1,985 results match your criteria: "Institute of Nutrition and Food Technology[Affiliation]"

Live cultures, including Nannochloropsis oculata and Brachionus plicatilis, are essential in aquaculture due to its economic and nutritional value for commercial fish species. Pathogens and probiotics can be introduced to aquaculture systems by live feed, with variations in abundance influenced by environmental physicochemical parameters. To investigate this, amplicon sequencing of the V3-V4 region of the 16S rRNA was conducted using Illumina MiSeq to elucidate bacterial abundances and their variations in response to changes in physicochemical parameters in live feed cultures.

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Sexual dimorphism on the acute effect of exercise in the morning vs. evening: A randomized crossover study.

J Sport Health Sci

December 2024

Department of Physiology, University of Granada, Granada 18071, Spain; Instituto de Investigación Biosanitaria (ibs.Granada), Granada 18014, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Granada 18071, Spain.

Background: Mammalian cells possess molecular clocks, the adequate functioning of which is decisive for metabolic health. Exercise is known to modulate these clocks, potentially having distinct effects on metabolism depending on the time of day. This study aimed to investigate the impact of morning vs.

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The One Health concept, although formulated two decades ago, remains challenging to implement. It necessitates the integration of numerous scientific disciplines, diverse techniques and various professional expertise. Furthermore, it often requires the collaboration of different institutions, encompassing both scientific and administrative entities.

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Background: Higher life expectancy has produced a higher older people porpulation, not necessarily with a consistent quality of life, showing a high rate of vulnerability and dependence. The current social and health crisis situation has highlighted the need to create new integrated models of care that could be translated into social and health policies.

Objective: The present study aims to develop, test, and validate an innovative integrated care model for older people with dependence and at risk of social exclusion and their caregivers.

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Introduction: Chile has achieved developed nation status and boasts a life expectancy of 81 + years; however, the healthcare and research systems are unprepared for the social and economic burden of cancer. One decade ago, the authors put forward a comprehensive analysis of cancer infrastructure, together with a series of suggestions on research orientated political policy.

Objectives: Provide an update and comment on policy, infrastructure, gender equality, stakeholder participation and new challenges in national oncology.

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Article Synopsis
  • Previous models for predicting weight gain haven't been very effective, leading researchers to explore both traditional environmental factors and genetic markers to enhance accuracy.* -
  • A study involving nearly 246,000 participants found that environmental factors provided good predictive ability for weight gain, while genetic models performed poorly, especially at mid-late adulthood.* -
  • The research suggests that environmental factors should be incorporated into prevention strategies, and that genetic factors may be more relevant in predicting weight gain earlier in life.*
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  • Frozen shoulder (FS) is a painful condition that limits shoulder movement, and this study looks at how liver enzymes and thyroid function relate to pain and shoulder function in FS patients.
  • Researchers evaluated 32 patients' metabolic biomarkers through blood tests and assessed pain and functionality using the Shoulder Pain and Disability Index (SPADI).
  • The study found that lower levels of certain liver enzymes (AST, ALT, GGT) and thyroid-stimulating hormone (TSH) were associated with higher pain scores, indicating that these metabolic factors may influence the severity of FS symptoms.
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  • - Neurodegenerative diseases, like Alzheimer's and Parkinson's, lead to neuron loss and significantly impact many lives, prompting the search for new therapies beyond current medications.
  • - Magnesium (Mg) is an essential mineral important for central nervous system health, but its specific role in human neurodegenerative diseases is not well understood.
  • - This review explores the connection between Mg levels and neurodegenerative disorders by analyzing biological samples from patients and animal model studies, suggesting that Mg may have neuroprotective properties; however, further research is needed for clarity on its therapeutic use.
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  • The Cucurbitaceae family, known for its bioactive compounds, is being studied for its potential in preventing and treating colorectal cancer (CRC).
  • Four different extracts from cucurbit leaves and seeds were tested on various CRC cell lines to evaluate their effects on tumor growth and cell health.
  • Cold ethanolic extracts showed significant anti-cancer properties, such as inhibiting cell proliferation and angiogenesis, and were linked to specific cell cycle changes and gene expression modifications, suggesting they could enhance CRC treatment strategies.
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  • Diet has a significant impact on gut microbiota, highlighting the need for personalized nutrition based on individual dietary habits.
  • The Stance4Health project created the S4H Food Frequency Questionnaire and i-Diet S4H app to evaluate food intake related to gut microbiota.
  • Validation studies showed the S4H-FFQ reliably estimates dietary patterns, correlating well with another validated questionnaire and indicating its potential for enhancing personalized nutrition and health research.
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  • * The study focused on the relationship between long-term dietary mycotoxin exposure and hepatobiliary cancers in the EPIC cohort, using detailed food occurrence data to assess risks.
  • * Findings indicated a significant link between higher intake of the mycotoxin deoxynivalenol (DON) and hepatocellular carcinoma risk, suggesting further research is needed on mycotoxins and their potential health impacts.
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Background & Aims: Expression of P21, encoded by the gene, has been associated with fibrosis progression in steatotic liver disease (SLD); however, the underlying mechanisms remain unknown. In the present study, we investigated the function of CDKN1A in SLD.

