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Background And Objectives: An increased prevalence of herpes simplex virus type 2 (HSV-2) infection has been recently observed in industrialized countries.

Goal: To determine HSV-2 seroprevalence in a high-risk population in Italy.

Study Design: A cross-sectional study was performed to ascertain the HSV-2 prevalence among 919 persons attending an STD clinic in northern Italy.

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