4 results match your criteria: "Institute of Frontier and Interdisciplinary Science. Shandong University[Affiliation]"

Dual-Responsive hollow mesoporous organosilicon nanocarriers for photodynamic therapy.

J Colloid Interface Sci

April 2024

Institute of Molecular Sciences and Engineering, Institute of Frontier and Interdisciplinary Science. Shandong University, Qingdao, Shandong 266237, PR China. Electronic address:

Hypothesis: The nano-delivery platform, -SS-HMONs@MB@MnO nanoparticles (SMM NPs) loaded with methylene blue (MB) as photosensitizer have excellent photodynamic therapy (PDT) effect. The disulfide bond and MnO give the shell redox-responsive properties. SMM NPs consume glutathione (GSH) in tumor cells, reducing the scavenging of reactive oxygen species (ROS) by GSH and enhancing the PDT effect of MB.

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Article Synopsis
  • Silver nanoparticles coated with organic-inorganic or inorganic silica possess antimicrobial properties while enhancing dispersion and stability, with a slow release of silver ions boosting their effectiveness.
  • Two types of silver nanoparticles, Ag@mSiO and Ag@YSiO, were created and tested for their morphology, surface properties, and antimicrobial effects against fungi A. niger and P. citrinum.
  • Ag@mSiO demonstrated superior antimicrobial activity due to greater silver ion release and maintained the quality of silk without altering its color or strength, making it highly suitable for application on silk cultural relics.
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Developing a small molecular photosensitizer to achieve multimodal phototherapy has recently garnered attention as a promising strategy for efficient cancer treatment. However, synthesis of a multifunctional small molecular photosensitizer has remained challenging. Here we report an aggregation-induced-emission (AIE)-featured luminogen (AIEgen) TPA-BTZ decorated with long and branched alkyl chains.

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Porphyrin-based metal coordination polymers (MCPs) have attracted significant attention due to their great promise for applications in phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT). However, the detailed self-assembly process of porphyrin-based MCPs is still poorly understood. This work provides a detailed study of the self-assembly process of MCPs constructed from Mn and TCPP (TCPP: 5,10,15,20-tetrakis(4'-carboxyphenyl)porphyrin) in aqueous solution.

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