Methods: expression levels were evaluated in different patient cohorts with SLD, fibrosis, and advanced chronic liver disease (ACLD).

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Effects of infant feeding type on auditory event-related potentials at 24 months of age.

Pediatr Res

December 2024

Sleep and Functional Neurobiology Laboratory, Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.

Background: Added bovine milk fat globule membrane (bMFGM) or bMFGM components in infant formulas may favor language development essential for cognitive maturation in early life. In this study, the influence of infant feeding type on language skills acquisition was investigated.

Methods: Auditory event-related potentials (ERPs) were performed at ~4-6 (baseline) and 24 months of age in infants receiving: human milk, as a reference group (HM, n = 42) or randomized to standard infant formula (SF, n = 53) or similar formula with added bMFGM (EF, n = 48) through 12 months of age.

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Overweight/obesity (OW/OB) have been associated with gut dysbiosis, changes in gastrointestinal motility and sedentary behavior, contributing to metabolic and inflammatory alterations. This systematic review aims to assess the evidence supporting the influence of physical activity and exercise on gut microbiota composition and diversity in OW/OB and was conducted according to PRISMA guidelines, using Medline, Embase, Ebsco and Scopus databases. Risk of bias was assessed with RoB 2 for randomized controlled trials (RCT), ROBINS-I for non-RCT and JBI Critical Appraisal tool for cross-sectional studies.

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Article Synopsis
  • Prenatal nutrition, particularly maternal choline intake, is essential for fetal development, affecting gene expression and brain structure.
  • Studies show that adequate choline consumption can enhance the development of brain regions like the cerebral cortex and hippocampus, and it may help reduce the risk of neurodevelopmental disorders.
  • The review emphasizes the need for more research on the timing, dosage, and mechanisms of choline's effects, particularly concerning conditions like Rett syndrome, fragile X syndrome, and Down syndrome.
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Efficiency of IL-6 in Early Prognosis and Follow-Up in Critically Ill Patients with Septic Shock.

Diseases

November 2024

Department of Physiology, School of Pharmacy, Institute of Nutrition and Food Technology "José Mataix", University of Granada, 18071 Granada, Spain.

Article Synopsis
  • The study investigated the response of interleukin-6 (IL-6) in critically ill patients with septic shock during their initial hours in the ICU, comparing it to healthy subjects.
  • Results showed that IL-6 levels were significantly higher in septic shock patients upon ICU admission and decreased after three days, indicating a potential link to recovery.
  • The study also found strong correlations between IL-6 and other biomarkers, suggesting that IL-6 could serve as an important prognostic marker for monitoring septic shock in ICU patients within the first 72 hours of their stay.
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  • Antibiotics are essential for treating infections and preventing illness, but their use, especially in infants, can lead to long-term health issues due to changes in gut microbiota.
  • The disruption of gut microbiota, known as gut dysbiosis, is linked to various chronic diseases like obesity, diabetes, autoimmune disorders, and some cancers.
  • Probiotics may help counteract the negative effects of gut dysbiosis in patients with chronic diseases, potentially improving their health and inflammation markers.
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  • - The study investigates the nutritional status of breast cancer patients undergoing chemotherapy and explores how nutrition affects the severity of chemotherapy-related digestive issues.
  • - Conducted on 107 women with an average age of 52, the study found that 41% were malnourished, 80% experienced constipation, and strong adherence to a Mediterranean diet was linked to less severe nausea and constipation.
  • - The results emphasize the importance of early nutritional intervention to enhance the tolerance and effectiveness of chemotherapy treatments in breast cancer patients.
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Tunis Med

