318 results match your criteria: "Institute of Mathematics and Computer Science[Affiliation]"

Purpose: Deep learning-based radiomics techniques have the potential to aid specialists and physicians in performing decision-making in COVID-19 scenarios. Specifically, a Deep Learning (DL) ensemble model is employed to classify medical images when addressing the diagnosis during the classification tasks for COVID-19 using chest X-ray images. It also provides feasible and reliable visual explicability concerning the results to support decision-making.

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Measures to curb the spread of SARS-CoV-2 impacted not only COVID-19 dynamics, but also other infectious diseases, such as dengue in Brazil. The COVID-19 pandemic disrupted not only transmission dynamics due to changes in mobility patterns, but also several aspects of surveillance, such as care seeking behavior and clinical capacity. However, we lack a clear understanding of the overall impact on dengue in different parts of Brazil and the contribution of individual causal drivers.

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We derive exact equations for the spectral density of sparse networks with an arbitrary distribution of the number of single edges and triangles per node. These equations enable a systematic investigation of the effects of clustering on the spectral properties of the network adjacency matrix. In the case of heterogeneous networks, we demonstrate that the spectral density becomes more symmetric as the fluctuations in the triangle-degree sequence increase.

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Background: Tuberculosis (TB) remains one of the top infectious killers in the world and a prominent fatal disease in developing countries. This study proposes a prototypical solution to early prevention of TB based on its primary symptoms, signs, and risk factors, implemented by means of machine learning (ML) predictive algorithms. Further novelty of the study lies in the uniqueness of patient dataset collected from three top-ranked hospitals of Sindh, Pakistan, a self-administered survey patient-records that comprises a set of questions asked by the doctors treating TB patients in real-time.

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Tiberius: end-to-end deep learning with an HMM for gene prediction.

Bioinformatics

November 2024

Institute of Mathematics and Computer Science, University of Greifswald, Greifswald 17489, Germany.

Motivation: For more than 25 years, learning-based eukaryotic gene predictors were driven by hidden Markov models (HMMs), which were directly inputted a DNA sequence. Recently, Holst et al. demonstrated with their program Helixer that the accuracy of ab initio eukaryotic gene prediction can be improved by combining deep learning layers with a separate HMM postprocessor.

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Random walks find extensive applications across various complex network domains, including embedding generation and link prediction. Despite the widespread utilization of random walks, the precise impact of distinct biases on embedding generation from sequence data and their subsequent effects on link prediction remain elusive. We conduct a comparative analysis of several random walk strategies, including the true self-avoiding random walk and the traditional random walk.

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Article Synopsis
  • A fungal pathogen affecting low-input apple production has become more widespread in Europe over the past 15 years, yet little is known about its biology and ability to cause disease.
  • This study focused on strain DC1_JKI from Germany, which was sequenced to achieve a comprehensive genome assembly, revealing a mating-type locus identified as MAT1-2.
  • Analysis across European and Asian samples showed that only MAT1-2 was present in European samples, potentially explaining the absence of the sexual reproduction form of the pathogen in European apple orchards.
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Article Synopsis
  • Type 2 diabetes (T2D) genome-wide association studies (GWASs) typically miss rare genetic variants due to limitations in previous imputation methods and insufficient whole-genome sequencing data.
  • In a large-scale study involving over half a million individuals, researchers uncovered 12 new genetic variants linked to T2D, including a rare enhancer variant near the LEP gene that significantly increases risk.
  • The study also analyzed ClinVar variants related to monogenic diabetes, identifying additional rare variants that affect T2D risk and offering new insights into the pathogenicity of certain variants previously deemed uncertain.
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Background: Noncommunicable diseases (NCDs) predominantly affect adults, but pathophysiological changes begin decades earlier, as a continuum, with initial events apparent in adolescence. Hence, early identification and intervention are crucial for the prevention and management of NCDs. We investigated the complex network of socioeconomic, behavioral, and metabolic factors associated with the presence of NCD in Brazilian adolescents.

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The Josefson-Nissenzweig theorem and filters on .

Arch Math Log

April 2024

Department of Mathematics, Kurt Gödel Research Center, Vienna University, Vienna, Austria.

For a free filter on , endow the space , where , with the topology in which every element of is isolated whereas all open neighborhoods of are of the form for . Spaces of the form constitute the class of the simplest non-discrete Tychonoff spaces. The aim of this paper is to study them in the context of the celebrated Josefson-Nissenzweig theorem from Banach space theory.

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learnMSA2: deep protein multiple alignments with large language and hidden Markov models.

Bioinformatics

September 2024

Institute of Mathematics and Computer Science, University of Greifswald, 17489 Greifswald, Germany.

Motivation: For the alignment of large numbers of protein sequences, tools are predominant that decide to align two residues using only simple prior knowledge, e.g. amino acid substitution matrices, and using only part of the available data.

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Cascade Proportional-Integral Control Design and Affordable Instrumentation System for Enhanced Performance of Electrolytic Dry Cells.

