644 results match your criteria: "Institute of Medical Information[Affiliation]"
BMC Cancer
January 2025
Institute of Medical Information, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Background: Identifying high risk factors and predicting lung cancer incidence risk are essential to prevention and intervention of lung cancer for the elderly. We aim to develop lung cancer incidence risk prediction model in the elderly to facilitate early intervention and prevention of lung cancer.
Methods: We stratified the population into six subgroups according to age and gender.
Hum Vaccin Immunother
December 2025
Institute of Medical Information & Library, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
mRNA vaccines offer groundbreaking technological advantages and broad application potential. Their rapid advancement, particularly during the COVID-19 pandemic, is the result of decades of research and numerous technological breakthroughs. These discoveries build upon each other, forming dense, interconnected networks of progress.
View Article and Find Full Text PDFPatient Prefer Adherence
January 2025
School of Health Policy and Management, Peking Union Medical College, Beijing, People's Republic of China.
Objective: Population aging and epidemiological transition have prompted requests for integrating health and social care. The goal of meeting complex care needs necessitates the understanding of preferred patterns among older adults. The study aimed to elicit the preferred care patterns and the influencing factors of integrated health and social care among community-dwelling older adults in multiple regions of China.
View Article and Find Full Text PDFChin Med Sci J
December 2024
Institute of Medical Information, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100020, China.
In recent years, with the policy reform of new drug review and approval, China has ushered in a surge of innovative drug development. Based on the Pharnexcloud database and the Pharmcube database, we analyzed the innovative drugs approved for marketing and entered clinical trials in China, sorted out the major research and development (R&D) institutions and enterprises, the distribution of innovative drug target types, and the primary therapeutic areas of the approved innovative drugs, and compared with the global innovative drug R&D landscape. Since 2020, China's innovative drug development has shown a rapid growth trend, with intense competition among biopharmaceutical companies, and the emergence of a number of leading biopharmaceutical enterprises.
View Article and Find Full Text PDFHum Resour Health
January 2025
Health Development Research Department, Capital Institute of Pediatrics, Beijing, 100020, People's Republic of China.
Background: Quantitative methods for estimating the workload of primary healthcare (PHC) workers are essential for improving the performance of PHC institutions. However, measuring the workload of PHC workers is challenging due to the diverse and complex range of services covered by PHC. This study aims to use an equivalent value (EV)-based approach to assess the workload of PHC workers and inform policymakers about the current workload burden in Beijing, China.
View Article and Find Full Text PDFEur J Nucl Med Mol Imaging
January 2025
Huashan Hospital and Human Phenome Institute, Fudan University, 220 Handan Road, Shanghai, 200433, China.
Objective: This study aims to conduct a bibliometric analysis to explore research trends, collaboration patterns, and emerging themes in the PET/MR field based on published literature from 2010 to 2024.
Methods: A detailed literature search was performed using the Web of Science Core Collection (WoSCC) database with keywords related to PET/MR. A total of 4,349 publications were retrieved and analyzed using various bibliometric tools, including VOSviewer and CiteSpace.
Brief Bioinform
November 2024
Institute of Medical Information, Chinese Academy of Medical Sciences and Peking Union Medical College, Chaoyang District, Beijing 100020, China.
Drug resistance in Mycobacterium tuberculosis (Mtb) is a significant challenge in the control and treatment of tuberculosis, making efforts to combat the spread of this global health burden more difficult. To accelerate anti-tuberculosis drug discovery, repurposing clinically approved or investigational drugs for the treatment of tuberculosis by computational methods has become an attractive strategy. In this study, we developed a virtual screening workflow that combines multiple machine learning and deep learning models, and 11 576 compounds extracted from the DrugBank database were screened against Mtb.
View Article and Find Full Text PDFBMC Public Health
December 2024
Department of Hospital Group Office, Shenzhen Luohu Hospital Group Luohu People's Hospital, Shenzhen, 518001, China.
