162 results match your criteria: "Institute of Health Sciences Research [IUNICS- IdISBa][Affiliation]"

Background: Metabolic age is defined as an estimation of a person's age based on their basal metabolic rate (BMR) and other physiological health indicators. Unlike chronological age, which simply measures the number of years lived since birth, metabolic age is based on various health and fitness markers that estimate the body's "true" biological age and can be assessed using various methodologies, including bioimpedance. The aim of this study was to evaluate how age, sex, social class, smoking habits, physical activity, and adherence to the Mediterranean diet influence metabolic age.

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Study Objectives: To use a nationally representative sample to (1) evaluate the factor structure of the patient-reported outcome measurement information system (PROMIS) parent proxy pediatric sleep scales (Spanish translation), (2) examine the invariance of these scales across sex and across different developmental periods of childhood and adolescence, (3) confirm the information and precision of the scales using item response theory (IRT), and (4) provide age-based normative information.

Methods: Parents of a nationally representative sample of 5525 Spanish children and adolescents ages 5-16 years (56.1% boys) completed the Spanish translation parent proxy short versions of the sleep disturbance and sleep-related impairment scales.

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Phytate Effects on Incomplete Distal Renal Tubular Acidosis.

J Clin Med

August 2024

Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research (IUNICS), University of Balearic Islands, 07122 Palma de Mallorca, Spain.

Adults who have incomplete distal renal tubular acidosis (dRTA) may present with recurrent urolithiasis due to metabolic acidosis, leading to bone resorption, which in turn causes hypercalciuria and urine alkalinization (pH > 6.0). Oral potassium citrate is the most commonly used treatment for dRTA, but some patients cannot tolerate this treatment.

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Article Synopsis
  • The CALCIPHYX trial tested hexasodium fytate, a potential treatment for calciphylaxis, a rare condition causing painful skin lesions, in a double-blind, placebo-controlled setting.
  • Out of the randomised patients, both those receiving hexasodium fytate and the placebo group showed similar improvements in wound assessment and pain scores after 12 weeks, indicating no significant benefit from the treatment over placebo.
  • Serious adverse events were lower in the fytate group compared to the placebo group, suggesting that hexasodium fytate may be safer, but there was no substantial difference in healing or pain reduction between the two groups.
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In this work, we proposed a sensitive and selective colorimetric assay for single nucleotide mutation (SNM) detection combining rolling circle amplification (RCA) and G-quadruplex/hemin DNAzyme complex formation. In the detection principle, the first step involves ssDNA hybridization with a padlock probe (PLP) DNA, which can discriminate a single base mismatch. The successful ligation is followed by an RCA event to generate an abundance of G-quadruplexes (GQ-RCA) which are then transformed into a DNAzyme (G-quadruplex/hemin complex) by the addition of hemin.

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  • Experts met to discuss the best ways to treat urinary stones at a conference in Spain in January 2024.
  • For 1.5 cm kidney stones, two treatments called m-PCNL and RIRS work well, but m-PCNL is cheaper and quicker, while RIRS has fewer side effects.
  • Doctors need to be careful with patients on certain medications, as some treatments might cause more bleeding, and they should also make sure to test for infections before and after surgery.
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Validity and Reproducibility of an Electronic Food Frequency Questionnaire in Argentinian Adults.

Nutrients

May 2024

Interdisciplinary Center for Research in Health and Behavioral Sciences, School of Medicine and Health Sciences, Universidad Adventista del Plata, Libertador San Martín 3103, Argentina.

This study aimed to validate a semiquantitative electronic food frequency questionnaire (eFFQ) in estimating the intake of a comprehensive list of nutrients and bioactive compounds among adults from six regions of Argentina using multiple 24 h dietary recall (24HR) as a reference. A total of 163 adults completed two administrations of the eFFQ and four 24HRs. The paired -test/Wilcoxon signed-rank test, Spearman/Pearson correlations, cross-classification, weighted kappa statistics, and Bland-Altman plots were employed to determine relative validity.

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Cystine Renal Calculi: New Aspects Related to Their Formation and Development.

J Clin Med

May 2024

Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research (IUNICS-IdISBa), University of Balearic Islands, 07122 Palma de Mallorca, Spain.

: Crystallization experiments of renal-calculi-forming compounds (calcium oxalate, calcium phosphates, uric acid) are normally performed by monitoring these processes during periods of time similar to the residence of urine inside the kidney. Nevertheless, cystine requires high supersaturation for its crystallization, and most experiments last for longer periods. It must be considered that at high supersaturation, the inhibitors of crystalline development have poor effects.

