344 results match your criteria: "Institute of Pesticide and Environmental Toxicology[Affiliation]"

The jasmonic acid-amino acid conjugates JA-Val and JA-Leu are involved in rice resistance to herbivores.

Plant Cell Environ

January 2022

State Key Laboratory of Rice Biology, Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Institute of Insect Sciences, Zhejiang University, Hangzhou, China.

The phytohormone jasmonic acid (JA) plays a core role in plant defence against herbivores. When attacked by herbivores, JA and its bioactive derivatives are accumulated at the damage site, and subsequently perceived by the jasmonate co-receptors COI1 and JAZ proteins. The (+)-7-iso-jasmonoyl-L-isoleucine (JA-Ile) is known to be the main active JA derivative controlling vascular plant responses to herbivores as well as other JA-regulated processes.

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Estrogen receptor: A potential linker of estrogenic and dopaminergic pathways in zebrafish larvae following deltamethrin exposure.

Sci Total Environ

January 2022

Institute of Pesticide and Environmental Toxicology, Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Zhejiang University, Hangzhou 310058, PR China.

Deltamethrin (DM), a type II pyrethroid insecticide, is widely used to control agricultural pests. However, its excessive use exerts a detrimental effect on the ecological environment and human health, indicating the need to study its potential risks in detail. In the present study, zebrafish embryos were exposed to varying concentrations of DM (0.

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Uptake and translocation of triadimefon by wheat (Triticum aestivum L.) grown in hydroponics and soil conditions.

J Hazard Mater

February 2022

Institute of Pesticide and Environmental Toxicology, the Key Laboratory of Molecular Biology of Crop Pathogens and Insects, College of Agricultural and Biotechnology, Zhejiang University, Hangzhou 310058, China. Electronic address:

Residual pesticides in soil may be taken in by plants and thus have a risk for plant growth and food safety. In this study, uptake of triadimefon and its subsequent translocation and accumulation were investigated with wheat as model plants. The results from hydroponics indicated that triadimefon was absorbed by wheat roots mainly through apoplastic pathway and predominantly distributed into the water soluble fractions (66.

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Hyperspectral imaging with shallow convolutional neural networks (SCNN) predicts the early herbicide stress in wheat cultivars.

J Hazard Mater

January 2022

College of Biosystems Engineering and Food Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, China. Electronic address:

The toxicity impacts of herbicides on crop, animals, and human are big problems global wide. The rapid and non-invasive ways for assessing herbicide-responsible effects on crop growth regarding types and levels still remain unexplored. In this study, visible/near infrared hyperspectral imaging (Vis/NIR HSI) coupled with SCNN was used to reveal the different characteristics in the spectral reflectance of 2 varieties of wheat seedling leaves that were subjected to 4 stress levels of 3 herbicide types during 4 stress durations and make early herbicide stress prediction.

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Sodium channel activation underlies transfluthrin repellency in Aedes aegypti.

PLoS Negl Trop Dis

July 2021

Department of Entomology, Michigan State University, East Lansing, Michigan, United States of America.

Background: Volatile pyrethroid insecticides, such as transfluthrin, have received increasing attention for their potent repellent activities in recent years for controlling human disease vectors. It has been long understood that pyrethroids kill insects by promoting activation and inhibiting inactivation of voltage-gated sodium channels. However, the mechanism of pyrethroid repellency remains poorly understood and controversial.

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Pyrethrum extract from dry flowers of Tanacetum cinerariifolium (formally Chrysanthemum cinerariifolium) has been used globally as a popular insect repellent against arthropod pests for thousands of years. However, the mechanistic basis of pyrethrum repellency remains unknown. In this study, we found that pyrethrum spatially repels and activates olfactory responses in Drosophila melanogaster, a genetically tractable model insect, and the closely-related D.

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Keystone taxa-mediated bacteriome response shapes the resilience of the paddy ecosystem to fungicide triadimefon contamination.

J Hazard Mater

September 2021

Institute of Pesticide and Environmental Toxicology, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou 310058, China; Global Education Program for AgriScience Frontiers, Graduate School of Agriculture, Hokkaido University, Sapporo 060-8589, Japan. Electronic address:

The increasing input of fungicides has emerged as a global concern for agroecosystem stability and sustainability. Agroecosystem resilience has been linked to microbiome response, however, is not well understood. Focusing on a widespread triazole-class fungicide triadimefon in the paddy ecosystem, we characterized that the soils and sediments were dominant triadimefon reservoirs with the peak level at 195 μg kg and 31.

