New findings and symptomatic treatment for neurolathyrism, a motor neuron disease occurring in north west Bangladesh.

Neurolathyrism is a form of spastic paraparesis caused by the neuroexcitatory amino acid 3-N-oxalyl-L-2,3-diaminopropanoic acid (beta-ODAP) present in the seeds and foliage of Lathyrus sativus. The disease is irreversible and usually nonprogressive. Tolperisone HCl, a centrally acting muscle relaxant, has been shown to reduce significantly the spasticity in neurolathyrism patients.

Psychiatric morbidity in cancer patients.

One hundred and two patients of cancer were studied by two stage screening methods to detect the psychiatric morbidity in these patients. The General Health Questionnaire (60 item version) was used to detect the psychiatric morbidity. The psychiatric diagnosis was made according to DSM-IIIR criteria.

The bimodal mortality pattern of acute renal failure in children.

A total of 1784 children suffering from acute nonobstructive anuric renal failure requiring dialysis were studied in the Pediatrics Nephrology unit of Institute of Postgraduate Medicine and Research, Dhaka, Bangladesh, for the 10-year period 1981-1990. The patients were divided into two groups: Group I, the majority of the children (94.5%), presented with acute renal failure without evidence of hemolysis and were labeled as acute ischemic renal failure (AIRF), and the remaining 5.

Outcome of acute renal failure in adults in a teaching hospital in Bangladesh.

One hundred and twenty patients with a mean age of 38 years (range 12-85 years; M 91, F 37) were studied over a period of 5 years in a teaching hospital in Dhaka. Sixty-two patients presented with probable anuria with 1-4 days' duration, 63 patients presented with oliguria, and 3 were nonoliguric. The causes of acute renal failure were medical (94), surgical (22), obstetrical (13).

Rhesus genotype frequency in Bangladeshi population.

The prevalence of Rhesus genotypes in Bangladesh has been studied and several important findings were observed. This being the initial report, includes a population of 1600 only. By using five Rh antisera (Anti-C, Anti-D, Anti-E, Anti-c and Anti-e) a genotype can be deduced since anti-d is not available.

Factors influencing development of bulbar deformity in duodenal ulcer disease.

Sixty subjects were carefully interrogated and repeatedly endoscoped with a view to studying the effect of sucralfate on healing and recurrence of duodenal ulcer disease. Degree of bulbar deformity was noted during each endoscopy. During the trial it appeared that deformity progressed more rapidly in late onset subjects (onset at or above 30 years of age).

Duodenal ulcer dyspepsia in the first degree relatives of subjects with duodenal ulcer disease.

In a population survey, the point prevalence of duodenal ulcer disease (DUD) was found to be 11.98 percent which is the highest prevalence rate so far reported in the literature. The prevalence of duodenal ulcer dyspepsia in the first degree relatives of groups of subjects with proven duodenal ulcer, non ulcer dyspepsia (NUD) (duodenal ulcer dyspepsia but without evidence of ulcer at endoscopy) and normal healthy control (HC), all matched by age and sex and all from the population with the high prevalence of duodenal ulcer disease, were studied.