Triatomine (Hemiptera: Reduviidae) populations and Trypanosoma cruzi genotyping in peridomestic and sylvatic environments in the semiarid region of Sergipe, Northeastern, Brazil.

We assessed the diversity of triatomines, the rates of natural infection, and the discrete typing units (DTUs) of Trypanosoma cruzi isolated from them in two municipalities in the state of Sergipe, Brazil. Active searches for triatomines were conducted in the peridomicily and wild enviroments of 10 villages within the two municipalities. Triatomines were taxonomically identified and their feces were extracted using the abdominal compression method.

Regulatory insights into nanomedicine and gene vaccine innovation: Safety assessment, challenges, and regulatory perspectives.

This analysis explores the principal regulatory concerns linked to nanomedicines and gene vaccines, including the complexities involved and the perspectives on how to navigate them. In the realm of nanomedicines, ensuring the safety of nanomaterials is paramount due to their unique characteristics and potential interactions with biological systems. Regulatory bodies are actively formulating guidelines and standards to assess the safety and risks associated with nanomedicine products, emphasizing the need for standardized characterization techniques to accurately gauge their safety and effectiveness.

Formulation and Development of Novel Sulfasalazine Bilayer Tablets for The Treatment of Arthritis Associated With IBD: In-vitro and In-vivo Investigations.

Sulfasalazine needs frequent daily dosing and the administration of numerous tablets per day pose challenges to patient compliance, contributing to increased adverse effects and difficulties in disease control. These inconveniences result in less effective treatment for arthritis associated with inflammatory bowel disease i.e.

A rare case of mucoepidermoid carcinoma ex-pleomorphic adenoma of the hard palate.

Carcinoma Ex-Pleomorphic Adenoma (CExPA) is a salivary gland carcinoma derived from a primary or recurrent benign pleomorphic adenoma (PA) extremely rare in minor salivary glands. In this paper, we report the case of a male afrodescendant patient, 37 years old, presenting a palatal irregular nodular lesion with approximately 3.5 cm diameter.

Widening Blockchain Technology toward Access Control for Service Provisioning in Cellular Networks.

The attention on blockchain technology (BCT) to create new forms of relational reliance has seen an explosion of new applications and initiatives, to assure decentralized security and trust. Its potential as a game-changing technology relates to how data gets distributed and replicated over several organizations and countries. This paper provides an introduction to BCT, as well as a review of its technological aspects.

Extraction of hops pelletized (Humulus lupulus) with subcritical CO and hydrodistillation: Chemical composition identification, kinetic model, and evaluation of antioxidant and antimicrobial activity.

Hop essential oil and hop extract using carbon dioxide (CO) are products with high added value because they have bioactive and sensory properties. In this context, the objective of this study was to obtain and characterize essential oil and extracts from pelleted hops of El Dorado, Polaris, Hallertau Blanc and Callista varieties using hydrodistillation and subcritical CO extraction methods. Extraction yield ranged from 0.

Africanized Bee Venom ( Linnaeus): Neuroprotective Effects in a Parkinson's Disease Mouse Model Induced by 6-hydroxydopamine.

This study evaluated the neuroprotective effects of the Africanized bee venom (BV) and its mechanisms of action after 6-hydroxydopamine-(6-OHDA)-induced lesion in a mice model. Prior to BV treatment, mice received intrastriatal microinjections of 6-OHDA (no induced dopaminergic neuronal death) or ascorbate saline (as a control). BV was administered subcutaneously at different dosages (0.

Applications of cognitive internet of medical things in modern healthcare.

The sudden outbreak of the novel coronavirus disease in 2019, known as COVID-19 has impacted the entire globe and has forced governments of various countries to a partial or full lockdown in the fear of the rapid spread of this disease. The major lesson learned from this pandemic is that there is a need to implement a robust system by using non-pharmaceutical interventions for the prevention and control of new contagious viruses. This goal can be achieved using the platform of the Internet of Things (IoT) because of its seamless connectivity and ubiquitous sensing ability.

Mathematical modelling of bio-inspired frog leap optimization algorithm for transmission expansion planning.

Bio-inspired computing has progressed so far to deal with real-time multi-objective optimization problems. The Transmission expansion planning of the modern electricity grid requires finding the best and optimal routes for electricity transmission from the generation point to the endpoint while satisfying all the power and load constraints. Further, the transmission expansion cost allocation becomes a critical and pragmatic issue in the deregulated electricity industry.

Surgical declarative knowledge learning: concept and acceptability study.