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PXR-mediated organophorous flame retardant tricresyl phosphate effects on lipid homeostasis.

Chemosphere

December 2021

Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, 310058, PR China. Electronic address:

An emerging experimental framework suggests that endocrine-disrupting compounds are candidate obesogens. However, this potential effect has not yet been determined for Tricresyl phosphate (TCP), a mass-produced organophosphate flame retardant (OPFR) that has been exposed to human beings in many ways. Many OPFRs, including TCP, have been shown to activate pregnane X receptor (PXR), a nuclear receptor that regulates lipid metabolism.

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Direct and indirect effects of fenoxycarb on freshwater systems dominated by Neocaridina palmata (Decapoda: Atyidae) and macrophyte Ceratophyllum demersum.

Ecotoxicol Environ Saf

August 2021

Institute of Pesticide and Environmental Toxicology, Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Zhejiang University, Hangzhou 310058, PR China.

Few studies have been conducted with regard to the effects of insecticides on population dynamics of shrimps and associated groups such as macrophytes, phytoplankton, microorganisms etc. In the present study, effects of a single application of fenoxycarb were tested using indoor freshwater systems dominated by Neocaridina palmata and Ceratophyllum demersum (Dicotyledons: Ceratophyllales). The no observed effect concentration (NOEC) and lowest observed effect concentration (LOEC) for the N.

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Pyrethrum extracts from flower heads of Chrysanthemum spp. have been used worldwide in insecticides and repellents. While the molecular mechanisms of its insecticidal action are known, the molecular basis of pyrethrum repellency remains a mystery.

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Bis(2-ethylhexyl)-2,3,4,5-tetrabromophthalate (TBPH), a novel brominated flame retardant, can potentially cause lipid metabolism disorder; however, its biological effects on lipid homeostasis remain unknown. We investigated its ability to cause nonalcoholic fatty liver disease (NAFLD) in zebrafish. Female zebrafish were fed a high-fat diet (HFD, 24% crude fat) or normal diet (ND, 6% crude fat), and exposed to TBPH (0.

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Novel immunochromatographic strip assay based on up-conversion nanoparticles for sensitive detection of imidacloprid in agricultural and environmental samples.

Environ Sci Pollut Res Int

September 2021

Institute of Pesticide and Environmental Toxicology, Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Zhejiang University, Hangzhou, 310058, China.

Neonicotinoid insecticides are widely used in agriculture for pest control, but the pesticide residues in environmental and agricultural products were a big threat to the health of non-target organisms. In this study, a new immunochromatographic strip test was established for the rapid detection of imidacloprid residue, a neonicotinoid insecticide, based on up-conversion nanoparticles (UCNPs) coupled with the monoclonal antibody against imidacloprid. Under optimal conditions, the half inhibitory concentration (IC), detection limit, and the linear range of this strip were 8.

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A Light-Triggered pH-Responsive Metal-Organic Framework for Smart Delivery of Fungicide to Control Sclerotinia Diseases of Oilseed Rape.

ACS Nano

April 2021

Institute of Pesticide and Environmental Toxicology, Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Zhejiang University, Hangzhou 310058, P.R. China.

Using a simple one-pot method, we developed a prochloraz (Pro) and pH-jump reagent-loaded zeolitic imidazolate framework-8 (PD@ZIF-8) composite for the smart control of Sclerotinia disease. The pH-jump reagent can induce the acidic degradation of ZIF-8 using UV light to realize the controlled release of Pro. Thus, the physical properties of PD@ZIF-8, such as its release, formulation stability, and adhesion, were investigated in detail.

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Pyrethrins elicit olfactory response and spatial repellency in Aedes albopictus.

Pest Manag Sci

August 2021

Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, China.

