Community member attitudes and understanding of "serious mental illness": A mixed-method study.

Objective: "Serious mental illness" (SMI) is a priority population within mental health treatment and policy. However, there is no standard operational definition across research, clinical, and policy contexts. The use of the label has also not been evaluated regarding its association with stigma among the general public.

Lip print evidence: Poland as the Last Bastion of Practical Cheiloscopy.

Cheiloscopic examinations have long been conducted, and many scientists have reported the usefulness of cheiloscopy for personal identification with a characteristic and individual pattern of furrows on the vermilion lip. For almost 40 years, research conducted in Poland has determined the patterns of these furrows and the separation and development of their individual features. This was the basis for forming expert opinions and presenting them in court as evidence.

[Health and safety challenges in medical entities and the powers of the social labor inspector: Lessons related to the COVID-19 outbreak in the context of internal control of employee health and safety].

Employees in the medical profession in a situation where the life of a patient is at risk cannot refrain from working due to unsafe working conditions. Therefore, enforcing the right to safe and hygienic working conditions is particularly important so that employees can provide health care services without additional burdens. The purpose of the study is to determine how the social labour inspector can respond to Occupational Health and Safety (OHS) hazards and whether the current powers of the social labor inspectorate as the employer's internal OHS control body are sufficient.

Approval and therapeutic value of gene therapies in the US and Europe.

Gene therapies are a fast-growing area of innovation and hold promise for the treatment of many diseases currently with unmet medical need. To better understand the clinical importance of the current landscape of approved gene therapies, we conducted a systematic analysis of the approved gene therapies and their added therapeutic value. Through December 2022, 13 gene therapies have been approved in the US, 15 in the EU, and 9 in Switzerland.

Regulatory Review Duration and Differences in Submission Times of Drugs in the United States and Europe, 2011 to 2020.

The speed of drug regulatory agencies in the United States and Europe is often a source of discussion. The objective of this research was to assess regulatory review duration of first and supplementary indications approved between 2011 and 2020 in the United States and Europe (European Union [EU] and Switzerland) and differences in submission times between the United States and Europe. Descriptive statistics were applied to review times between the jurisdictions and across the therapeutic areas.

The prevalence of traumatic brain injury (TBI) among people impacted by the criminal legal system: An updated meta-analysis and subgroup analyses.

Objective: Traumatic brain injury (TBI) is a significant public health concern and has implications for people directly impacted by the criminal legal system during arrest, conviction, incarceration, and community supervision. This meta-analysis estimated the lifetime prevalence of TBI among people supervised by the criminal legal system across settings.

Hypotheses: Building on previous research, we hypothesized that prevalence estimates would be impacted by methodological, clinical, and demographic factors.

The status of work-related COVID-19 prevention measures and risk factors in hospitals.

Background: Health care workers (HCWs) in hospitals are at risk of infection with coronavirus disease 2019 (COVID-19). Prevention measures are necessary to protect HCWs against COVID-19.

Objective: This study aimed to determine the status of occupational risk factors and prevention measures for COVID-19 in hospitals.

Understanding the challenges of disaster victim identification: perspectives of Australian forensic practitioners.

Disaster victim identification (DVI) is an important process in the aftermath of disasters to provide answers for the families and communities of victims. Australian forensic practitioners contribute to such processes internationally under difficult post-disaster circumstances. The aim of the study was to better understand the challenges experienced by forensic practitioners in international DVI operations.

Levels of Essential and Trace Elements in Mozzarella Available on the Slovak Market with the Estimation of Consumer Exposure.

The aim of this study was to determinate the content of some elements in a specific dairy product, mozzarella, in a particular area of western Slovakia and to evaluate the estimation of the risk to the consumers based on the contribution to the provisional tolerable weekly intake. The consumption of mozzarella can contribute to the intake of important elements in the diet, such as calcium and magnesium, along with others. The contents of some toxic and trace elements were low and have not exceeded the permitted limit.

The cancer premium - explaining differences in prices for cancer vs non-cancer drugs with efficacy and epidemiological endpoints in the US, Germany, and Switzerland: a cross sectional study.

Background: High treatment prices of new cancer drugs are a global public health challenge to patients and healthcare systems. Policymakers in the US and Europe are debating reforms to drug pricing. The objective of this study was to assess whether drug efficacy or epidemiological characteristics (prevalence, incidence, mortality) explain the gap in treatment prices between cancer and non-cancer drugs in the US, Germany, and Switzerland.

Therapeutic value of first versus supplemental indications of drugs in US and Europe (2011-20): retrospective cohort study.

Objective: To analyze the therapeutic value of supplemental indications compared with first indications for drugs approved in the US and Europe.

Design: Retrospective cohort study.

Setting: New and supplemental indications approved by the US Food and Drug Administration (FDA) and European Medicines Agency (EMA) between 2011 and 2020.

STATE REGISTRY OF HUMAN GENOMIC INFORMATION IN UKRAINE: HOW TO ACHIEVE A BALANCE BETWEEN LAW, MEDICINE AND ETHICS.

