1 results match your criteria: "Institute of Special Wild Economic Animal and Plants[Affiliation]"
Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2/TLR4 Signaling Pathway.
Stem Cells Int
March 2020
Institute of Special Wild Economic Animal and Plants, Chinese Academy of Agricultural Sciences, Changchun, China.
Article Synopsis
- Postoperative cognitive dysfunction (POCD) is a serious issue following cardiopulmonary bypass (CPB), leading to problems like memory loss and trouble concentrating.* -
- Mesenchymal stem cells (MSCs) can be beneficial through their secretions, and this study focused on exosomes from antler MSCs (AMSCs) in the context of POCD in rats.* -
- The research found that AMSC-derived exosomes mitigated brain and neurological damage in CPB rats, potentially by inhibiting the TLR2/TLR4 signaling pathway, although this effect was reduced when a TLR2/TLR4 agonist was introduced.*