2,353 results match your criteria: "Institute of Experimental Physics[Affiliation]"

On the equivocal nature of the mass absorption curves.

Int J Pharm

November 2023

Institute of Experimental Physics, Faculty of Mathematics, Physics and Informatics, University of Gdańsk, Wita Stwosza 57, 80-308 Gdańsk, Poland. Electronic address:

The idea behind the research presented is based upon apparently contradictory experimental results obtained here by means of photoacoustics modalities for the same drug donor/acceptor membrane system, serving as a surrogate for a transdermal delivery system. The first modality allowed for the monitoring of the total amount of mass uptake (m(t)-type data), while the second technique allowed for the quantification of time-dependent concentration distribution within the acceptor membrane (c(x,t)-type data). Despite of a very good agreement between the mt data and the 1st-order uptake fitting model (standard Fickian diffusion with constant source boundary condition), the standard approach failed during the c(x,t) data analysis.

View Article and Find Full Text PDF

Th-containing superconducting high entropy system with the nominal composition (NbTa)[Formula: see text](MoWTh)[Formula: see text] was synthesized. Its structural and physical properties were investigated by X-ray diffraction, scanning electron microscopy, energy dispersive X-ray spectroscopy, specific heat, resistivity and magnetic measurements. Two main phases of alloy were observed: major bcc structure and minor fcc.

View Article and Find Full Text PDF

Variants of garnet-type LiLaZrO are being intensively studied as separator materials in solid-state battery research. The material-specific transport properties, such as bulk and grain boundary conductivity, are of prime interest and are mostly investigated by impedance spectroscopy. Data evaluation is usually based on the one-dimensional (1D) brick layer model, which assumes a homogeneous microstructure of identical grains.

View Article and Find Full Text PDF

The most precise measurements to date of the _{Λ}^{3}H lifetime τ and Λ separation energy B_{Λ} are obtained using the data sample of Pb-Pb collisions at sqrt[s_{NN}]=5.02  TeV collected by ALICE at the LHC. The _{Λ}^{3}H is reconstructed via its charged two-body mesonic decay channel (_{Λ}^{3}H→^{3}He+π^{-} and the charge-conjugate process).

View Article and Find Full Text PDF

We present the first direct search for exotic Higgs boson decays H→AA, A→γγ in events with two photonlike objects. The hypothetical particle A is a low-mass spin-0 particle decaying promptly to a merged diphoton reconstructed as a single photonlike object. We analyze the data collected by the CMS experiment at sqrt[s]=13  TeV corresponding to an integrated luminosity of 136  fb^{-1}.

View Article and Find Full Text PDF

Noise-resistant phase imaging with intensity correlation.

Sci Adv

September 2023

Institute of Experimental Physics, Faculty of Physics, University of Warsaw, ul. Pasteura 5, 02-093 Warszawa, Poland.

Interferometric methods form the basis of highly sensitive measurement techniques from astronomy to bioimaging. Interferometry typically requires high stability between the measured and reference beams. The presence of rapid phase fluctuations washes out interference fringes, making phase profile recovery impossible.

View Article and Find Full Text PDF

The first observation of the production of W^{±}W^{±} bosons from double parton scattering processes using same-sign electron-muon and dimuon events in proton-proton collisions is reported. The data sample corresponds to an integrated luminosity of 138  fb^{-1} recorded at a center-of-mass energy of 13 TeV using the CMS detector at the CERN LHC. Multivariate discriminants are used to distinguish the signal process from the main backgrounds.

View Article and Find Full Text PDF

A search for the rare η→μ^{+}μ^{-}μ^{+}μ^{-} double-Dalitz decay is performed using a sample of proton-proton collisions, collected by the CMS experiment at the CERN LHC with high-rate muon triggers during 2017 and 2018 and corresponding to an integrated luminosity of 101  fb^{-1}. A signal having a statistical significance well in excess of 5 standard deviations is observed. Using the η→μ^{+}μ^{-} decay as normalization, the branching fraction B(η→μ^{+}μ^{-}μ^{+}μ^{-})=[5.

