583 results match your criteria: "Institute of Oral Health[Affiliation]"

This study investigated the efficacy and safety of a propolis-mangosteen extract complex (PMEC) on gingival health in patients with gingivitis and incipient periodontitis. A multicentered, randomized, double-blind, placebo-controlled trial involving 104 subjects receiving either PMEC or placebo for eight weeks was conducted. The primary focus was on the changes in inflammatory biomarkers from gingival crevicular fluid (GCF), with clinical parameters as secondary outcomes.

View Article and Find Full Text PDF
Article Synopsis
  • Oxidative stress arises when there's an imbalance between prooxidants and antioxidants, and celecoxib, a COX-2 inhibitor, can cause oxidative harm to the liver despite its effectiveness in reducing pain and inflammation.
  • The study tested the hypothesis that lycopene, a natural antioxidant found in certain fruits and vegetables, could protect rat liver cells from damage caused by celecoxib, through a controlled experiment with three groups of rats receiving different treatments.
  • Results indicated that lycopene effectively reduced liver damage and prevented fat accumulation and glycogen depletion in rats treated with celecoxib, suggesting it may offer protective benefits against oxidative injury and related liver diseases.
View Article and Find Full Text PDF

Systemic Factors Affecting Pain Management in Dentistry.

Dent Clin North Am

October 2024

Orofacial Pain and Temporomandibular Disorders, Eastman Institute of Oral Health, Rochester, NY 14620, USA. Electronic address:

There are several factors that affect a patient's experience of pain. These include both local and systemic factors. The systemic factors that affect patients' dental and orofacial pain experience include, but not limited to, hormonal, nutritional, systemic infections, neurodegenerative, and autoimmune, among others.

View Article and Find Full Text PDF

This article explores the intersection of various systemic conditions with orthodontic treatment. Renal diseases, including chronic kidney disease and renal transplant, present challenges such as delayed tooth eruption and gingival overgrowth, necessitating careful orthodontic planning and collaboration with physicians. Liver diseases, particularly hepatitis, heighten the risk of periodontal disease and mandate strict infection control measures during orthodontic procedures.

View Article and Find Full Text PDF

Background: Dental students face the rigorous demands of coursework, which can lead to feelings of inadequacy and stress. These pressures can negatively influence self-efficacy and cause neglect in practicing healthy behaviors that encompass oral health. Identifying the associations of these variables with oral hygiene practices can help in the formulation of interventions tailored toward supporting young students.

View Article and Find Full Text PDF

Applications of 3D-printed teeth in dental education: A narrative review.

J Taibah Univ Med Sci

August 2024

Department of Oral Biology, Sindh Institute of Oral Health Sciences, Jinnah Sindh Medical University, Karachi, Pakistan.

Background: The contemporary era of education prompts the need for innovation that facilitates the comprehensible and immersive learning of students. Three-dimensional (3D) printing or additive manufacturing in the form of 3D-printed teeth provides an attractive alternative to extracted teeth and standard dental models, as they provide educational equality and realistic simulation of natural teeth.

Aim: This review article summarises the literature that has proven the role and effectiveness of 3D-printed teeth in dental education.

View Article and Find Full Text PDF

Statement Of Problem: Limited studies have reported the influence of finish line location on the accuracy of intraoral scanners (IOSs). Focal length is a hardware characteristic of IOSs. Whether there is a relationship between scanning accuracy of tooth preparations with the finish located at different apical positions and focal length and IOS technology or system remains uncertain.

View Article and Find Full Text PDF

Influence of scanning pattern on accuracy, time, and number of photograms of complete-arch implant scans: A clinical study.

J Dent

November 2024

Affiliate Assistant Professor, Graduate Prosthodontics, Department of Restorative Dentistry, School of Dentistry, University of Washington, Seattle, WA; Faculty and Director of Research and Digital Dentistry, Kois Center, Seattle, WA; and Adjunct Professor, Department of Prosthodontics, School of Dental Medicine, Tufts University, Boston, MA, USA.

Objectives: To measure the influence of scanning pattern on the accuracy, time, and number of photograms of complete-arch intraoral implant scans.

Methods: A maxillary edentulous patient with 7 implants was selected. The reference implant cast was obtained using conventional methods (7Series Scanner).

View Article and Find Full Text PDF
Article Synopsis
  • * Results showed significant over-transmission of specific gene variants in both Korean families and larger datasets from Asian and European populations, highlighting four variants with strong associations to NSCL/P.
  • * The analysis also indicated that certain alleles were more likely to be passed from mothers, suggesting a potential maternal influence in the genetic transmission of the condition; further research is needed to explore how these findings could be applied clinically.
View Article and Find Full Text PDF

Discrepancies of centric occlusion located by using a conventional method and four intraoral scanners combined with a computer-aided design program: A pilot investigation.