Article Synopsis
  • Pyrethrum, derived from Chrysanthemum flowers, is an established botanical insecticide known for its six insecticidal esters, collectively called pyrethrins, which impact sodium channels in insects and are effective for repelling mosquitoes.
  • Recent research showed that pyrethrum vapor caused non-contact repellency in Aedes albopictus mosquitoes, with dose-dependent responses recorded in their antennae.
  • Out of the six pyrethrins isolated, four (pyrethrins I and II, cinerin II, and jasmolin II) triggered spatial repellency by activating specific olfactory-receptor neurons, suggesting a pathway for enhancing mosquito repellent effectiveness in controlling mosquito-borne diseases.
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Reduced bacterial network complexity in agricultural soils after application of the neonicotinoid insecticide thiamethoxam.

Environ Pollut

April 2021

Institute of Pesticide and Environmental Toxicology, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou, 310058, China. Electronic address:

Pesticides may alter soil microbial community structure or diversity, but their impact on microbial co-occurrence patterns remains unclear. Here, the effect of the widely used neonicotinoid insecticide thiamethoxam on the bacterial community in five arable soils was deciphered using the 16S rRNA gene amplicon sequencing technique. The degradation half-life of thiamethoxam in nonsterilized soils was significantly lower than that in sterilized soils, suggesting a considerable contribution from biodegradation.

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Bacterial seed endophyte shapes disease resistance in rice.

Nat Plants

January 2021

Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Ministry of Agriculture, Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, China.

Article Synopsis
  • - Cereal crops globally suffer from seed-borne bacterial diseases, and while disease resistance in crops is difficult to find, research reveals that some rice plants show both disease-resistant and susceptible traits under the same pathogen pressure.
  • - A specific bacterium, Sphingomonas melonis, found in disease-resistant rice seeds, was identified as key to conferring resistance by producing anthranilic acid, which disrupts disease-causing bacteria's ability to produce virulence factors without harming plant growth.
  • - These findings emphasize the significance of seed endophytes in the interactions among plants, pathogens, and environmental factors, suggesting valuable avenues for improving crop resistance against widespread bacterial diseases.
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Foam shares antibiotic resistomes and bacterial pathogens with activated sludge in wastewater treatment plants.

J Hazard Mater

April 2021

Institute of Pesticide and Environmental Toxicology, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou 310058, China; Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Ministry of Agriculture, Zhejiang University, Hangzhou 310058, China; Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, Zhejiang University, Hangzhou 310058, China. Electronic address:

Foaming is a common operational problem that occurs in activated sludge (AS) from many wastewater treatment plants (WWTPs), but the characteristic of antibiotic resistance genes (ARGs) and human pathogenic bacteria (HPB) in foams is generally lacking. Here, we used a metagenomic approach to characterize the profile of ARGs and HPB in foams and AS from full-scale WWTPs receiving pesticide wastewater. No significant difference in the microbial communities was noted between the AS and foam samples.

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The combined adverse effects of cis-bifenthrin and graphene oxide on lipid homeostasis in Xenopus laevis.

J Hazard Mater

April 2021

Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou 310058, China. Electronic address:

Simultaneous exposure to multiple pollutants has received great concerns considering that the interactions between pollutants can alter the environment fate and bioavailability of pollutants with potentially deleterious effects. Graphene oxide (GO) has been widely used in many areas including environmental remediation, biology and agriculture. However, researchers have largely ignored the combined toxicity of GO with coexisting toxicants.

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Determination and Dietary Intake Risk Assessment of Pesticide Residues in Fritillariae Thunbergii Bulbs and Cultivated Soils.

J AOAC Int

May 2021

Institute of Pesticide and Environmental Toxicology, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, China.

Background: Pesticide residues in traditional Chinese medicines pose a potential risk to human health. However, little is known about the characteristics of pesticide residues in the fritillariae thunbergii bulbs (FTB).

Objective: This study aims to establish a method for the determination of pesticide multi-residues in FTB and then measured their residual levels in the FTB collected from nine cultivation regions.

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Crosstalk of cholinergic pathway on thyroid disrupting effects of the insecticide chlorpyrifos in zebrafish (Danio rerio).

Sci Total Environ

February 2021

Ministry of Agriculture Key Laboratory of Molecular Biology of Crop Pathogens and Insect Pests, Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou 310058, PR China.