Sensors (Basel)

August 2024

Programa de Pós-Graduação em Instrumentação, Controle e Automação de Processos de Mineração, Universidade Federal de Ouro Preto (UFOP), Ouro Preto 35402-163, MG, Brazil.

In this paper, we present a cost-effective system for monitoring and controlling alkaline electrolyzers, intending to improve hydrogen gas production on a laboratory scale. Our work includes two main innovations. Firstly, we suggest an approach to calibrate a standard air flow meter to accurately measure the flow of hydrogen-rich gas from electrolyzers, improving measurement accuracy while keeping costs low.

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A technique for preserving network structure in randomized Hi-C data.

J Bioinform Comput Biol

October 2024

Institute of Mathematics and Computer Science, University of Latvia, Rainis Boulevard 29, Riga LV-1459, Latvia.

Chromatin interaction data are frequently analyzed as a network to study several aspects of chromatin structure. Hi-C experiments are costly and there is a need to create simulated networks for quality assessment or result validation purposes. Existing tools do not maintain network properties during randomization.

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Characterizing behavioural differentiation in gene regulatory networks with representation graphs.

NAR Genom Bioinform

September 2024

Institute of Mathematics and Computer Science, University of Latvia, Raina bulvaris 29, Riga LV1459, Latvia.

We introduce the formal notion of representation graphs, encapsulating the state space structure of gene regulatory network models in a compact and concise form that highlights the most significant features of stable states and differentiation processes leading to distinct stability regions. The concept has been developed in the context of a hybrid system-based gene network modelling framework; however, we anticipate that it can also be adapted to other approaches of modelling gene networks in discrete terms. We describe a practical algorithm for representation graph computation as well as two case studies demonstrating their real-world application and utility.

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Gene prediction has remained an active area of bioinformatics research for a long time. Still, gene prediction in large eukaryotic genomes presents a challenge that must be addressed by new algorithms. The amount and significance of the evidence available from transcriptomes and proteomes vary across genomes, between genes, and even along a single gene.

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This study aims to analyze deforestation in the Brazilian Amazon from 1999 to 2020 using machine learning techniques to assess 16 critical factors. Our approach leverages the capabilities of machine learning, particularly Random Forest, which proved to be the most accurate model in terms of determination coefficient, mean squared error, and mean absolute error. The analysis revealed that the harvested area of permanent crops is the most influential variable in predicting deforestation, followed by the area of temporary crops.

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Background: The purpose of this systematic review (SR) is to gather evidence on the use of machine learning (ML) models in the diagnosis of intraosseous lesions in gnathic bones and to analyze the reliability, impact, and usefulness of such models. This SR was performed in accordance with the PRISMA 2022 guidelines and was registered in the PROSPERO database (CRD42022379298).

Methods: The acronym PICOS was used to structure the inquiry-focused review question "Is Artificial Intelligence reliable for the diagnosis of intraosseous lesions in gnathic bones?" The literature search was conducted in various electronic databases, including PubMed, Embase, Scopus, Cochrane Library, Web of Science, Lilacs, IEEE Xplore, and Gray Literature (Google Scholar and ProQuest).

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Automated Detection and Counting of Wild Boar in Camera Trap Images.

Animals (Basel)

May 2024

Institute of Epidemiology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Südufer 10, 17493 Greifswald-Insel Riems, Germany.

Camera traps are becoming widely used for wildlife monitoring and management. However, manual analysis of the resulting image sets is labor-intensive, time-consuming and costly. This study shows that automated computer vision techniques can be extremely helpful in this regard, as they can rapidly and automatically extract valuable information from the images.

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Uncertainties and discrepant results in identifying crucial areas for emotional facial expression recognition may stem from the eye tracking data analysis methods used. Many studies employ parameters of analysis that predominantly prioritize the examination of the foveal vision angle, ignoring the potential influences of simultaneous parafoveal and peripheral information. To explore the possible underlying causes of these discrepancies, we investigated the role of the visual field aperture in emotional facial expression recognition with 163 volunteers randomly assigned to three groups: no visual restriction (NVR), parafoveal and foveal vision (PFFV), and foveal vision (FV).

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Artistic pieces can be studied from several perspectives, one example being their reception among readers over time. In the present work, we approach this interesting topic from the standpoint of literary works, particularly assessing the task of predicting whether a book will become a best seller. Unlike previous approaches, we focused on the full content of books and considered visualization and classification tasks.

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Autonomous driving navigation relies on diverse approaches, each with advantages and limitations depending on various factors. For HD maps, modular systems excel, while end-to-end methods dominate mapless scenarios. However, few leverage the strengths of both.

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Tinnitus is a conscious attended awareness perception of sourceless sound. Widespread theoretical and evidence-based neurofunctional and psychological models have tried to explain tinnitus-related distress considering the influence of psychological and cognitive factors. However, tinnitus models seem to be less focused on causality, thereby easily misleading interpretations.

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