J Prosthet Dent

July 2024

Founder and Director, Kois Center, Seattle, Wash.; Affiliate Professor, Graduate Prosthodontics, Department of Restorative Dentistry, University of Washington, Seattle, Wash.; and Private practice, Seattle.

Statement Of Problem: Intraoral scanners (IOSs) can be used to record the maxillomandibular relationship at centric relation (CR). The articulated digital scans can be imported into a dental computer-aided design (CAD) program and used to locate centric occlusion (CO); however, the accuracy of the CO recorded by using IOSs and a dental CAD program remains unknown.

Purpose: The purpose of this clinical study was to compare the position of the CO located by using a conventional method and 4 IOSs combined with a dental CAD program.

View Article and Find Full Text PDF

Objectives: The objective of this study was to evaluate the effect of acidic beverages on the surface topography and elemental composition of human teeth.

Methods: A total of five highly acidic beverages (Red Bull, Pepsi, Apple Cidra, Tang Mosambi, and Tang Orange) were investigated. The tooth specimens of experimental groups were submerged in each beverage and incubated at 37 °C for 7 days, whereas, the tooth specimens of control groups were placed in distilled water.

View Article and Find Full Text PDF

Objective: Early Childhood Caries (ECC) is prevalent among preschool children. The aim was to assess the effectiveness of an intervention to modify family-level determinants of caries (i.e.

View Article and Find Full Text PDF

An updated review and recent advancements in carbon-based bioactive coatings for dental implant applications.

J Adv Res

July 2024

Department of Restorative Dentistry, College of Dentistry, Taibah University, Al Madina Al Munawwarrah 41311, Saudi Arabia; Centre of Medical and Bio-allied Health Sciences Research, Ajman University, Ajman, 346, United Arab Emirates; School of Dentistry, University of Jordan, Amman 11942, Jordan; Department of Dental Materials, Islamic International Dental College, Riphah International University, Islamabad 44000, Pakistan. Electronic address:

Background: Surface coating of dental implants with a bioactive biomaterial is one of the distinguished approaches to improve the osseointegration potential, antibacterial properties, durability, and clinical success rate of dental implants. Carbon-based bioactive coatings, a unique class of biomaterial that possesses excellent mechanical properties, high chemical and thermal stability, osteoconductivity, corrosion resistance, and biocompatibility, have been utilized successfully for this purpose.

Aim: This review aims to present a comprehensive overview of the structure, properties, coating techniques, and application of the various carbon-based coatings for dental implant applicationswith a particular focuson Carbon-based nanomaterial (CNMs), which is an advanced class of biomaterials.

View Article and Find Full Text PDF

Objective: To determine the relationship of anterior occlusion and skeletal variables with the frontal sinus index.

Methods: The retrospective, analytical, cross-sectional, study was conducted from July to November 2020 at Dr Ishratul- Ebad Khan Institute of Oral Health Sciences and Dow Dental College, Dow University of Health Sciences, Karachi, and comprised data from 2015 to 2018 related to pre-treatment lateral cephalograms for determining frontal sinus index and other cephalometric variables. The dental casts were observed for incisor classification.

View Article and Find Full Text PDF

Objective: To determine characteristics and motivational factors of applicants applying for MHPE program at a Public-sector University, Karachi.

Methods: This cross-sectional descriptive study, conducted from September till October 2022, included all 60 applicants of MHPE program at Jinnah Sindh Medical University. The survey questionnaire was administered (google form) and comprised questions seeking demographic information, few questions with options to select and 34 statements to be responded on 5-point scale.

View Article and Find Full Text PDF

Comparison of virtual clinical scenario and role play in learning oral pathology among dental students.

PLoS One

July 2024

Department of Oral Pathology, Dr. Ishrat-ul-Ebad Khan Institute of Oral Health Sciences, Dow University of Health Sciences, Karachi, Pakistan.

In oral pathology, virtual clinical scenario illustrating dentist-patient interactions can be utilized by both students and health professionals to deliver/gain knowledge and make clinical diagnosis of oral lesions. Role play is also an educational technique which is designed to engage and motivate students in classrooms. This study aimed to compare usefulness of virtual clinical scenario and role play in learning oral pathology among second-year dental students.

View Article and Find Full Text PDF

Background: Radiotherapy is used to treat oral cancer, yet it negatively affects patients' health-related quality of life (HRQOL). The aim was to evaluate the impact of an oral healthcare intervention on HRQOL of patients with oral cancer who receive radiotherapy with or without chemotherapy.

Methods: An oral healthcare intervention was provided to 41 patients with oral cancer before radiotherapy (fluoride varnish application, scaling, permanent restorations, adjustment of sharp teeth, and extraction of teeth with questionable prognosis, oral hygiene instructions), during, and 3 months after radiotherapy (baking soda mouthwash, artificial saliva spray).