Background: The Chinese government has introduced a series of hierarchical medical policies to ensure continuity of care, but referrals remain difficult to implement effectively. This study aimed to evaluate the chronic disease referral network and explore the problems associated with the specific implementation of referrals.
Methods: This study was a repeated cross-sectional study of monthly data collected between August 2017 and December 2023 in Luohu district, Shenzhen, China.
Med Care
November 2024
Institute of Clinical Biometrics, Center for Medical Data Science, Medical University of Vienna, Vienna, Austria.
Background: Practice guidelines recommend patient management based on scientific evidence. Quality indicators gauge adherence to such recommendations and assess health care quality. They are usually defined as adverse event rates, which may not fully capture guideline adherence over time.
View Article and Find Full Text PDFExploration (Beijing)
December 2024
Department of Occupational and Environmental Health and the Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, School of Public Health Fourth Military Medical University Xi'an China.
Alzheimer's disease (AD) is a debilitating systemic disorder that has a detrimental impact on the overall well-being of individuals. Emerging research suggests that long non-coding RNAs play a role in neural development and function. Nevertheless, the precise relationship between lncRNAs and Alzheimer's disease remains uncertain.
View Article and Find Full Text PDFFront Psychiatry
November 2024
Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China.
Background: Anxiety disorders are among the most prevalent mental health conditions globally, particularly affecting adolescents and young adults (10-24 years), and causing substantial psychological and social impairments. This study analyzed changes in the incidence, prevalence, and disability-adjusted life years (DALYs) of anxiety disorders in this age group from 1990 to 2021, emphasizing the impact of socioeconomic disparities and the COVID-19 pandemic, particularly post-2019.
Methods: Utilizing the Global Burden of Disease(GBD) 2021 data from 204 countries, this study evaluated global trends in anxiety disorders among adolescents and young adults.
Database (Oxford)
December 2024
Intelligent Computing Department, Institute of Medical Information & Library, Chinese Academy of Medical Sciences/Peking Union Medical College, No. 3 Yabao Road, Beijing 100020, China.
Atherosclerotic cerebrovascular disease could result in a great number of deaths and disabilities. However, it did not acquire enough attention. Less information, statistics, or data on the disease has been revealed.
View Article and Find Full Text PDFPeerJ Comput Sci
June 2024
Institute of Medical Information, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China.
Background: To make the question text represent more information and construct an end-to-end text clustering model, we propose a double-target self-supervised clustering with multi-feature fusion (MF-DSC) for texts which describe questions related to the medical field. Since medical question-and-answer data are unstructured texts and characterized by short characters and irregular language use, the features extracted by a single model cannot fully characterize the text content.
Methods: Firstly, word weights were obtained based on term frequency, and word vectors were generated according to lexical semantic information.
PeerJ Comput Sci
October 2024
Department of Biomedical Engineering, University of Malaya, Kuala Lumpur, Malaysia.
With the increasing availability of diverse healthcare data sources, such as medical images and electronic health records, there is a growing need to effectively integrate and fuse this multimodal data for comprehensive analysis and decision-making. However, despite its potential, multimodal data fusion in healthcare remains limited. This review paper provides an overview of existing literature on multimodal data fusion in healthcare, covering 69 relevant works published between 2018 and 2024.
View Article and Find Full Text PDFFront Pharmacol
November 2024
Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China.
Objectives: This study aimed to identify the risk factors for pancreatic cancer through machine learning.
Methods: We investigated the relationships between different risk factors and pancreatic cancer using a real-world retrospective cohort study conducted at West China Hospital of Sichuan University. Multivariable logistic regression, with pancreatic cancer as the outcome, was used to identify covariates associated with pancreatic cancer.
Health Res Policy Syst
December 2024
London School of Hygiene and Tropical Medicine, European Observatory On Health Systems and Policies, London, UK.