November 2024

Research Unit UR18ES01 'Obesity: aetiopathogeny, pathophysiology and treatment', Faculty of Medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.

Introduction: Childhood obesity, a true international epidemic, is a multifactorial pathology including genetic and environmental factors.

Aim: Determine the prevalence and risk factors of overweight in Tunisian schoolchildren in the Bardo region, an urban department of the Tunis governorate.

Methods: Descriptive and cross-sectional study involving schoolchildren aged between 10 and 12 years old.

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The ice plant ( L.) is a halophyte that could become an alternative crop because of its interest as a functional food and its adaptation to high-saline soils. In this work, leaves from wild ice plants were compared with their cultivated counterparts in a soilless system at different salinities and light exposures for assessing growth parameters, moisture, fatty acid profiles, total carotenoids, phenolic compounds, vitamin C, antioxidant activity, and antiproliferative activity against the HT-29 colorectal cancer cell line.

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Background: Nutri-Score is a scientifically validated 5-color front-of-pack nutrition label reflecting the nutrient profile of foods. It has been implemented in several European countries on a voluntary basis, pending the revision of the European labeling regulation. Hence, scientific evidence is needed regarding the ability of the nutrient profile underlying the Nutri-Score (uNS-NPS, 2023-updated version) to characterize healthier foods.

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Associations between the prevalence of asthma and dietary exposure to food contaminants in children: CHASER study.

World J Pediatr

December 2024

Department of Nutrition and Food Science, Institute of Nutrition and Food Technology, Biomedical Research Centre, University of Granada, 18071, Granada, Spain.

Background: Asthma is a common, multifactorial chronic disease with a major impact on children and adolescents. Exposure to food contaminants is one of the contributing factors to asthma. This study aims to evaluate the intake and exposure of different contaminants and explore their association with childhood asthma.

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Prevention of cardiometabolic diseases through dietary modifications.

Curr Opin Lipidol

November 2024

Department of Biochemistry and Molecular Biology II, Faculty of Pharmacy, Centre for Biomedical Research, Institute of Nutrition and Food Technology, Universidad de Granada, Spain.

Purpose Of Review: Cardiometabolic diseases (CMDs) increasingly contribute to the cumulative burden of morbidity and mortality worldwide. Here, we reviewed intervention studies using a randomized controlled trial (RCT) design as well as meta-analyses of RCTs aimed at testing the effectiveness of different dietary approaches for CMD prevention.

Recent Findings: Recent studies testing dietary approaches for CMD prevention were summarized narratively, with a focus on interventions based on caloric restriction and fasting, healthy dietary patterns and food-based dietary modifications.

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Article Synopsis
  • - The study investigates the role of the Pyk2 gene in obesity among children and adolescents, noting its previously unclear involvement in energy balance-related diseases.
  • - Researchers measured mRNA expression levels of Pyk2 in 130 Caucasian subjects, split into two groups based on Body Mass Index (BMI), and found higher expression levels in those with obesity.
  • - The results revealed a positive correlation between Pyk2 expression levels and various obesity-related metrics (like weight, fat mass, and blood pressure), suggesting that Pyk2 may be a potential predictor for developing obesity.
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In this cross-sectional study, we explored the influence of Mediterranean Diet (MD) adherence and physical activity-related energy expenditure on weight status and cardiometabolic risk in a large sample of 2.833 young, middle-aged and older adults. A food frequency questionnaire was employed, and to assess MD adherence.

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