317 results match your criteria: "Institute of Science and Technology in Medicine[Affiliation]"

Loss of Consciousness in Judo: Not Always a Concussion.

Clin J Sport Med

October 2024

Department of Trauma and Orthopaedic Surgery, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy; and.

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Purpose: The use of a fixed theoretical-proportional-factor (TPF) is one of the indirect highest-oxygen-consumptions (HOC) assessment methods, but it may not accurately reflect the physiological differences across various sports (cycling-triathlon-running-football-multisport). The aim of this study is to evaluate the variability of TPF across different sports, proposing a series of sport-specific new TPF values for more accurate HOC estimation.

Methods: A sample of 340 adults (26.

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Article Synopsis
  • Contractures, which are common after a stroke and can limit joint movement and cause additional problems, may be managed through assistive technologies to facilitate recovery and rehabilitation.
  • The study aimed to evaluate the effects of various assistive devices on managing contractures in stroke patients by reviewing randomized controlled trials.
  • Seven studies were included in the review, with five undergoing meta-analysis, focusing primarily on the effectiveness of assistive technology compared to standard therapy, showing beneficial outcomes for joint range of motion.
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Shoulder balloon spacer for massive irreparable rotator cuff tears results in significant improvements.

Knee Surg Sports Traumatol Arthrosc

August 2024

Barts and the London School of Medicine and Dentistry, Centre for Sports and Exercise Medicine, Mile End Hospital, Queen Mary University of London, London, England.

Purpose: The aim of the present study was to assess the effectiveness of balloon implantation in patients with irreparable supraspinatus tears alone or in combination with other rotator cuff (RC) tendon tears and the effect of several covariables, such as age, gender, status of the long head biceps, with or without tendon repair and regardless the number of tendon involved.

Methods: Patients enrolled from 'San Carlo' Hospital of Potenza (Italy, IT), from January 2012 to September 2014, underwent arthroscopic implantation of shoulder balloon by a single surgeon, and followed for 3 years. The American Shoulder and Elbow Surgeons (ASES) and Constant score (CS) were administered pre-, post-operatively at 12 months, and then annually.

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Background: Kickboxing is a popular striking combat sport, and K-1 is a type of kickboxing. Direct head blows can cause significant long-term injury and affect brain wave activity.

Objectives: We aim to compare the changes in brain wave activities of fighters during a K-1 kickboxing contest to those in a control group, who were striking a punching bag and were not hit by another K-1 athlete.

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Heel pain in young athletes - not always Sever's Disease: A Narrative Review.

Foot (Edinb)

September 2024

Department of Physical Activity and Health, Paavo Nurmi Centre, University of Turku, Turku, Finland; FinnOrthopaedics / Hospital Pihlajalinna, Turku, Finland; Ripoll y De Prado, FIFA Medical Centre of Excellence, Madrid, Spain. Electronic address:

Heel pain is a prevalent issue in young athletes, often arising from overuse and increased sporting demands. While Sever's Disease is the predominant cause, various other entities, including stress-related injuries and pathologies like tumors and bone lesions, contribute to this condition. The complex hind foot anatomy, encompassing ossicles, physis, and soft tissues, may lead to heel pain.

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Purpose: To evaluate the mid-term clinical outcomes for the non-surgical and surgical management of acute proximal hamstring avulsions.

Methods: Sixty physically active individuals were offered surgical or non-surgical management for their proximal hamstring avulsion injuries. Distal retraction was defined as greater than 2 cm.

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Long head of biceps tendon augmentation for massive rotator cuff tears improves clinical results regardless of the number of tendons involved.

Knee Surg Sports Traumatol Arthrosc

July 2024

Barts and the London School of Medicine and Dentistry, Centre for Sports and Exercise Medicine, Mile End Hospital, Queen Mary University of London, London, UK.

Article Synopsis
  • * A total of 55 patients were included, and significant improvements were noted in shoulder pain and function scores from preoperative assessments to follow-ups at 3, 6, and 12 months post-surgery.
  • * No adverse effects occurred during the study, indicating that LHBT augmentation may be a safe and effective strategy for managing MRCTs in motivated patients.
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Article Synopsis
  • * Data was collected from patients before and after surgery, with a follow-up period of at least three months and an average of six months, using various statistical methods.
  • * The Danish EFAS Score demonstrated high internal consistency (Cronbach's Alpha 0.88) and significant patient improvement post-treatment, indicating its successful validation for diverse foot and ankle issues.
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Complete endothelialisation of coronary stents is an important determinant of future thrombotic complications following coronary stenting. Stent surface texture is an important factor that influences endothelial cell growth. With the emergence of second and third generation coronary stents, is limited comparative data describing endothelial cell growth in contemporary stent platforms, and limited data available on approaches used to rapidly modify the surfaces of commercial coronary stents to improve endothelialisation.

