2 results match your criteria: "Institute of Molecular Biology and Biotechnology (I.M.B.B)[Affiliation]"

Application of multispectral imaging detects areas with neuronal myelin loss, without tissue labelling.

Microscopy (Oxf)

April 2016

Department of Pharmacology, School of Medicine, University of Crete, Voutes Campus, Heraklion, Crete GR-71003, Greece Institute of Molecular Biology and Biotechnology (I.M.B.B.), Foundation for Research and Technology, Hellas (FO.R.T.H.), Nikolaou Plastira 100, Vassilika Vouton GR-70013 Heraklion, Crete, Greece.

The application of multispectral imaging to discriminate myelinated and demyelinated areas of neural tissue is herein presented. The method is applied through a custom-made, multispectral imaging monochromator, coupled to a commercially available microscope. In the present work, a series of spinal cord sections were analysed derived from mice with experimental autoimmune encephalomyelitis (EAE), an experimental model widely used to study multiple sclerosis (MS).

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The structures of the reduced (Cu1+) blue-copper protein pseudoazurin from Alcaligenes faecalis strain S-6 are refined at pH 7.8 and 4.4 using X-ray diffraction data to 1.

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