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Acta Physiol Hung
April 2005
Institute of Physiology of the Ernst-Moritz-Arndt-University of Greifswald, Greifswald, Germany.
Objective: To compare the cardiorespiratory responses underlying the beneficial effects of hyperoxia during blood loss between normotensive (WKY) and hypertensive (SHR) rats.
Methods: Experiments were carried out in anesthetized animals with both carotid bifurcations either innervated or denervated. The effects of breathing 60% O2 in N2 were studied either in combination with non-hypotensive hemorrhage or during hemorrhagic hypotension.