1 results match your criteria: "Institute of Engineering Medicine Beijing Institute of Technology Beijing P. R. China.[Affiliation]"

Membrane-destabilizing ionizable lipid empowered imaging-guided siRNA delivery and cancer treatment.

Exploration (Beijing)

August 2021

School of Life Science, Advanced Research Institute of Multidisciplinary Science, Key Laboratory of Molecular Medicine and Biotherapy, Institute of Engineering Medicine Beijing Institute of Technology Beijing P. R. China.

One of the imperative medical requirements for cancer treatment is how to establish an imaging-guided nanocarrier that combines therapeutic and imaging agents into one system. siRNA therapeutics have shown promising prospects in controlling life-threatening diseases. However, it is still challenging to develop siRNA formulations with excellent cellular entry capability, efficient endosomal escape, and simultaneous visualization.

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