Interactions between Sleep and Emotions in Humans and Animal Models.

Recently, increased interest and efforts were observed in describing the possible interaction between sleep and emotions. Human and animal model studies addressed the implication of both sleep patterns and emotional processing in neurophysiology and neuropathology in suggesting a bidirectional interaction intimately modulated by complex mechanisms and factors. In this context, we aimed to discuss recent evidence and possible mechanisms implicated in this interaction, as provided by both human and animal models in studies.

Lack of general learning ability factor in a rat test battery measuring a wide spectrum of cognitive domains.

: In the framework of a larger project aiming to test putative cognitive enhancer drugs in a system with improved translational validity, we established a rodent test battery, where different, clinically relevant cognitive domains were investigated in the same animal population. The aim of the current study was to check whether performances in the different tasks representing different cognitive functions are assay-specific or may originate in an underlying general learning ability factor. : In the experiments 36 Long-Evans and 36 Lister Hooded rats were used.

Social Stimulation by the Owner Increases Dogs' () Social Susceptibility in a Food Choice Task-The Possible Effect of Endogenous Oxytocin Release.

Recent evidence suggests a human-like susceptibility to social influence in dogs. For example, dogs tend to ignore their 'natural' preference for the larger amount of food after having seen a human's explicit preference for a smaller quantity. However, it is still unclear whether this tendency to conform to the partner's behaviour can be influenced by social stimuli and/or the neurohormone oxytocin as primers to prosocial predispositions.

Alternative female and male developmental trajectories in the dynamic balance of human visual perception.

The numerous multistable phenomena in vision, hearing and touch attest that the inner workings of perception are prone to instability. We investigated a visual example-binocular rivalry-with an accurate no-report paradigm, and uncovered developmental and maturational lifespan trajectories that were specific for age and sex. To interpret these trajectories, we hypothesized that conflicting objectives of visual perception-such as stability of appearance, sensitivity to visual detail, and exploration of fundamental alternatives-change in relative importance over the lifespan.

Factor Structure, Psychometric Properties, and Validation of the Hungarian Version of the Experiences in Close Relationships Revised (ECR-R-HU) Questionnaire in a Nationally Representative Community Sample.

The Experiences in Close Relationships - Revised (ECR-R) is a widely used self-report instrument to assess adult romantic attachment. The present study aimed at examining the factor structure, reliability, construct validity, and temporal stability of the Hungarian version of the ECR-R (ECR-R-HU) in a nationally representative community sample ( = 958). The original avoidance and anxiety dimensions of the ECR-R could only be identified, when reversed-item method factors and residual correlations were included in the confirmatory factor analysis (CFA).

Intact fluency in autism? A comprehensive approach of verbal fluency task including word imageability and concreteness.

Verbal fluency is a cognitive function reflecting executive functions and the ability to retrieve the appropriate information from memory quickly. Previous studies reported conflicting results-impaired and intact verbal fluency-in autism spectrum disorder (ASD). Most studies concentrate on overall word productivity, errors, perseverations, clustering, or switching.

Perisomatic Inhibition and Its Relation to Epilepsy and to Synchrony Generation in the Human Neocortex.

Inhibitory neurons innervating the perisomatic region of cortical excitatory principal cells are known to control the emergence of several physiological and pathological synchronous events, including epileptic interictal spikes. In humans, little is known about their role in synchrony generation, although their changes in epilepsy have been thoroughly investigated. This paper demonstraits how parvalbumin (PV)- and type 1 cannabinoid receptor (CB1R)-positive perisomatic interneurons innervate pyramidal cell bodies, and their role in synchronous population events spontaneously emerging in the human epileptic and non-epileptic neocortex, in vitro.

Novel Lysine-Rich Delivery Peptides of Plant Origin ERD and Human S100: The Effect of Carboxyfluorescein Conjugation, Influence of Aromatic and Proline Residues, Cellular Internalization, and Penetration Ability.

The need for novel drug delivery peptides is an important issue of the modern pharmaceutical research. Here, we test K-rich peptides from plant dehydrin ERD14 (ERD-A, ERD-B, and ERD-C) and the C-terminal CPP-resembling region of S100A4 (S100) using the 5(6)-carboxyfluorescein (Cf) tag at the N-terminus. Via a combined pH-dependent NMR and fluorescence study, we analyze the effect of the Cf conjugation/modification on the structural behavior, separately investigating the (5)-Cf and (6)-Cf forms.

