Causally Mapping the Cerebellum in Children and Young Adults: from Motor to Cognition.

While the cerebellum's role in orchestrating motor execution and routines is well established, its functional role in supporting cognition is less clear. Previous studies claim that motricity and cognition are mapped in different areas of the cerebellar cortex, with an anterior/posterior dichotomy. However, most of the studies supporting this claim either use correlational methods (neuroimaging) or are lesion studies that did not consider central covariates (such as age, gender, treatment presence, and deep nuclei impairment) known to influence motor and cognitive recoveries in patients.

Feeling good, approaching the positive.

Introduction: Approach and avoidance behaviors have been extensively studied in cognitive science as a fundamental aspect of human motivation and decision-making. The Approach-Avoidance Bias (AAB) refers to the tendency to approach positive stimuli faster than negative stimuli and to avoid negative stimuli faster than positive ones. Affect and arousal in involved individuals are assumed to play a crucial role in the AAB but many questions in that regard remain open.

Translation, Validity, and Reliability of Depression Literacy Questionnaire in Iranian Young Adults.

Background: Depression literacy has notable advantages in the early identification and treatment of depression. The current study was conducted with the aim of translating and investigating the validity and reliability of the Depression Literacy Questionnaire (D-Lit) in Iranian young adults.

Methods: The current study entailed a descriptive-analytical study in which the translation, validation, and preparation of the Persian version of D-Lit were conducted.

Diagnosis of Schizophrenia and Its Subtypes Using MRI and Machine Learning.

Purpose: The neurobiological heterogeneity present in schizophrenia remains poorly understood. This likely contributes to the limited success of existing treatments and the observed variability in treatment responses. Our objective was to employ magnetic resonance imaging (MRI) and machine learning (ML) algorithms to improve the classification of schizophrenia and its subtypes.

Education moderates the association between motor involvement and executive status in ALS.

Background: This study aimed to determine whether educational attainment-a common proxy of cognitive reserve (CR)-influences the association between motor and cognitive/behavioural outcomes in a large cohort of ALS patients without dementia.

Methods: N = 726 ALS patients without FTD were assessed for motor (ALSFRS-R), cognitive (Edinburgh Cognitive and Behavioural ALS Screen, ECAS) and behavioural outcomes (ECAS-Carer Interview, ECAS-CI). CR was operationalized via educational attainment (in years).

Strontium isoscape of sub-Saharan Africa allows tracing origins of victims of the transatlantic slave trade.

Strontium isotope (Sr/Sr) analysis with reference to strontium isotope landscapes (Sr isoscapes) allows reconstructing mobility and migration in archaeology, ecology, and forensics. However, despite the vast potential of research involving Sr/Sr analysis particularly in Africa, Sr isoscapes remain unavailable for the largest parts of the continent. Here, we measure the Sr/Sr ratios in 778 environmental samples from 24 African countries and combine this data with published data to model a bioavailable Sr isoscape for sub-Saharan Africa using random forest regression.

Are three zebras more than three frogs: examining conceptual and physical congruency in numerosity judgements of familiar objects.

Researchers in numerical cognition have extensively studied the number sense-the innate human ability to extract numerical information from the environment quickly and effortlessly. Much of this research, however, uses abstract stimuli (e.g.

Exploring foreign language anxiety and resting-state EEG alpha asymmetry.

Anxiety experienced when interacting in a foreign language hinders communication through detrimental behavioral, cognitive, and somatic effects. Despite its impact, there is limited research on how neural asymmetry relates to foreign language anxiety (FLA). While researchers have investigated FLA through brain imaging, there remains an absence of studies examining its correlation with frontal alpha asymmetry.

Dancing robots: aesthetic engagement is shaped by stimulus and knowledge cues to human animacy.

Introduction: Artificial intelligence (AI) and robots are increasingly shaping the aesthetic preferences of art consumers, influencing how they perceive and engage with artistic works. This development raises various questions: do cues to the humanness of the origin of an artwork or artist influence our aesthetic preferences?.

Methods: Across two experiments, we investigated how the perception and appreciation of dance is influenced by cues to human animacy.

The point of no return in the Emotional Stop-Signal Task: A matter of affect or method?

An affective variant of the Stop-Signal task was used to study the interaction between emotion and response inhibition (RI) in healthy young participants. The task involved the covert presentation of emotional faces as go stimuli, as well as a manipulation of motivation and affect by inducing a negative mood through the assignment of unfair punishment. In the literature on emotion and RI, there are contrasting findings reflecting the variability in the method used to calculate the RI latency, namely the Stop-Signal Reaction Time (SSRT).

Large language models surpass human experts in predicting neuroscience results.

Scientific discoveries often hinge on synthesizing decades of research, a task that potentially outstrips human information processing capacities. Large language models (LLMs) offer a solution. LLMs trained on the vast scientific literature could potentially integrate noisy yet interrelated findings to forecast novel results better than human experts.

