to produce the complete potential to prevent diseases and degenerative changes that leads to diseases and promote longevity by providing strength and immunity. Virgozest is a poly-herbal formulation claimed to serve as adaptogenic, and immunomodulatory, as a health tonic, enriched with dry fruits, and ingredients containing natural supplements of Vitamin E and proteins.

Aim: To evaluate the adaptogenic activity and humoral immune activity of virgozest in Wistar albino rats.

Efficacy of & in the managment of w.s.r. iron deficiency anemia in children- An open labelled comparative clinical trial.

Background: Anemia is a public health problem worldwide, and its prevalence in India is higher than any other south asian countries. Iron deficiency anemia (IDA) is having larger share out of all types of anaemia's. Symptomatology of IDA resembles with dominant variety of .

Central nervous system depressant activity of ( DC.) rhizome.

Background: Sleep disorders have a comparatively high prevalence worldwide and create a burden on the health system. Pharmacological agents used for insomnia are associated with considerable side effects. Therefore, searching for safe and effective agents from plant-based natural sources is a worthy effort.