Background: In response to climate change-induced increases in heat periods, the WHO recommends the implementation of heat health action plans (HHAPs). In Germany, HHAPs are implemented neither comprehensively nor nationwide. Several recommendations have identified the public health service (PHS) at municipal and federal state levels as a key actor regarding to heat and health.
View Article and Find Full Text PDFFront Med
November 2024
Institute of Medical Information/Medical Library, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100020, China.
Environ Health Perspect
November 2024
Department of Environmental and Occupational Health, Joe C. Wen School of Population & Public Health, University of California, Irvine, California, USA.
Background: Postpartum depression (PPD) has been associated with biological, emotional, social, and environmental factors. However, evidence regarding the effect of temperature on PPD is extremely limited.
Objectives: We aimed to examine the associations between postpartum temperature exposure and PPD.
BMJ Surg Interv Health Technol
November 2024
School of Public Health, Peking University, Beijing, China.
Gastric cancer (GC) remains a significant global health challenge, with high mortality rates, particularly in low- and middle-income countries, like China. Early detection through screening is crucial for improving prognosis and reducing mortality. However, uptake of GC screening remains suboptimal, highlighting the need for effective interventions to promote screening participation.
View Article and Find Full Text PDFComput Biol Med
January 2025
Institute of Medical Information, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS&PUMC), Beijing, 100020, China. Electronic address:
JAMA Netw Open
November 2024
Radiology Department, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.
Importance: Understanding the association of artificial intelligence (AI) with physician burnout is crucial for fostering a collaborative interactive environment between physicians and AI.
Objective: To estimate the association between AI use in radiology and radiologist burnout.
Design, Setting, And Participants: This cross-sectional study conducted a questionnaire survey between May and October 2023, using the national quality control system of radiology in China.
J Inflamm Res
November 2024
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Aim: The interaction between inflammatory biomarkers (high-sensitivity C-reactive protein, hsCRP) and antioxidants (uric acid, UA) regarding prognosis after ischemic stroke or transient ischemic attack (TIA) remains inadequately explored. This study aimed to assess (1) the individual and joint effects of hsCRP and UA, and (2) the neuroprotective role of UA in patients with elevated hsCRP levels concerning poor functional outcomes at 90 days.
Methods: A prospective cohort study was conducted involving 2140 consecutive ischemic stroke or TIA patients with hsCRP and UA levels.
JMIR Form Res
November 2024
Institute of Medical Information and Library, Chinese Academy of Medical Sciences/Peking Union Medical College, Beijing, China.
Background: Nutrient needs vary over the lifespan. Improving knowledge of both population groups and care providers can help with healthier food choices, thereby promoting population health and preventing diseases. Providing evidence-based food knowledge online is credible, low cost, and easily accessible.
View Article and Find Full Text PDFMol Ecol Resour
November 2024
Department of Computer Science and Technology, Tsinghua University, Beijing, China.
Symbiotic microbiota strongly impact host physiology. Amphibians and reptiles occupy a pivotal role in the evolutionary history of Animalia, and they are of significant ecological, economic, and scientific value. Many prior studies have found that symbiotic microbiota in herpetofaunal species are closely associated with host phylogeny, physiological traits, and environmental factors; however, insufficient integrated databases hinder researchers from querying, accessing, and reanalyzing these resources.
View Article and Find Full Text PDFAlcohol Alcohol
September 2024
Centre for Digital Transformation, School of Computing and Information Technology, Faculty of Engineering and Information Sciences, University of Wollongong, Northfields Ave Wollongong, New South Wales 2522, Australia.
Background: Process mining was widely used in healthcare settings to analyse patient pathways, providing insights about patient care and resource allocation. This study aimed to apply process mining to explore service utilization and pathways of patients with alcohol use disorders in receiving the community-based Drug and Alcohol Service to establish a baseline for evaluating improvement initiatives.
Methods: Patients' encounters with the Drug and Alcohol Service and their direct care activities (i.