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Background: This study sought to determine whether cognitive disengagement syndrome (CDS, formerly sluggish cognitive tempo) has different external correlates relative to ADHD-inattentive presentation (INP), ADHD-hyperactive/impulsive presentation (HIP), and ADHD-combined presentation (CP).

Methods: Parents of a nationally representative sample of 5,525 Spanish youth (ages: 5-16, 56.1% boys) completed measures of CDS, ADHD-inattention (IN), and ADHD-hyperactivity/impulsivity (HI) and other measures.

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Global outbreaks of foodborne hepatitis A: Systematic review and meta-analysis.

Heliyon

April 2024

South Asia Infant Feeding Research Network (SAIFRN), Division of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Institute of Higher Education, Wardha, India.

Hepatitis A Virus (HAV) is a significant threat in terms of food safety. A systematic literature search with the research question "What are the clinical outcomes of foodborne Hepatitis A virus infections?" was conducted. The pooled estimate of the outcomes-mortality, hospitalization, and severity rates, along with a 95% confidence interval (CI), was estimated.

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The effect of social pension on health-related quality of life of the rural older people: a panel study from China.

BMC Geriatr

March 2024

School of International Studies, Renmin University of China, 59 Zhongguancun Street, Haidian District, Beijing, China.

Background: Social pensions, social assistance systems for older people in rural areas, have been put into place in many nations and have positively impacted health. The long-term health consequences of social pension programs in China are uncertain. The aim of this study is to evaluate the long-term health consequences of the new rural social pension (NRSP) for the rural older people in China.

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Despite WHO recommendations to reduce the global prevalence of anemia among women of reproductive age by 2025, anemia remains a truly global public health problem, especially among pregnant women. The objective of our study was to examine the relationship between anemia and the place of residence in pregnant women. This cross-sectional study was conducted in six health facilities between December 2018 and March 2019.

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Article Synopsis
  • A study was conducted in India to investigate sudden unexplained deaths among healthy young adults (ages 18-45) possibly linked to COVID-19 infection or vaccination from October 2021 to March 2023.
  • The research analyzed data from 729 cases and 2,916 matching controls, assessing factors like COVID-19 vaccination status, family history, substance use, and physical activity.
  • Results indicated that receiving at least one COVID-19 vaccine dose reduced the likelihood of sudden death, while factors such as past hospitalization for COVID-19, family history of sudden deaths, binge drinking, and intense physical activity increased the risk.
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Introduction: Previous studies have used different individual scales to examine the relationship of depression with emotional intelligence, empathy, and immune-based diseases. In this study, we used a combination of psychometric scales to examine the relationships of depression with emotional intelligence (intrapersonal and interpersonal), empathy (affective and cognitive), and symptoms of weakened immune system.

Methods: This cross-sectional prospective study examined 158 volunteers (39 males and 119 females).

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Sexual harassment in universities harms the physical and psychological health and development of students. Although Chinese universities are required to implement sexual harassment interventions, few studies have estimated how well interventions are perceived by students and the association with their perceptions and attitudes toward sexual harassment. This study aims to examine the perceptions and attitudes toward sexual harassment and perceived sexual harassment interventions among university students.

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(1) Background: This study aimed to determine the relationship between metabolic urine conditions and the formation, severity, and composition of encrustations in ureteral stents. (2) Methods: Ninety stone-former patients requiring a double-J stent were prospectively enrolled. We collected 24 h metabolic urine samples and demographic data, including indwelling time and previous stone composition.

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Effect of Phytate (InsP6) and Other Inositol-Phosphates (InsP5, InsP4, InsP3, InsP2) on Crystallization of Calcium Oxalate, Brushite, and Hydroxyapatite.

Biomolecules

June 2023

Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research (IUNICS-IdISBa), University of Balearic Islands, 07122 Palma de Mallorca, Spain.

Pathological calcifications may consist of calcium oxalate (CaOx), hydroxyapatite (HAP), and brushite (BRU). The objective of this study was to evaluate the effect of phytate (inositol hexakisphosphate, InsP6), InsP6 hydrolysates, and individual lower InsPs (InsP5, InsP4, InsP3, and InsP2) on the crystallization of CaOx, HAP and BRU in artificial urine. All of the lower InsPs seem to inhibit the crystallization of calcium salts in biological fluids, although our in vitro results showed that InsP6 and InsP5 were stronger inhibitors of CaOx crystallization, and InsP5 and InsP4 were stronger inhibitors of BRU crystallization.