Improving surgical training by means of technology assistance is an important challenge that aims to directly impact surgical quality. Surgical training includes the acquisition of two categories of knowledge: declarative knowledge (i.e.

Oral basaloid squamous cell carcinoma: A case report with emphasis on histopathological diagnosis criteria.

Basaloid squamous-cell carcinoma (BSCC) is an uncommon variant of squamous cell carcinoma (SCC) consisting of atypical squamous and basaloid cells. It is an aggressive lesion that most commonly affects the oropharynx, being rare in intraoral sites. In this paper, we report the case of a male patient, 42 years old, smoker and chronic drinker, presenting a vegetating and ulcerated leukoerythroplastic lesion, asymptomatic, with five months of evolution, located on the floor of the mouth.

Studies related to the chemical composition, biological activities and toxicity of methanolic extracts of noni () fruits and leaves.

is a plant that grows in Brazilian northeast and presented a wide range of therapeutic, industrial and technological applications. Based on this, the aim of this work was to study the chemical composition, main biological activities and potential toxicity of its extracts, aiming their industrial application. Important compounds were identified in the methanolic extracts obtained by ultrasonic and Soxhlet extractions from leaves and fruits.

Chemical Profiling and Evaluation of Antioxidant and Anticancer Potential of Tuber Crop Amorphophallus commutatus var. wayanadensis.

Cancer and cancer-related diseases are a global health concern in the present scenario. Functional food and nutraceuticals are considered as a boon towards cancer management. Amorphophallus commutatus var.

A semantic database for integrated management of image and dosimetric data in low radiation dose research in medical imaging.

Medical ionizing radiation procedures and especially medical imaging are a non negligible source of exposure to patients. Whereas the biological effects of high absorbed doses are relatively well known, the effects of low absorbed doses are still debated. This work presents the development of a computer platform called Image and Radiation Dose BioBank (IRDBB) to manage research data produced in the context of the MEDIRAD project, a European project focusing on research on low doses in the context of medical procedures.

Characteristics of follicular dynamics and reproductive hormone profiles during oestrous cycles of jennies over an entire year.

Although donkeys have been domesticated for over 6,000 years, limited information is available concerning their reproductive physiology, especially under intensive rearing conditions. The aims of this experiment were to study follicular dynamics and reproductive hormone variation in jennies during the inter-ovulatory interval in different seasons. A total of 12 continuous cycles of six Dezhou Black (DB) donkey jennies were examined in four different seasons.

Development and Characterization of Biointeractive Gelatin Wound Dressing Based on Extract of Linn.

Linn (pomegranate) extracts have been proposed for wound healing due to their antimicrobial, antioxidant, and anti-inflammatory properties. In this work, we designed biointeractive membranes that contain standard extracts of for the purpose of wound healing. The used standard extract contained 32.

Formulation development, and evaluation of chitosan engineered nanoparticles for ocular delivery of insulin.

Insulin-dependent diabetic patients have to count on the administration of painful and discomforting insulin injections. However, inadequate insulin absorption and the risk of insulin level escalation in the blood are some disadvantages associated with insulin therapy. Thus, the current study intends to formulate insulin-loaded chitosan nanoparticles for refining the systemic absorption of insulin the ocular route.

Studies on physiochemical modifications on biologically important hydroxyapatite materials and their characterization for medical applications.

Crystalline Hydroxyapatite (Ca10 (PO)(OH)) non linear optical crystal plays a major role in biomedical applications. Crystalline Hydroxyapatite was synthesized using natural human bone sample by thermal methods. This Hydroxyapatite was characterized by Fourier Transform infra-red spectroscopy (FTIR), scanning electron microscope, UV-Vis spectroscopy, X-ray diffraction and conductivity studies.

Occupational lower back pain among bus conductors of Udupi district, Karnataka.

Although studies have reported lower back pain (LBP) in professional drivers, the conductors travelling in the same bus who share the same working environment are often neglected. Thus, the present study was undertaken to assess the prevalence of LBP and the factors associated with it. The study included 237 bus conductors from government bus depots.

A multicentric IT platform for storage and sharing of imaging-based radiation dosimetric data.

Purpose: The MEDIRAD project is about the effects of low radiation dose in the context of medical procedures. The goal of the work is to develop an informatics service that will provide the researchers of the MEDIRAD project with a platform to share acquired images, along with the associated dosimetric data pertaining to the radiation resulting from the procedure.

Methods: The authors designed a system architecture to manage image data and dosimetric data in an integrated way.