View Article and Find Full Text PDF

The structural and physical properties of the new titanium- and niobium-rich type-A high-entropy alloy (HEA) superconductor Nb0.34Ti0.33Zr0.

View Article and Find Full Text PDF

Wettability, Adsorption and Adhesion in Polymer (PMMA)-Commercially Available Mouthrinse System.

Materials (Basel)

August 2023

Institute of Experimental Physics, Faculty of Mathematics, Physics and Informatics, University of Gdańsk, Wita Stwosza 57, 80-308 Gdańsk, Poland.

The study concerns the evaluation of the physicochemical and thermo-adsorptive surface properties of six commercially available mouthrinses, particularly surface tension, surface activity, partitioning coefficient, critical micellar concentration, Gibbs excesses at interfaces, surface entropy, and enthalpy. The aim was to quantify their effect on the adhesion and wettability of a model poly(methyl methacrylate) (PMMA) polymer. The adsorptive and thermal surface characteristics were derived from surface tension () vs.

View Article and Find Full Text PDF

Given the widespread demand for novel antibacterial agents, we modified a cell-penetrating peptide (KFF)K to transform it into an antibacterial peptide. Namely, we inserted a hydrocarbon staple into the (KFF)K sequence to induce and stabilize its membrane-active secondary structure. The staples were introduced at two positions, (KFF)K[5-9] and (KFF)K[2-6], to retain the initial amphipathic character of the unstapled peptide.

View Article and Find Full Text PDF

Jet quenching is the process of color-charged partons losing energy via interactions with quark-gluon plasma droplets created in heavy-ion collisions. The collective expansion of such droplets is well described by viscous hydrodynamics. Similar evidence of collectivity is consistently observed in smaller collision systems, including pp and p+Pb collisions.

View Article and Find Full Text PDF
Article Synopsis
  • Scientists are exploring mRNA as a new class of drugs, particularly for vaccine technology, due to its rapid production and cost-effectiveness.
  • The small cap structure at the 5' end of mRNA is key for protection and efficient use in protein synthesis, enabling various modifications that enhance mRNA activity.
  • Particularly, N2-modified cap analogues demonstrate promising biological properties and translational activity, suggesting potential future applications in cancer treatment and RNA engineering.
View Article and Find Full Text PDF

Multicellular organization is a requirement for the development of complex organisms, and filamentous cyanobacteria such as represent a paradigmatic case of bacterial multicellularity. The filament can include hundreds of communicated cells that exchange nutrients and regulators and, depending on environmental conditions, can include different cell types specialized in distinct biological functions. Hence, the specific features of the filament and how they are propagated during cell division represent outstanding biological issues.

View Article and Find Full Text PDF

Highly reflective mirrors are indispensable components in a variety of state-of-the-art photonic devices. Typically used, bulky, multi-layered distributed Bragg (DBR) reflectors are limited to lattice-matched semiconductors or nonconductive dielectrics. Here, we introduce an inverted refractive index-contrast grating (ICG) as compact, single-layer alternative to DBR.

View Article and Find Full Text PDF

Aurophilic Molecules on Surfaces. Part I. (NapNC)AuCl on Au(110).

ACS Omega

August 2023

Institute of Experimental Physics, Surface Science Division, Johannes Kepler University, Altenberger Straße 69, 4040 Linz, Austria.

Aurophilicity is a well-known phenomenon in structural gold chemistry and is found in many crystals of Au(I) complexes. However, these attractive dispersion forces between and within complexes containing Au(I) moieties have not been well studied in ultrathin films. In this paper, we elucidate the interaction of chlorido(2-naphthyl isonitrile)gold(I) on and with Au(110) surfaces.

View Article and Find Full Text PDF

A search for the standard model Higgs boson decaying to a charm quark-antiquark pair, H→cc[over ¯], produced in association with a leptonically decaying V (W or Z) boson is presented. The search is performed with proton-proton collisions at sqrt[s]=13  TeV collected by the CMS experiment, corresponding to an integrated luminosity of 138  fb^{-1}. Novel charm jet identification and analysis methods using machine learning techniques are employed.

