Time-frequency analysis of spike-wave discharges using a modified wavelet transform.

The continuous Morlet wavelet transform was used for the analysis of the time-frequency pattern of spike-wave discharges (SWD) as can be recorded in a genetic animal model of absence epilepsy (rats of the WAG/Rij strain). We developed a new wavelet transform that allows to obtain the time-frequency dynamics of the dominating rhythm during the discharges. SWD were analyzed pre- and post-administration of certain drugs.

Computer simulation of the heart magnetic field dynamics.

A personal-computer based model, which enables the investigation of the correlation between the temporal dynamics of the magnetic field distribution and electrophysiological processes during ventricular depolarisation, has been tested. The activation sequence following a stimulus to the atrioventricular node or directly to the ventricular myocardium can be simulated in isotropic conditions and visualised in a three-dimensional presentation. The corresponding behaviour of the distribution of the normal component of the magnetic field is calculated using a simple algorithm.