1 results match your criteria: "Institute of Navy Medicine Research[Affiliation]"
Improved cellular immune response elicited by a ubiquitin-fused ESAT-6 DNA vaccine against Mycobacterium tuberculosis.
Microbiol Immunol
July 2009
The Ship Environmental Health Division, Institute of Navy Medicine Research, Xiangyin Road 880, Shanghai, China.
Article Synopsis
- The study tested a DNA vaccine that combines the ESAT-6 protein with ubiquitin to combat Mycobacterium tuberculosis in mice.
- Mice receiving the ubiquitin-fused vaccine showed a stronger immune response, indicated by increased levels of Th1-type cytokines and T-cell activity.
- The findings suggest that this fusion vaccine enhances immune protection against tuberculosis by improving specific cellular immune responses.