Association between serum 25(OH)D concentrations and bone stress fractures in Finnish young men.

Unlabelled: Low vitamin D level may predict rickets, osteomalacia, or osteoporosis. We examined serum 25(OH)D concentration as a predisposing factor for bone stress fracture in 756 military recruits. The average serum 25(OH)D concentration was significantly lower in the group with fracture, suggesting a relationship between vitamin D and fatigue bone stress fracture.

Development of an ultra rapid and simple multiplex polymerase chain reaction technique for detection of Salmonella typhi.

Objective: To make a rapid and definite diagnosis of Salmonella enteritis, using an ultra rapid multiplex polymerase chain reaction (PCR) detection method for major Salmonella serotypes, such as Salmonella typhi, Salmonella Typhimurium and Salmonella Havana.

Methods: We performed this study at the Research Center of Molecular Biology, Institute of Military Medicine, Bagyatallah University of Medical Sciences, Iran from June 2004 to July 2005. The PCR primers for tyv (rfbE), prt (rfbS) and invA genes were designed and used for the rapid identification of Salmonella enterica serovars Typhi and Paratyphi A with multiplex PCR.

Tissue response to polyglycolide, polydioxanone, polylevolactide, and metallic pins in cancellous bone: An experimental study on rabbits.

The purpose of this study was to investigate, qualitatively and histoquantitatively, the tissue response of rabbit femur cancellous bone to polyglycolide (PGA), polydioxanone (PDS), polylevolactide (PLLA), and stainless steel pins under identical conditions. Eighty knees in 50 rabbits were operated on by inserting bioabsorbable pins (PGA, PDS, or PLLA) together with metallic Kirschner wire in 60, and two metallic Kirschner wires alone in 20 knees, while 20 knees served as intact controls. Follow-up times were 3, 6, 12, 24, and 52 weeks.

Long-term tissue response to bioabsorbable poly-L-lactide and metallic screws: an experimental study.

Late, clinically manifest, adverse inflammatory reactions have sometimes occurred after the use of slowly degrading bioabsorbable poly-l-lactide (PLLA) devices in clinical series of bone fixation. In this study, long-term tissue response to bioabsorbable fracture fixation screws made of poly-l-lactide and to similar metallic screws in cancellous bone was examined and compared with intact bone. The postoperative evaluation of the rabbit femora was performed by using plain radiography, microradiography, histology, histomorphometry, and oxytetracycline labeling studies.

Cancer incidence and causes of death among total hip replacement patients: a review based on Nordic cohorts with a special emphasis on metal-on-metal bearings.

All patients with total hip arthroplasty (THA) are exposed to soluble or particulate forms of Co and Cr. Adverse effects of these wear products are not known. Data from Nordic registries is used to estimate adverse effects on a large scale, based mostly on metal-on-polyethylene bearings.

Severe vascular gunshot injuries of the extremities: a ten-year nation-wide analysis from Finland.

Background And Aims: Gunshot wounds affecting the main vessels of the extremities mostly threaten limb salvage. The purpose of this study was to analyse the nature and severity of civilian vascular gunshot injuries of the extremities using a nation-wide database.

Material And Methods: Retrospective analysis of the Finnish Hospital Discharge Register, hospital records and death certificates over a 10-year period from January 1, 1990 to December 31, 1999.

Fatigue bone injuries causing anterior lower leg pain.

Unlabelled: Shin splints, or stress-related anterior lower leg pain, seem to arise from numerous causes, including stress fractures. We retrospectively reviewed 154 consecutive military patients who had magnetic resonance imaging during a 5-year period for stress-related anterior lower leg pain. Using magnetic resonance imaging, 143 bone stress injuries were diagnosed in 86 of the 154 (56%) patients.

Bone stress injuries of the talus in military recruits.

The purpose of the present study was to assess the incidence, anatomic distribution, and nature of fatigue bone stress injuries of the talus in military recruits based on magnetic resonance imaging (MRI). Military recruits referred to MRI examination due to exercise-induced ankle and/or foot pain were identified from the MRI archives. MR images of cases with bone stress injury findings in the talus were retrospectively re-evaluated concerning the anatomic location and type of the bone stress injury.

[Study on the safety and immunogenicity of enterotoxigenic Escherichia coli recombinant active vaccine].

Objective: To study the safety, immunogenicity on the enterotoxige Escherichia coli (E. coli) recombinant active vaccine FE3 and FE16.

Methods: Toxicity and immunogenicity of the vaccine were determined by experiments on enterotoxigenic E.

The mechanism [correction of mehanism] of spatial [correction of spetial] orientation in conditions of G-stress.

Six test subjects were subjected to lateral (+Gy) and longitudinal-lateral (+Gz/+Gy) accelerations in a centrifuge with a rotation radius of 6.55 m. During rotation, test subjects were instructed to indicate the position of subjective visual vertical.

Fatigue injuries of the femur.