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Data-driven models for the prediction of coronary atherosclerotic plaque progression/regression.

Sci Rep

January 2024

National Laboratory for Scientific Computing (LNCC-MCTI), Petrópolis, RJ, Brazil.

Coronary artery disease is defined by the existence of atherosclerotic plaque on the arterial wall, which can cause blood flow impairment, or plaque rupture, and ultimately lead to myocardial ischemia. Intravascular ultrasound (IVUS) imaging can provide a detailed characterization of lumen and vessel features, and so plaque burden, in coronary vessels. Prediction of the regions in a vascular segment where plaque burden can either increase (progression) or decrease (regression) following a certain therapy, has remained an elusive major milestone in cardiology.

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Background: Recent clinical data indicate a different performance of biodegradable polymer (BP)-drug eluting stent (DES) compared to durable polymer (DP)-DES. Whether this can be explained by a beneficial impact of BP-DES stent design on the local hemodynamic forces distribution remains unclear.

Objectives: To compare endothelial shear stress (ESS) distribution after implantation of ultrathin (us) BP-DES and DP-DES and examine the association between ESS and neointimal thickness (NIT) distribution in the two devices at 9 months follow up.

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Aims: This study aims to report the medium term outcomes of circumferential periosteal release of the distal femur and distal tibia in treating paediatric leg length discrepancy (LLD).

Materials And Methods: A retrospective case series was performed on all patients undergoing circumferential periosteal release of the distal femur and/or tibia between 2006 and 2019. Data collected included demographics, surgical indications, post-operative leg lengths, and complications.

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In recent years, several works have addressed the problem of modeling blood flow phenomena in veins, as a response to increasing interest in modeling pathological conditions occurring in the venous network and their connection with the rest of the circulatory system. In this context, one-dimensional models have proven to be extremely efficient in delivering predictions in agreement with observations. Pursuing the increase of anatomical accuracy and its connection to physiological principles in haemodynamics simulations, the main aim of this work is to describe a novel closed-loop Anatomically-Detailed Arterial-Venous Network (ADAVN) model.

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The role of the mechanical environment in defining tissue function, development and growth has been shown to be fundamental. Assessment of the changes in stiffness of tissue matrices at multiple scales has relied mostly on invasive and often specialist equipment such as AFM or mechanical testing devices poorly suited to the cell culture workflow.In this paper, we have developed a unbiased passive optical coherence elastography method, exploiting ambient vibrations in the sample that enables real-time noninvasive quantitative profiling of cells and tissues.

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Background: The Score Committee of the European Foot and Ankle Society (EFAS) developed, validated, and published the EFAS Score in 11 languages (Dutch, English, German, Finnish, French, Italian, Polish, Portuguese, Persian, Swedish, Turkish). From other languages under validation, the Spanish and Estonian versions completed data acquisition and underwent further validation.

Methods: The EFAS Score was developed and validated in three stages: 1) item (question) identification (completed during the initial validation study), 2) item reduction and scale exploration (completed during the initial validation study), 3) confirmatory analyses and responsiveness of the Spanish and Estonian versions (completed during the initial validation study in seven other languages).

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Introduction: Rotator cuff tears (RCT) are a common cause of shoulder pain and disability, with massive RCT accounting for 10-40% of all rotator cuff tears.

Sources Of Data: A systematic search of PubMed and Scopus electronic databases was performed up to August 2022, and a total of 17 scientific articles were included in the present PRISMA compliant systematic review.

Areas Of Agreement: Understanding the geometric patterns in RCT is essential to achieve appropriate repositioning of the injured tendons in their anatomic location.

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Therapeutic ultrasound related pain threshold in elite track & field athletes with tibial bone stress injuries.

