Polarized Tunneling Transistor for Ultralow-Energy-Consumption Artificial Synapse toward Neuromorphic Computing.

Neural networks based on low-power artificial synapses can significantly reduce energy consumption, which is of great importance in today's era of artificial intelligence. Two-dimensional (2D) material-based floating-gate transistors (FGTs) have emerged as compelling candidates for simulating artificial synapses owing to their multilevel and nonvolatile data storage capabilities. However, the low erasing/programming speed of FGTs renders them unsuitable for low-energy-consumption artificial synapses, thereby limiting their potential in high-energy-efficient neuromorphic computing.

Phylogenetic diversity of functional genes in deep-sea cold seeps: a novel perspective on metagenomics.

Background: Leakages of cold, methane-rich fluids from subsurface reservoirs to the sea floor are termed cold seeps. Recent exploration of the deep sea has shed new light on the microbial communities in cold seeps. However, conventional metagenomic methods largely rely on reference databases and neglect the phylogeny of functional genes.

Discordant patterns between nitrogen-cycling functional traits and taxa in distant coastal sediments reveal important community assembly mechanisms.

A central question in microbial ecology is how immense microbes are assembled in changing natural environments while executing critical ecosystem functions. Over the past decade, effort has been made to unravel the contribution of stochasticity and determinism to the compositional of microbial communities. However, most studies focus on microbial taxa, ignoring the importance of functional traits.

Survival of surface bacteriophages and their hosts in deep-sea environments.

The survival of the sinking prokaryotes and viruses in the deep-sea environment is crucial for deep-sea ecosystems and biogeochemical cycles. Through an deep-sea long-term incubation device, our results showed that viral particles and infectivity had still not decayed completely after incubation for 1 year. This suggests that, via infection and lysis, surface viruses with long-term infectious activity deep-sea environments may influence deep-sea microbial populations in terms of activity, function, diversity, and community structure and ultimately affect deep-sea biogeochemical cycles, highlighting the need for additional research in this area.

A novel long-tailed myovirus represents a new T4-like cyanophage cluster.

Cyanophages affect the abundance, diversity, metabolism, and evolution of picocyanobacteria in marine ecosystems. Here we report an estuarine phage, S-CREM2, which represents a novel viral genus and leads to the establishment of a new T4-like cyanophage clade named cluster C. S-CREM2 possesses the longest tail (~418 nm) among isolated cyanomyoviruses and encodes six tail-related proteins that are exclusively homologous to those predicted in the cluster C cyanophages.

A novel and efficient electrochemiluminescence sensing strategy for the determination of trimethylamine oxide in seafood.

A novel and efficient electrochemiluminescence (ECL) sensing strategy and a solid-state ECL sensor was proposed to detect trimethylamine oxide (TMAO), which is widely presented in marine species and has important physiological functions. TMAO was reduced by Fe(II)-EDTA complex to trimethylamine, acting as coreactant, to amplify the ECL response of the Ru (bpy) system. To improve the detection sensitivity and efficiency, a robust solid-state ECL probe was prepared and a flow injection ECL detection system was established with a specially designed flow ECL unit, under the excitation of stepping pulse potentials.

Variations in copepod composition and diversity in relation to eutrophication and hydrology in İzmir Bay, Aegean Sea.

Hyrographic and trophic gradient along Izmir Bay used to assess their effects on the copepod composition and diversity. Trophic state of the bay varied from oligotrophic in the outer region to hypertrophic condition in the inner region as stated by trophic index (TRIX). Aegean Sea water entrance and trophic conditions of the bay affected species assemblages.

Numerical study of critical straight, frown, and chevron incisions in small incision cataract surgery.

When an intraocular lens (IOL) injector is inserted through a pre-cut corneal incision (e.g., an empirical size of 2.

PZT-Enabled MoS Floating Gate Transistors: Overcoming Boltzmann Tyranny and Achieving Ultralow Energy Consumption for High-Accuracy Neuromorphic Computing.

Low-power electronic devices play a pivotal role in the burgeoning artificial intelligence era. The study of such devices encompasses low-subthreshold swing (SS) transistors and neuromorphic devices. However, conventional field-effect transistors (FETs) face the inherent limitation of the "Boltzmann tyranny", which restricts SS to 60 mV decade at room temperature.

Global diversity and biogeography of DNA viral communities in activated sludge systems.

Background: Activated sludge (AS) systems in wastewater treatment plants (WWTPs) harbor enormous viruses that regulate microbial metabolism and nutrient cycling, significantly influencing the stability of AS systems. However, our knowledge about the diversity of viral taxonomic groups and functional traits in global AS systems is still limited. To address this gap, we investigated the global diversity and biogeography of DNA viral communities in AS systems using 85,114 viral operational taxonomic units (vOTUs) recovered from 144 AS samples collected across 54 WWTPs from 13 different countries.

Selective RNA Processing and Stabilization are Multi-Layer and Stoichiometric Regulators of Gene Expression in Escherichia coli.

Selective RNA processing and stabilization (SRPS) facilitates the differential expression of multiple genes in polycistronic operons. However, how the coordinated actions of SRPS-related enzymes affect stoichiometric regulation remains unclear. In the present study, the first genome-wide targetome analysis is reported of these enzymes in Escherichia coli, at a single-nucleotide resolution.

Microfluidic Platforms for Real-Time In Situ Monitoring of Biomarkers for Cellular Processes.