Chlorpyrifos is a widely used organophosphate insecticide and ubiquitously detected in the environment. However, little attention has been paid to its endocrine disrupting effect to non-target organisms. In the present study, zebrafish was exposed to 13 and 65 μg/L of chlorpyrifos for 7 and 10 days to determine the induced neurotoxicity and the alteration of thyroid metabolism.

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Recent Trends in Nanomaterial-Based Biosensors for Point-of-Care Testing.

Front Chem

October 2020

Institute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou, China.

In recent years, nanomaterials of different shape, size, and composition have been prepared and characterized, such as gold and silver nanoparticles, quantum dots, mesoporous silica nanoparticles, carbon nanomaterials, and hybrid nanocomposites. Because of their unique physical and chemical properties, these nanomaterials are increasingly used in point-of-care testing (POCT) to improve analytical performance and simplify detection process. They are used either as carriers for immobilizing biorecognition elements, or as labels for signal generation, transduction and amplification.

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Exposure to fungicide difenoconazole reduces the soil bacterial community diversity and the co-occurrence network complexity.

J Hazard Mater

March 2021

Institute of Pesticide and Environmental Toxicology, College of Agriculture & Biotechnology, Zhejiang University, Hangzhou 310058, China; Key Laboratory of Molecular Biology of Crop Pathogens and Insects, Ministry of Agriculture, Zhejiang University, Hangzhou 310058, China; Key Laboratory of Biology of Crop Pathogens and Insects of Zhejiang Province, Zhejiang University, Hangzhou 310058, China. Electronic address:

Difenoconazole is a triazole fungicide that is widely used worldwide and has been frequently detected in agricultural soils, but its ecotoxicological effect on soil bacterial community remains unknown. Here, the degradation of difenoconazole and its effect on soil bacterial communities were investigated at three concentrations in five different agricultural soils. Difenoconazole degraded faster in non-sterilized soils than in sterilized soils, suggesting that biodegradation is a major contributor to the dissipation of difenoconazole in soils.

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Chemical factors affecting uptake and translocation of six pesticides in soil by maize (Zea mays L.).

J Hazard Mater

March 2021

Institute of Pesticide and Environmental Toxicology, the Key Laboratory of Molecular Biology of Crop Pathogens and Insects, College of Agricultural and Biotechnology, Zhejiang University, Hangzhou 310058, China. Electronic address:

Uptake of residual pesticides in a soil by a certain crop plant may be governed by their physicochemical properties. Uptake and translocation of pesticides (imidacloprid, acetamiprid, tricyclazole, azoxystrobin, tebuconazole and difenoconazole) with the octanol/water partition coefficient (log K) ranging from 0.57 to 4.

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3D, eco-friendly metal-organic frameworks@carbon nanotube aerogels composite materials for removal of pesticides in water.

J Hazard Mater

January 2021

Institute of Pesticide and Environmental Toxicology, Ministry of Agriculture Key Lab of Molecular Biology of Crop Pathogens and Insects, Zhejiang University, Hangzhou 310058, PR China. Electronic address:

To alleviate the secondary risks of using metal-organic frameworks (MOFs) nanoparticles as adsorbent, a novel method of loading two MOFs (ZIF-8 or UiO66-NH) on the carbon nanotube aerogels (MPCA) by in situ nucleation and growth of MOFs nanoparticles onto carbon nanotubes were developed. The prepared MOFs@MPCA aerogels were well characterized via SEM, TEM, EDS, FT-IR, XRD and XPS to reveal the microstructure and formation mechanism of MOF@MPCA. Besides, the hydrophilia, mechanical property and thermostability of MOF@MPCA were investigated.

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Competitive Adsorption and Mobility of Propiconazole and Difenoconazole on Five Different Soils.

Bull Environ Contam Toxicol

December 2020

Institute of Pesticide and Environmental Toxicology, The Key Laboratory of Molecular Biology of Crop Pathogens and Insects, College of Agricultural and Biotechnology, Zhejiang University, Hangzhou, 310058, China.

Propiconazole (PPC) and difenoconazole (DFC) are often combined for field applications. The resulted co-exsistence of PPC and DFC may have an effect on the fate of their individuals in soil. In this study, adsorption, desorption and leaching of PPC and DFC alone and their combinations were investigated in five different soils.

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