Surgeon

August 2023

Centre for Sports and Exercise Medicine, Queen Mary, University of London, London, UK; First Department of Orthopaedic Surgery, Aristotle University of Thessaloniki, Greece; Department of Orthopaedics, School of Medicine, Surgery and Dentistry, Salerno, Italy; Institute of Science and Technology in Medicine, Keele University School of Medicine, Stoke on Trent, United Kingdom. Electronic address:

Objective: Tibial stress injuries are challenging in terms of early diagnosis, management strategy, and safe return-to-play. In the present study, pain production associated with the application of therapeutic ultrasound (TUS) was used as a primary diagnostic tool to assess tibial bone stress injuries, and the sensitivity of this procedure was compared with Magnetic Resonance Imaging (MRI).

Subject And Methods: The study was designed as a retrospective analysis of prospectively collected data on tibial bone stress injuries in elite Track and field athletes attending the National Track and Field Athletics Centre in Thessaloniki, Greece, in the period 1995-2007.

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A coaxial nanofibrous scaffold of poly (ε-caprolactone) and gelatin/cellulose acetate encapsulating anti-inflammatory and antibacterial drugs was co-electrospun for skin tissue regeneration. Indomethacin and ciprofloxacin as model drugs were added to the core and the shell solutions, respectively. The effect of the drugs’ presence and crosslinking on the scaffold properties was investigated.

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Background: The Score Committee of the European Foot and Ankle Society (EFAS) developed, validated, and published the EFAS Score in ten languages (English, German, French, Italian, Polish, Dutch, Swedish, Finnish, Turkish, Portuguese). From other languages under validation, the Portuguese version completed data acquisition and underwent further validation.

Methods: The Portuguese version of the EFAS Score was developed and validated in three stages: 1) item (question) identification (completed during initial validation study), 2) item reduction and scale exploration (completed during initial validation study), 3) confirmatory analyses and responsiveness of Portuguese version (completed during initial validation study in nine other languages).

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Scaling laws and the left main coronary artery bifurcation. A combination of geometric and simulation analyses.

Med Eng Phys

January 2022

Hospital Israelita Albert Einstein. São Paulo, Brazil; Department of Interventional Cardiology, Heart Institute (InCor) and the University of São Paulo Medical School, 05403-904, São Paulo, Brazil; National Institute of Science and Technology in Medicine Assisted by Scientific Computing, Petrópolis, Brazil. Electronic address:

The geometry of coronary arteries is believed to play the role as an atherosclerotic risk factor on its own. The full characterization of the normal coronary network has been reported in the literature. Reports on the integration of geometry and functional data for normal coronary vessels started to proliferate more recently.

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Background: The shoulder joint is the most commonly injured joint in CrossFit practitioners, because of the high intensity and loads associated with this sport. Despite the large number of clinical cases, there is a shortage of studies that investigate influence of biomechanical aspects of upper limbs' injuries on CrossFit practitioners. This study hypothesized that there would be a difference in function, strength, and muscle activation between Crossfit practitioners with and without shoulder pain.

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Feasibility of coronary blood flow simulations using mid-fidelity numeric and geometric models.

Biomech Model Mechanobiol

February 2022

National Laboratory for Scientific Computing, LNCC/MCTI, Av. Getúlio Vargas, 333, Petrópolis, RJ, 25651-075, Brazil.

The fractional flow reserve index (FFR) is currently used as a gold standard to quantify coronary stenosis's functional relevance. Due to its highly invasive nature, the development of noninvasive surrogates based on simulations has drawn much attention in recent years, emphasizing efficient strategies that enable translational research. The focus of this work is twofold.

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Parallel generation of extensive vascular networks with application to an archetypal human kidney model.

R Soc Open Sci

December 2021

National Laboratory for Scientific Computing, LNCC/MCTI, Petrópolis, Brazil.

Given the relevance of the inextricable coupling between microcirculation and physiology, and the relation to organ function and disease progression, the construction of synthetic vascular networks for mathematical modelling and computer simulation is becoming an increasingly broad field of research. Building vascular networks that mimic morphometry is feasible through algorithms such as constrained constructive optimization (CCO) and variations. Nevertheless, these methods are limited by the maximum number of vessels to be generated due to the whole network update required at each vessel addition.

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Cartilage is a tension- and load-bearing tissue and has a limited capacity for intrinsic self-healing. While microfracture and arthroplasty are the conventional methods for cartilage repair, these methods are unable to completely heal the damaged tissue. The need to overcome the restrictions of these therapies for cartilage regeneration has expanded the field of cartilage tissue engineering (CTE), in which novel engineering and biological approaches are introduced to accelerate the development of new biomimetic cartilage to replace the injured tissue.

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