Objective: The aim: The purpose of this study is to analyze the provisions of the Law of Ukraine "On State Registration of Human Genomic Information" and to make proposals for its improvement taking into account international experience.

Patients And Methods: Materials and methods: The study was conducted on the basis of the analysis of normative material, investigative and judicial practice, decisions of the ECtHR, the position of experts involved in the process of identification of deceased persons, which was expressed during the Second All-Ukrainian Forum of Forensic Experts on June 17, 2022, and a working meeting of the leadership of the KNDISE, DSU "Main Bureau of Forensic Medical Examination of the Ministry of Health of Ukraine" with a representative of the European Training Center for Identification of Victims of Natural Disasters and Forensic Examination in Central Europe (ETAF) (Germany).

Conclusion: Conclusions: The Law of Ukraine «On the State Register of Human Genomic Information» is a progressive step towards normalizing the use of DNA analysis as an evidence tool.

Clinical Trial Data Transparency in the EU: Is the New Clinical Trials Regulation a Game-Changer?

The benefits of access to clinical trial data are related to their inestimable value from the perspective of clinical trial participants, society as a whole, public health systems and scientific progress. In light of the development of innovative data analysis technologies, access to raw clinical trial data opens up an ever-widening array of possibilities: it can profoundly facilitate machine data analysis for, , hypothesis generation, risk modelling, counterfactual simulation and - finally - drug repurposing and development. The enactment of the new Clinical Trials Regulation (EU) No.

Anticipation or resilience in times of emergent crisis? COVID-19 responses in the United States, Taiwan, and South Korea.

This research employs Wildavsky's two -strategies-anticipation and resilience-as our conceptual framework to compare COVID-19 policies in the United States, South Korea, and Taiwan. Also, following Handmer and Dovers' three types of resilience, we develop theory-driven codes and then explain how governmental structures and cultural factors influenced governmental responses. We found that a key response to this pandemic is arguably correlated with how quick and flexible a government can adopt different types of resilient strategies.

Has the Russian invasion of Ukraine reinforced anti-globalization sentiment in Austria?

Unlabelled: The Russian invasion of Ukraine has caused disruptions in international trade and highlighted the dependency of small open economies in Europe on imports, especially of energy. These events may have changed Europeans' attitude towards globalization. We study two waves of representative population surveys conducted in Austria, one right before the Russian invasion and the other two months later.

Regulation of GMO field trials in the EU and new genomic techniques: will the planned reform facilitate experimenting with gene-edited plants?

This study presents the possible consequences of maintaining the current regulatory regime of the experimental release of genetically modified higher plants in the EU for the products of new genomic techniques (NGTs). Currently, the experimental release is a crucial stage before the authorization of a product for the market. By analyzing the data on the performance of field trials in the EU (numbers, sizes, dominating countries) and comparing the present regulatory provisions with those of selected third countries (including new provisions adopted in the UK), this study shows that the current framework of GMO (genetically modified organisms) field trials is ill-fitted for breeding activities.

Determinants of cancer drug pricing and how to overcome the cancer premium.

The high and increasing prices of cancer drugs are a public health challenge. To disrupt the cancer premium and improve patient access to cancer drugs, different action steps are indicated: more transparency on the price determination process and actual prices, value-based pricing, and "price with evidence development."

Evaluations of competence to stand trial are evolving amid a national "competency crisis".

Across the United States, court orders for competence to stand trial (CST) evaluations and competence restoration services have been increasing much more rapidly than states can provide these services, prompting what has been called a national "competency crisis." The challenge in providing timely competence restoration services has, in several jurisdictions, prompted a change in competence evaluations. Evaluators are more often required to address broader clinical issues-such as recommending placement or addressing the urgency of hospitalization-rather than addressing only CST.

The approaching pilot for One Health governance index.

Background: One Health approach advocates realizing the best health and harmonious symbiosis of human, animal and natural environment through cross-border, multi-sectoral and interdisciplinary cooperation. The good governance model is the leading factor for the performance of One Health governance. In order to tackle the complex problems in the One Health governance at the global level, the variation of One Health governance in different countries was analyzed by a set of indicators within the One Health system.

Doping in Sport-Attitudes of Physical Trainers Students Regarding the Use of Prohibited Substances Increasing Performance.

Background: The popularity of using the advice of a personal trainer is increasing in Poland and currently most gyms offer the possibility of training under the supervision of a professional. Personal trainers present a multifaceted nature into physical activity and become their clients' guides in achieving sporting goals. Physical trainers also work in sports clubs and supervise the training of people professionally involved in sport.

Perceptions of blind proficiency testing among latent print examiners.

In recent years, scholars have levied multiple criticisms against traditional proficiency testing procedures in forensic laboratories. Consequently, on several occasions, authorities have formally recommended that laboratories implement blind proficiency testing procedures. Implementation has been slow, but laboratory management has increasingly expressed interest in initiating blind testing in at least some forensic disciplines, with some laboratories conducting blind testing in almost all disciplines.