1 results match your criteria: "Institute of Hematology and Blood Disases Hospital[Affiliation]"
[Cytogenetic and clinical study on 126 cases of B cell non-Hodgkin's lymphoma with bone marrow involvement].
Zhonghua Xue Ye Xue Za Zhi
January 2011
Institute of Hematology and Blood Disases Hospital, CAMS and PUMC, Tianjin 300020, China.
Article Synopsis
- The study analyzed the cytogenetic features of 126 patients with B cell non-Hodgkin's lymphoma (B-NHL) involving bone marrow to determine clinical significance and prognostic factors.
- Among the findings, diffuse large B-cell lymphoma (DLBCL) was the most prevalent type, and chromosome abnormalities were observed in 41.3% of patients, indicating a higher likelihood of these abnormalities in aggressive forms of lymphoma compared to indolent types.
- The presence of certain chromosomal aberrations correlated with shorter overall survival in DLBCL and mantle cell lymphoma (MCL), suggesting that specific genetic changes can inform prognosis.