2 results match your criteria: "Institute of Nuclear Sciences Applied To Health - University of Coimbra[Affiliation]"
Rosuvastatin effect on atherosclerotic plaque metabolism: A subclinical atherosclerosis imaging study with F-NaF PET-CT.
Atherosclerosis
August 2024
Cardiology Department, Unidade Local de Saúde de Coimbra, Centro Hospitalar e Universitário de Coimbra, Praceta Prof. Mota Pinto, 3000-075, Coimbra, Portugal; Institute of Nuclear Sciences Applied to Health - University of Coimbra, Azinhaga de Santa Comba, 3000-548, Coimbra, Portugal; Faculty of Medicine, University of Coimbra, Rua Larga, 3004-504, Coimbra, Portugal; Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), Azinhaga de Santa Comba, 3000-548 Coimbra, Portugal.
Background And Aims: Atherosclerotic plaque fluorine-18 sodium fluoride (F-NaF) uptake on positron emission tomography with computed tomography (PET-CT) identifies active microcalcification and has been shown to correlate with clinical instability in patients with cardiovascular (CV) disease. Statin therapy promotes coronary macrocalcification over time. Our aim was to investigate rosuvastatin effect on atheroma F-NaF uptake.
View Article and Find Full Text PDFAortic valve microcalcification and cardiovascular risk: an exploratory study using sodium fluoride in high cardiovascular risk patients.
Int J Cardiovasc Imaging
August 2020
Institute of Nuclear Sciences Applied To Health - University of Coimbra, Azinhaga de Santa Comba, 3000-548, Coimbra, Portugal.
18F-sodium fluoride (18F-NaF) has been used to access aortic stenosis in clinical research setting. It is known that its uptake is related with microcalcification. The purpose of this study was to assess the relationship between 18F-NaF uptake by the aortic valve and cardiovascular risk.
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