Systematic review of parenteral ketamine for managing acute agitation in emergency settings.

Introduction: Agitation, a significant psychiatric issue often linked to conditions like schizophrenia, bipolar disorder, and major depression, invariably pose challenges in emergency settings. Acute agitation occurs in 2.6 % of emergency cases and up to 12.

Care provider's experiences on working with homeless persons with mental illness in institutions: A qualitative study.

Introduction: Homelessness embodies a prevalent societal issue that results in extensive socio-economic ramifications. Residential rehabilitation establishments, including shelters and mental health facilities, offer essential assistance to individuals with insecure housing situations. The healthcare providers within these facilities struggle to effectively tackle the underlying issues faced by homeless individuals, often due to a variety of socio-economic factors.

Effectiveness of psychosocial intervention and functionality among homeless persons with mental illness.

Background: Homelessness is a deeply ingrained aspect of our culture. It has a detrimental influence on people of all ages' physical and mental well-being, child development, academic success and the establishment and upkeep of families. Homelessness and mental illness have a reciprocal relationship that makes them two interrelated social issues that affect people's ability to function and communities all over the world.

Characterization of neuronal oscillations in the prelimbic cortex, nucleus accumbens and CA1 hippocampus during object retrieval task in rats predisposed to early life stress.

Background: Early life stress (ELS) during the stress hypo-responsive period (SHRP) alters the curiosity-like behavior later during adolescence. Previous studies have shown maternal separation (MS) stress-induced heightened curiosity and associated risk-taking behavior in the object retrieval task (ORT). However, the neural correlates of curiosity in adolescent rats predisposed to early life stress remain unexplored.

Damaged Relay Station: EEG Neurofeedback Training in Isolated Bilateral Paramedian Thalamic Infarct.

Stroke is a major public health concern and leads to significant disability. Bilateral thalamic infarcts are rare and can result in severe and chronic cognitive and behavioral disturbances-apathy, personality change, executive dysfunctions, and anterograde amnesia. There is a paucity of literature on neuropsychological rehabilitation in patients with bilateral thalamic infarcts.

Genetic spectrum of neuronal ceroid lipofuscinosis & its genotype-phenotype correlation -A single centre experience of 56 cases.

Background: Neuronal ceroid lipofuscinoses (NCLs) are progressive, autosomal recessive lysosomal storage disorders primarily affecting children, marked by seizures, cognitive decline, motor regression, and visual impairment. Limited genetic data exist for South Asian populations, with most studies relying on enzymatic assays or electron microscopy. This study explores the genetic spectrum of NCL and genotype-phenotype correlations in a cohort from South India.

Diagnosing missed cases of spinal muscular atrophy in genome, exome, and panel sequencing datasets.

Purpose: We set out to develop a publicly available tool that could accurately diagnose spinal muscular atrophy (SMA) in exome, genome or panel sequencing datasets aligned to a GRCh37, GRCh38, or T2T reference genome.

Methods: The SMA Finder algorithm detects the most common genetic causes of SMA by evaluating reads that overlap the c.840 position of the SMN1 and SMN2 paralogs.

A qualitative study to explore the experiences faced by primary caregivers of children with mental illness during the COVID-19 pandemic at the child and adolescent psychiatry OPD.

Aim: To explore the lived-in experiences of primary caregivers of children with mental illness while taking care during the coronavirus disease 2019 (COVID-19) pandemic.

Methodology: This study is a descriptive phenomenological study. Convenience sampling was used.

Novel Presentation of Type 1 Wolfram Syndrome as Intracranial Hemorrhage and Longitudinally Extensive Transverse Myelitis: Neuroimaging and Angiographic Findings.

Wolfram syndrome (WS), a rare genetic neurodegenerative condition, is primarily characterized by diabetes mellitus, optic atrophy, diabetes insipidus, and sensorineural hearing loss, along with diverse systemic manifestations. Late-stage cases exhibit widespread brain atrophy. While bleeding tendencies are not commonly observed in Type 2 WS (WS2), there is a distinctive bleeding tendency that is exclusive to WS2, with no documented occurrences in Type 1 WS (WS1).

Does psychoeducation module-based community intervention address Internet addiction among school-going adolescents? A quasi-experimental study from Mangalore, India.

Unlabelled: Excessive and uncontrolled use of the Internet leads to Internet addiction and negatively affects the physical and mental health of adolescents. Normalization of the Internet and electronic gadgets during the COVID-19 pandemic increased the vulnerability of adolescents to developing behavioral dependency on Internet use. Intervention is needed to protect the formative years and to grow as responsible net users.