The purpose of this study was to describe the anatomical distribution and incidence of fatigue injuries of the femur in physically-active young adults, based upon MRI studies. During a period of 70 months, 1857 patients with exercise-induced pain in the femur underwent MRI of the pelvis, hips, femora, and/or knees. Of these, 170 patients had a total of 185 fatigue injuries, giving an incidence of 199 per 100 000 person-years.

Bone stress injuries causing exercise-induced knee pain.

Background: No comprehensive studies of bone stress injuries in the knee based on magnetic resonance imaging findings have been published.

Purpose: Assess the incidence, location, nature, and patterns of bone stress injuries in the knee in military conscripts with exercise-induced knee pain.

Study Design: Case series; Level of evidence, 4.

Hospitalisation for injuries among Finnish conscripts in 1990-1999.

Objective: To describe the incidence, trends and nature of hospitalisation for injuries among Finnish conscripts between 1990 and 1999.

Study Design And Setting: A hospital discharge register study on the hospitalisation for injuries with a follow-up of 213509-person-years.

Results: During the 10-year study period, altogether 20016 hospitalisations for injuries were registered.

Leishmaniasis among soldiers of stabilization forces in Iraq. Review article.

The results of studies concerning the incidence of leishmaniasis among soldiers of Stabilization Forces serving in Iraq in the years from 2003 to March 2004 are presented in this article, in the light of a possibility of importation of this disease to the countries of their origin. Epidemiology, clinical picture, laboratory diagnosis, treatment and prevention of leishmaniasis are described. In mid-2004, more than 2400 Polish soldiers served in Iraq.

[Analysis of the E gene sequences of three dengue virus type 1 isolates in Guangdong province].

Objective: To trace the infection sources of three dengue virus type 1 isolates found in Guangdong province, namely GD05/99, GD14/97 and GD23/95.

Methods: According to the genomes of dengue virus type 1 S275 strain, a pair of primers was designed for amplification of the structural protein E gene of the isolated dengue virus type 1 strains by reverse transcriptase-PCR. The amplified gene fragment was then cloned into pMD18-T vector and sequenced.

[Preliminary studies on proliferation of hemorrhagic fever with renal syndrome virus in Leptotrombidium (L.) Scutellare].

In order to observe further the proliferation and kinetic changes of hemorrhagic fever with renal syndrome virus (HFRSV) in Leptotrombidium (L.) Scutellare infected with HFRSV, the raised Leptotrombidium (L.) Scutellare which were at larve stage or at nymph stage were grinded and sterilized by filtration at interval of 20 days, each batch of the filtrate was inoculated separately to Vero-E6 cells and the titre (TCID50/ml) of HFRSV was measured.

Self-medication among Finnish young men in the beginning of common military service.

Purpose: Little is known about self-medication in adolescent and young adult males, particularly in ones exposed to increased stress. The objective of this article is to analyze self-medication and its predictors in young Finnish men at entry into common military service.

Methods: The responding men (n = 857) from nine brigades anonymously completed a self-administered questionnaire during the first conscription days before active military training in July 1999.

Effect of melatonin, ascorbic acid, and succinic acid on the cumulative toxic effect of repeated treatment with gammafos (amifostine).

Daily treatment of outbred albino mice with gammafos in radioprotective doses of 300 and 500 mg/kg for 4 days produced a cumulative toxic effect. This effect was not observed after decreasing the dose of gammafos to 100 mg/kg. Repeated peroral administration of melatonin and ascorbic acid in a dose of 200 mg/kg 30 min before treatment with gammafos reduced its cumulative toxic effect.

[Screening and identification of mimic epitopes of monoclonal antibodies against hantaan virus using phage display technique].

Aim: To obtain mimic epitopes of monoclonal antibody (mAb) against Hantaan virus, and identify preliminarily their immunological characteristics.

Methods: Group-specific mAbs F3 and B11 were used as selective molecules for biopanning. After biopanning, the positive phages were identified by ELISA and DNA sequencing.

[Antioxidant system of the rat brain in toxic lung edema].

The state of enzymatic and nonenzymatic components of antioxidant system and also lipid peroxidation processes were studied in brain of rats with toxic pulmonary edema induced by inhalation of nitric oxides. The changes in the state of antioxidant system components in brain accompanied the development of toxic pulmonary edema. The main changes were found in nonenzymatic components of the antioxidant system, particularly in thiol and disulfide groups.

[Comparative effectiveness of antioxidant melatonin and radioprotectors indralin and phenylephrine in local radiation injuries].

In experiments on mice radioprotective properties of indraline, phenyleprine and melatonin were compared at topical application as an ointment at a place of local exposure of animal hind to a dose of 38.3 Gy of 60Co gamma-quanta. Factor of dose reduction was 1.

The influence of ambulation time on the incidence of transient neurologic symptoms after lidocaine spinal anesthesia.

Unlabelled: The cause of transient neurologic symptoms (TNSs) after lidocaine spinal anesthesia remains unclear. It has been proposed that early ambulation after spinal anesthesia contributes to the development of TNSs. We evaluated the influence of ambulation time on the occurrence of TNSs after spinal anesthesia with 50 mg of 2% plain lidocaine for knee arthroscopy.