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Children with cerebral palsy (CP) present motor learning disorders and somatosensory dysfunction. Although many protocols use videogames in children with CP, few apply or examine motor learning principles. This study aims at (1) implementing therapist-user-designer collaboration in adapting a videogame to the principles of motor learning and the characteristics of users with CP, and (2) piloting the effectiveness of these adaptations by analyzing the achievement of motor learning parameters (learning rate acquisition, retention, and transfer to motor and somatosensory function).

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Efficacy of Theobromine and Its Metabolites in Reducing the Risk of Uric Acid Lithiasis.

Int J Mol Sci

June 2023

Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research (IUNICS-IdISBa), University of Balearic Islands, 07122 Palma de Mallorca, Spain.

Uric acid lithiasis accounts for about 10% of all types of renal lithiasis. The most common causes of uric acid lithiasis are low urinary pH, followed by high concentration of urinary uric acid, and low diuresis. Treatment of patients consists of alkalinization of urine, reducing the consumption of purine-rich foods, and administration of xanthine oxidase inhibitors, because there are no established therapeutic inhibitors of uric acid crystallization.

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Daily phytate intake increases adiponectin levels among patients with diabetes type 2: a randomized crossover trial.

Nutr Diabetes

February 2023

Vascular and Metabolic Diseases Research Group, Endocrinology Department, Son Llàtzer University Hospital, Institute of Health Sciences Research [IdISBa], 07198, Palma of Mallorca, Spain.

Aim: Adiponectin, a major adipokine secreted by adipose tissue, has been shown to improve insulin sensitivity. Myo-inositol hexaphosphate (phytate; InsP6) is a natural compound that is abundant in cereals, legumes, and nuts that has demonstrated to have different beneficial properties in patients with diabetes type 2.

Methods: We performed a randomized crossover trial to investigate the impact of daily consumption of InsP6 on serum levels of adiponectin, TNF-alpha, IL-6, and IL-1beta in patients with type 2 diabetes mellitus (T2DM; n = 39).

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Factors Affecting the Use of Pain-Coping Strategies in Individuals with Cerebral Palsy and Individuals with Typical Development.

Children (Basel)

January 2023

University Institute of Health Sciences Research (IUNICS-IdISBa), University of the Balearic Islands, 07122 Palma de Mallorca, Spain.

Many individuals with cerebral palsy (CP) suffer from pain and must develop pain-coping strategies, although the factors determining them are unknown. This observational study aims at exploring the association between different pain-coping strategies and factors such as age, sex, pain, health status, sleep or motor and cognitive function in individuals with cerebral palsy (CP) and typically developing peers (TD). Main caregivers of 94 individuals with CP (age range = 6-69 years, mean age = 17.

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Confounding factors leading to misdiagnosing ventricular tachycardia as supraventricular in the emergency room.

Indian Pacing Electrophysiol J

December 2022

Arrhythmia and Electrophysiology Department, Biocor Instituto, Rede Dor São Luis, Nova Lima, Minas Gerais, Brazil. Electronic address:

Studies conducted during the last 50 years have proposed electrocardiographic criteria and algorithms to determine if a wide QRS tachycardia is ventricular or supraventricular in origin. Sustained ventricular tachycardia is an uncommon reason for consultation in the emergency room. The latter and the complexity of available electrocardiographic diagnostic criteria and algorithms result in frequent misdiagnoses.

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Phytate Dephosphorylation Products Also Act as Potent Inhibitors of Calcium Oxalate Crystallization.

Molecules

August 2022

Laboratory of Renal Lithiasis Research, University Institute of Health Sciences Research (IUNICS-IdISBa), University of Balearic Islands, 07122 Palma de Mallorca, Spain.

Phytate has been classified as an anti-nutrient, but there are no adverse effects from the consumption of a balanced diet with 1 to 2 g of daily phytate (inositol-hexaphosphate, InsP6) as a calcium magnesium salt, the form naturally present in grains. Furthermore, recent research has shown that phytate consumption may prevent pathological calcifications, such as kidney stones and cardiovascular calcifications. However, many endogenous and exogenous enzymes can hydrolyze phytate to lower inositol phosphates (InsPs) that also have biological activity.

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