Prediction of H3K27M alteration in midline gliomas of the brain using radiomics: A multi-institute study.

Background: Noninvasive prediction of H3K27M-altered Diffuse midline gliomas is important because of the involvement of deep locations and proximity to eloquent structures. We aim to predict H3K27M alteration in midline gliomas using radiomics features of T2W images.

Methods: Radiomics features extracted from 124 subjects (69 H3K27M-altered/55 H3K27M-wild type).

Acute effects of fast, slow, and graded Suryanamaskar on cardiorespiratory and cardiac autonomic functions.

Background: Suryanamaskar (SN) is a popular yogic practice due to its health benefits and fitness promises. This study aims to assess the acute effects of different paces of SN on cardiorespiratory responses and heart rate variability (HRV).

Methods: In this self-as-control comparative study, seventeen male yoga practitioners performed three rounds of SN at fast (FSN), slow (SSN), and graded (GSN) pace in a randomly allocated sequence.

Anticoagulation Status and Outcome in Cerebral Venous Thrombosis: A Single-Center Retrospective Study from South India.

Background And Objectives: Early initiation and maintenance of anticoagulation appears to be the mainstay of treatment of cerebral venous thrombosis (CVT), but the evidence supporting the intensity and duration of anticoagulation is limited.

Methods: We retrospectively collected data of patients admitted with CVT over a 5-year period, who had a minimum of 6 months of clinical follow-up and three or more prothrombin time international normalized ratio (INR) values spread over 6 months. Data collected included demographic, clinical, and radiologic parameters, anticoagulation status during the follow-up, complications, and clinical status at the last follow-up.

Assessing alcohol industry penetration and government safeguards: the International Alcohol Control Study.

Background: The alcohol industry uses many of the tobacco industry's strategies to influence policy-making, yet unlike the Framework Convention on Tobacco Control, there is no intergovernmental guidance on protecting policies from alcohol industry influence. Systematic assessment of alcohol industry penetration and government safeguards is also lacking. Here, we aimed to identify the nature and extent of industry penetration in a cross-section of jurisdictions.

Mental Health Issues and Psychosocial Contexts in CICL Children Versus Non-CICL Children: A Comparative Study.

Background: Children in conflict with law (CICL) is an emerging issue in the contemporary world. Children between the ages of 12 years and 18 years are the most productive age group, but some children may develop behaviors that are undesirable to society by violating laws. The mental health and associated psychosocial factors of such children are lacking in India.

Barriers to Seek Professional Help for Mental Health Scale: Development and Psychometric Validation.

Background: Mental health conditions are highly prevalent, and both supply- and demand-side factors drive a high treatment gap. There is a dearth of socio-culturally appropriate measures to assess barriers to professional help-seeking in distressed non-treatment seekers. This study aimed to develop and validate the Barriers to Seek Professional Help for Mental Health Scale for distressed, non-treatment-seeking young adults experiencing common mental health concerns in the Indian context.

Treatment Needs of Patients With Severe Alcohol Use Disorders.

Background: People with alcohol use disorders (AUDs) have varied needs while they seek treatment. Understanding and focusing on the needs will improve treatment outcomes. The objective of the study is to qualitatively assess the treatment-related needs of patients with AUDs admitted to a tertiary care treatment center.

Pregnant Women Presenting to Psychiatric Emergency Services: A Retrospective Chart Review from India.

Background: Managing psychiatric emergencies during pregnancy is often challenging, as the safety of both the mother and the unborn fetus needs to be considered. This study aimed to examine the nature of psychiatric emergencies in pregnancy, their management, and clinical outcomes in women presenting to a psychiatry emergency room (ER).

Methods: Charts of perinatal women consulting psychiatry ER between January 2016 and June 2021 were reviewed for the nature of the psychiatric emergency, pregnancy details, psychiatric symptoms, sociodemographic information, medical comorbidities, clinical diagnosis, and care plan.

The Prevalence and Correlates of Internet Addiction in India as Assessed by Young's Internet Addiction Test: A Systematic Review and Meta-analysis.

Background: Earlier research on internet addiction (IA) in the adult population in India has concentrated on isolated prevalence surveys conducted nationwide. A systematic grasp of pooled prevalence necessitates a meta-level evaluation of all prior literature. This study aims to investigate the prevalence of IA and its correlates among adults in India.