View Article and Find Full Text PDF

Objectives: This study aimed to investigate the performance and reliability of data-driven models employing correlational feature analysis and clinical validation for predicting periodontal disease.

Methods: The 7th Korea National Health and Nutrition Examination Survey ( = 10,654) was used for correlation analysis to identify significant risk factors for periodontitis. Periodontal prediction models were developed with the selected factors and database, followed by internal validation with 5-fold cross-validation and 1000 bootstrap resampling.

View Article and Find Full Text PDF

Objective: To determine the relationship of Neutrophil Lymphocyte Ratio (NLR), Monocyte Lymphocyte Ratio (MLR), and Neutrophil Monocyte Ratio (NMR) with treatment response in Pulmonary Tuberculosis (PTB) patients during intensive phase treatment (IPT).

Methods: This analytical cross-sectional study was conducted at Ojha Institute of Chest Diseases (OICD), Dow University of Health Sciences, from February to December 2021. 100 patients were enrolled using purposive sampling technique.

View Article and Find Full Text PDF

Non-syndromic orofacial clefts (NSOFCs) are common birth defects with a complex etiology. While over 60 common risk loci have been identified, they explain only a small proportion of the heritability for NSOFCs. Rare variants have been implicated in the missing heritability.

View Article and Find Full Text PDF

Objective: Bibliometric analysis and citation counts help to acknowledge influence of publications. The aim of this study was to conduct bibliometric and citation analysis of top-cited articles, from low- and lower-middle income countries, on use and application of digital technology in dentistry.

Methodology: A search strategy based on "Digital Dentistry", "Low Income Countries", and "Lower-Middle Income Countries" was used in October 2023 using Scopus database to retrieve articles relevant to digital dentistry, with citation count of 10 or more.

View Article and Find Full Text PDF

Comparison of the effect of propolis and Gluma desensitizer on the management of dentin hypersensitivity: A randomized controlled trial.

J Pak Med Assoc

May 2024

Department of Operative Dentistry, Dr. Ishrat ul Ebad Khan Institute of Oral Health Sciences, Dow University of Health Sciences, Karachi, Pakistan.

Objective: To compare the effect of propolis and gluma desensitisers on the management of dentin hypersensitivity.

Methods: The single-blind, randomised controlled trial was conducted at the Department of Operative Dentistry, Dr Ishrat ul Ebad Khan Institute of Oral Health Sciences, Dow University of Health Sciences, Karachi, from October 2020 to September 2021, and comprised patients with dentin hypersensitivity who had pain scores of at least 2 on the visual analogue scale. The teeth were randomised into propolis group A and Gluma group B.

View Article and Find Full Text PDF

Objective: To compare the procrastination and self-efficacy scores among students with respect to the academic year of dental undergraduate programme, and to assess the relationship between self-efficacy and academic procrastination among the students.

Methods: The descriptive study was conducted at Sindh Institute of Oral Health Sciences, Jinnah Sindh Medical University, Karachi, from January to March 2023, and comprised medical students of either gender from all the 4 academic years. Data was collected using a structured questionnaire whose validity was assessed using a pilot study.

View Article and Find Full Text PDF

Background: Dentin hypersensitivity (DH) is one of the most challenging and persistent dental complaints characterized by transient, intense pain triggered by various stimuli. It affects a significant portion of the global population, predominantly those aged 20-40. This study aims to evaluate the desensitizing efficacy of seventh-generation dentin bonding agents (Single Bond Universal by 3 M ESPE and Xeno-V + by Dentsply) against a control group using Bifluorid 12 by Voco in mitigating DH within a month of the follow-up period.

View Article and Find Full Text PDF

Chitosan-based materials for dental implantology: A comprehensive review.

Int J Biol Macromol

May 2024

Department of Restorative Dentistry, College of Dentistry, Taibah University, Al Madinah, Al Munawwarah, Saudi Arabia; Centre of Medical and Bio-allied Health Sciences Research, Ajman University, Ajman, Ajman 346, United Arab Emirates; School of Dentistry, University of Jordan, Amman, Jordan; Department of Dental Materials, Islamic International College, Riphah International University, Islamabad, Pakistan. Electronic address:

Chitosan, a versatile biopolymer, has gained recognition in the discipline of dental implantology due to possessing salient properties. This comprehensive review explores the potential of chitosan in dental implants, focusing on its biocompatibility, bioactivity, and the various chitosan-based materials that have been utilized for dental implant therapy. The review also highlights the importance of surface treatment in dental implants to enhance osseointegration and inhibit bacterial biofilm formation.

View Article and Find Full Text PDF