View Article and Find Full Text PDF

A test of CP invariance in Higgs boson production via vector-boson fusion has been performed in the H→γγ channel using 139  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV collected by the ATLAS detector at the LHC. The optimal observable method is used to probe the CP structure of interactions between the Higgs boson and electroweak gauge bosons, as described by an effective field theory. No sign of CP violation is observed in the data.

View Article and Find Full Text PDF

A search for a long-lived, heavy neutral lepton (N) in 139  fb^{-1} of sqrt[s]=13  TeV pp collision data collected by the ATLAS detector at the Large Hadron Collider is reported. The N is produced via W→Nμ or W→Ne and decays into two charged leptons and a neutrino, forming a displaced vertex. The N mass is used to discriminate between signal and background.

View Article and Find Full Text PDF

Multijet events at large transverse momentum () are measured at using data recorded with the CMS detector at the LHC, corresponding to an integrated luminosity of . The multiplicity of jets with that are produced in association with a high- dijet system is measured in various ranges of the of the jet with the highest transverse momentum and as a function of the azimuthal angle difference between the two highest jets in the dijet system. The differential production cross sections are measured as a function of the transverse momenta of the four highest jets.

View Article and Find Full Text PDF

Pteridine reductase 1 (PTR1) is a folate and pterin pathway enzyme unique for pathogenic trypanosomatids. As a validated drug target, PTR1 has been the focus of recent research efforts aimed at finding more effective treatments against human parasitic diseases such as leishmaniasis or sleeping sickness. Previous PTR1-centered structural studies highlighted the enzyme characteristics, such as flexible regions around the active site, highly conserved structural waters, and species-specific differences in pocket properties and dynamics, which likely impacts the binding of natural substrates and inhibitors.

View Article and Find Full Text PDF

The structure of nucleons is multidimensional and depends on the transverse momenta, spatial geometry, and polarization of the constituent partons. Such a structure can be studied using high-energy photons produced in ultraperipheral heavy-ion collisions. The first measurement of the azimuthal angular correlations of exclusively produced events with two jets in photon-lead interactions at large momentum transfer is presented, a process that is considered to be sensitive to the underlying nuclear gluon polarization.

View Article and Find Full Text PDF

Mesenchymal stem cell engineering by ARCA analog-capped mRNA.

Mol Ther Nucleic Acids

September 2023

Center for Advanced Imaging Research, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, MD 21201, USA.

Article Synopsis
  • The study examines factors affecting mRNA engineering of mesenchymal stem cells (MSCs), focusing on transfection methods, mRNA purification, and capping types.
  • Results show that Lipofectamine 2000 is superior to TransIT for MSC transfection, while HPLC purification is essential for maintaining MSC health.
  • It concludes that using Lipofectamine 2000 with HPLC-purified mRNA and β-S-ARCA D1 capping achieves enhanced protein production, albeit with reduced MSC metabolic activity.
View Article and Find Full Text PDF

Two derivatives of a "super stable" Blatter radical (1,3-diphenyl-7-trifluoromethyl-1,4-dihydrobenzo[][1,2,4]triazin-4-yl) with N(1)-Ar = 2-CFCH and 2-MeOCH were obtained and investigated using XRD and SQUID magnetometry methods. The investigation revealed strong antiferromagnetic interactions in both radicals, which are described using the Hatfield model. For the latter radical, an abrupt and reversible change in the () plot was observed at 29 K.

View Article and Find Full Text PDF

Biocompatible zeolite-dye composites with anti-amyloidogenic properties.

Int J Biol Macromol

November 2023

Department of Biophysics, Institute of Experimental Physics, Slovak Academy of Sciences, Watsonova 47, 04001, Kosice, Slovakia. Electronic address:

One of the most attractive approaches in biomedicine and pharmacy is the application of multifunctional materials. The mesoporous structure of clinoptilolite (CZ) absorbs various types of substances and can be used as a model for studying the carriers for targeted drug delivery with controlled release. CZ-dye composites are fabricated by incorporation into clinoptilolite pores commonly used dyes, aluminum phthalocyanine, zinc porphine, and hypericin.

View Article and Find Full Text PDF