High-level visual prediction errors in early visual cortex.

Perception is shaped by both incoming sensory input and expectations derived from our prior knowledge. Numerous studies have shown stronger neural activity for surprising inputs, suggestive of predictive processing. However, it is largely unclear what predictions are made across the cortical hierarchy, and therefore what kind of surprise drives this up-regulation of activity.

The Interplay of Exogenous Cannabinoid Use on Anandamide and 2-Arachidonoylglycerol in Anxiety: Results from a Quasi-Experimental Ad Libitum Study.

The public is increasingly reporting using cannabis for anxiety relief. Both cannabis use and the endocannabinoid system have been connected with anxiety relief/anxiolytic properties, but these relationships are complex, and the underlying mechanisms for them are unclear. : Work is needed to understand how the endocannabinoid system, including the endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol (2-AG), may be impacted by the main constituents of cannabis, Δ9-tetrahydrocannabinol (THC), and cannabidiol (CBD).

Cost and benefit of parafoveal information during reading acquisition as revealed by finger movement patterns.

Contrary to expert readers, children learning to read have limited ability to preprocess letters in parafoveal vision. Parafoveal letters induce crowding cost: the features of neighboring letters interfere with target letter identification. We longitudinally studied the weight of parafoveal cost and benefit in two group of children (N = 42), during their first school year (Group 1) and at the end of second school year (Groupe 2).

Just-in-time: Gaze guidance in natural behavior.

Natural eye movements have primarily been studied for over-learned activities such as tea-making, sandwich-making, and hand-washing, which have a fixed sequence of associated actions. These studies demonstrate a sequential activation of low-level cognitive schemas facilitating task completion. However, whether these action schemas are activated in the same pattern when a task is novel and a sequence of actions must be planned in the moment is unclear.

Disparities in structural brain imaging in older adults from rural communities in Southern Nevada.

Introduction: Identifying the associations between rural-living or neighborhood disadvantage and neurobiology may clarify rural-urban disparities in older adults with cognitive impairment related to Alzheimer's disease.

Methods: We examined rural-urban differences and neighborhood disadvantages in brain cortical thickness (CT) measures among 71 rural and 87 urban-dwelling older adults. Analysis of covariance was used to test each FreeSurfer-derived CT measures' associations with rural-urban living, clinical impairment status, and their interactions.

for studying social interaction: A scoping review of simultaneous brain and body measurements.

We systematically investigated the application of embodied hyperscanning methodologies in social neuroscience research. Hyperscanning enables the simultaneous recording of neurophysiological and physiological signals from multiple participants. We highlight the trend toward integrating Mobile Brain/Body Imaging (MoBI) within the 4E research framework, which emphasizes the interconnectedness of brain, body, and environment.

Edible cannabis for chronic low back pain: associations with pain, mood, and intoxication.

Introduction: Cannabis, commonly known for both therapeutic and intoxicating effects, is gaining accessibility on legal markets and traction as a potential alternative therapy for pain mediation, particularly in those suffering from chronic low back pain. However, the effectiveness in this population of legal market forms of cannabis, particularly commonly used edibles, is unknown.

Methods: Therefore, this study utilized a naturalistic prospective design where participants with chronic low back pain with intentions to initiate cannabis use for treatment were recruited and self-selected edible cannabis products containing varying amounts of delta- 9 tetrahydrocannabinol (THC) and cannabidiol (CBD).

Pre-choice midbrain fluctuations affect self-control in food choice: A functional magnetic resonance imaging (fMRI) study.

Recent studies have shown that spontaneous pre-stimulus fluctuations in brain activity affect higher-order cognitive processes, including risky decision-making, cognitive flexibility, and aesthetic judgments. However, there is currently no direct evidence to suggest that pre-choice activity influences value-based decisions that require self-control. We examined the impact of fluctuations in pre-choice activity in key regions of the reward system on self-control in food choice.

Moral Learning and Decision-Making Across the Lifespan.

Moral learning and decision-making are crucial throughout our lives, from infancy to old age. Emerging evidence suggests that there are important differences in learning and decision-making in moral situations across the lifespan, and these are underpinned by co-occurring changes in the use of model-based values and theory of mind. Here, we review the decision neuroscience literature on moral choices and moral learning considering four key concepts.

Idiosyncratic gesture use in a mother-infant dyad in chimpanzees (Pan troglodytes schweinfurthii) in the wild.

One promising method to tackle the question, "In which modality did language evolve?" is by studying the ontogenetic trajectory of signals in human's closest living relatives, including chimpanzees (Pan troglodytes). Concerning gestures, current debates centre on four different hypotheses: "phylogenetic ritualization", "social transmission through imitation", "ontogenetic ritualization", and "social negotiation". These differ in their predictions regarding idiosyncratic gestures, making such occurrences a crucial area of investigation.