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In the first months of the Spanish Civil War, the Spanish doctor Frederic Duran Jordà developed a new method of blood transfusion which overcame the era of direct arm-to-arm transfusions. While Duran was experimenting in Barcelona and the Aragon front, hundreds of foreign doctors came to Spain with the help of internationalist associations and offered their services to the Republican government. The Czechoslovak Dr Karel Holubec entered Spain in May 1937 and practiced in a mobile hospital funded by the Czechoslovak Committee to Aid Democratic Spain, receiving blood from Duran's laboratory.

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