Cellular processes are mechanisms carried out at the cellular level that are aimed at guaranteeing the stability of the organism they comprise. The investigation of cellular processes is key to understanding cell fate, understanding pathogenic mechanisms, and developing new therapeutic technologies. Microfluidic platforms are thought to be the most powerful tools among all methodologies for investigating cellular processes because they can integrate almost all types of the existing intracellular and extracellular biomarker-sensing methods and observation approaches for cell behavior, combined with precisely controlled cell culture, manipulation, stimulation, and analysis.

Feeding Behavior Responses of the Small Copepod, , to Toxic Algae at Different Concentrations.

The feeding relationship between copepods and phytoplankton has immense ecological significance. This study investigated the feeding behavior of copepods by studying the feeding selectivity of , a key small copepod species, using a high-speed camera. The feeding behavior of separately fed on three algae, , and , was studied at five different concentrations.

GDPF: a data resource for the distribution of prokaryotic protein families across the global biosphere.

Microorganisms encode most of the functions of life on Earth. However, conventional research has primarily focused on specific environments such as humans, soil and oceans, leaving the distribution of functional families throughout the global biosphere poorly comprehended. Here, we present the database of the global distribution of prokaryotic protein families (GDPF, http://bioinfo.

Nutrient dynamics in the Bohai and North Yellow seas from seasonal to decadal scales: Unveiling Bohai Sea eutrophication mitigation in the 2010s.

The eutrophication status in the central Bohai Sea tends to be mitigated in recent years. To explore the recent nutrient status, seasonal surveys were carried out from 2018 to 2021, covering both the Bohai Sea and the adjacent North Yellow Sea. In recent cold seasons, both dissolved inorganic nitrogen concentration (DIN) and the ratio of DIN to soluble reactive phosphorus were lower than those in 2016.

Effect of ocean warming on pigment and photosynthetic carbon fixation of plankton assemblage in Pingtan Island of Southeast China.

Temperature plays an important role in affecting the physiological traits of marine plankton. In this study, we conducted an outdoor incubation experiment to investigate the effects of elevated temperature on Chl a, photosynthetic carbon fixation and the composition of plankton communities in the surface seawater around Pingtan Island, the northwest Taiwan Strait in Autumn 2022. After 3-4 days of incubation, elevated temperature (1-4 °C higher than ambient temperature) led to a decrease in Chl a concentration across all three stations, did not result in significant increases in the particulate organic carbon (POC) and nitrogen (PON) concentrations in seawater with high nitrate concentrations, whereas increased POC and PON concentrations in nitrate-limited seawater.

Effects of exposure to nanoplastics on the gill of mussels Mytilus galloprovincialis: An integrated perspective from multiple biomarkers.

The pervasive presence of nanoplastics (NPs) in marine environments poses a threat to marine organisms. Gills, as the organ in direct contact with the environment in marine invertebrates, maybe the first to accumulate NPs. To date, the toxic effects of NPs on the gills of marine invertebrates are still largely unknown.

Hydrogel platform facilitating astrocytic differentiation through cell mechanosensing and YAP-mediated transcription.

Astrocytes are multifunctional glial cells that are essential for brain functioning. Most existing methods to induce astrocytes from stem cells are inefficient, requiring couples of weeks. Here, we designed an alginate hydrogel-based method to realize high-efficiency astrocytic differentiation from human neural stem cells.

Monthly-scale hydro-climatic forecasting and climate change impact evaluation based on a novel DCNN-Transformer network.

Climate change has emerged as one of the foremost global challenges confronting humanity today, leading to a heightened frequency and intensity of extreme weather phenomena, including droughts, floods, and erratic rainfall patterns. Accurately predicting changes in runoff patterns under future climate conditions holds significant importance for effective regional water resource planning and management. Recent research on runoff forecast has centered on optimizing hyperparameters of ELM, RNN, LSTM models using PSO, GWO, SSA, and other algorithms.

Extensive intragenomic variation in the internal transcribed spacer region of fungi.

Fungi are among the most biodiverse organisms in the world. Accurate species identification is imperative for studies on fungal ecology and evolution. The internal transcribed spacer (ITS) rDNA region has been widely accepted as the universal barcode for fungi.

Mitigation of EH36 ship steel biocorrosion using an antimicrobial peptide as a green biocide enhancer.

In this study, a 13-mer antimicrobial peptide (RRWRIVVIRVRRC) named by E6 was used as an enhancer of a green biocide to mitigate the biocorrosion of EH36 ship steel. Results show that a low concentration of E6 (100 nM) alone was no-biocidal and could not resist the Desulfovibrio vulgaris adhesion on the EH36 steel surface. However, E6 enhanced the bactericidal effect of tetrakis hydroxymethyl phosphonium sulfate (THPS).

Relationship between cell volume and particulate organic matter for different size phytoplankton.

Phytoplankton biomass is an intuitive indicator to evaluate the stability of marine ecosystems. How to obtain phytoplankton biomass quickly and accurately is the focus of marine research. In this work, we selected 12 phytoplankton species to explore the relationship between cell volume and cellular compounds.

EVMP: enhancing machine learning models for synthetic promoter strength prediction by Extended Vision Mutant Priority framework.

Introduction: In metabolic engineering and synthetic biology applications, promoters with appropriate strengths are critical. However, it is time-consuming and laborious to annotate promoter strength by experiments. Nowadays, constructing mutation-based synthetic promoter libraries that span multiple orders of magnitude of promoter strength is receiving increasing attention.