A Process-Oriented View of Procedural Memory Can Help Better Understand Tourette's Syndrome.

Tourette's syndrome (TS) is a neurodevelopmental disorder characterized by repetitive movements and vocalizations, also known as tics. The phenomenology of tics and the underlying neurobiology of the disorder have suggested that the altered functioning of the procedural memory system might contribute to its etiology. However, contrary to the robust findings of impaired procedural memory in neurodevelopmental disorders of language, results from TS have been somewhat mixed.

The key to superior memory encoding under stress: the relationship between cortisol response and mnemonic discrimination.

Some previous studies have shown that increased stress hormone levels have beneficial effects on memory encoding; however, there is no clear consensus on which encoding-related processes are affected by stress hormones. In the present study, we investigated the relationship between interindividual differences in neuroendocrine response to acute stress and interference resolution (i.e.

The relationship between cognitive control and lexical conflict resolution in developmental dyslexia.

Previous studies have revealed that cognitive control functions contribute to the resolution of lexical interference. Both cognitive control (CC) deficits and reduced speed of lexical retrieval in Rapid Automatized Naming (RAN) tasks are characteristics of Developmental Dyslexia (DD), but it is still not fully understood how these deficits relate to each other and to reading problems. To examine this question, we tested adolescents with DD (n = 38), poor readers (PR; n = 25) and typical readers (TR; n = 33) matched on age and IQ, on CC functions with Stroop, Stop Signal, Simon, Backward Digit Span and n-back tasks and on lexical retrieval and lexical conflict resolution with RAN of pictures in semantically homogeneous vs.

Developmental features of sleep electrophysiology in family dogs.

Age-related differences in dog sleep and the age at which dogs reach adulthood as indexed by sleep electrophysiology are unknown. We assessed, in (1) a Juvenile sample (n = 60) of 2-14-month-old dogs (weight range: 4-68 kg), associations between age, sleep macrostructure, and non-rapid eye movement (NREM) EEG power spectrum, whether weight moderates associations, and (2) an extended sample (n = 91) of 2-30-months-old dogs, when sleep parameters stabilise. In Juvenile dogs, age was positively associated with time in drowsiness between 2 and 8 months, and negatively with time in rapid eye movement (REM) sleep between 2 and 6 months.

Cautious or causal? Key implicit sequence learning paradigms should not be overlooked when assessing the role of DLPFC (Commentary on Prutean et al.).

The role of the dorsolateral prefrontal cortex (DLPFC) in implicit sequence/statistical learning has received considerable attention in recent cognitive neuroscience research. Studies have used non-invasive brain stimulation methods to test whether the DLPFC plays a role in the incidental acquisition and expression of implicit sequence learning. In a recent study, Prutean et al.

Distinct aspects of emotion dysregulation differentially correspond to magnitude and slope of the late positive potential to affective stimuli.

Emotion dysregulation (ED) is a transdiagnostic risk factor for several forms of psychopathology. One established, integrative conceptualisation of ED that has informed our understanding of psychopathology (Gratz, K. L.

Sleep-spindle frequency: Overnight dynamics, afternoon nap effects, and possible circadian modulation.

Homeostatic and circadian processes play a pivotal role in determining sleep structure, timing, and quality. In sharp contrast with the wide accessibility of the electroencephalogram (EEG) index of sleep homeostasis, an electrophysiological measure of the circadian modulation of sleep is still unavailable. Evidence suggests that sleep-spindle frequencies decelerate during biological night.

Does Creativity Influence Visual Perception? - An Event-Related Potential Study With Younger and Older Adults.

We do not know enough about the cognitive background of creativity despite its significance. Using an active oddball paradigm with unambiguous and ambiguous portrait paintings as the standard stimuli, our aim was to examine whether: creativity in the figural domain influences the perception of visual stimuli; any stages of visual processing; or if healthy aging has an effect on these processes. We investigated event related potentials (ERPs) and applied ERP decoding analyses in four groups: younger less creative; younger creative; older less creative; and older creative adults.

Shorter Contextual Timescale Rather Than Memory Deficit in Aging.

Many aspects of cognitive ability and brain function that change as we age look like deficits on account of measurable differences in comparison to younger adult groups. One such difference occurs in auditory sensory responses that index perceptual learning. Meta-analytic findings show reliable age-related differences in auditory responses to repetitive patterns of sound and to rare violations of those patterns, variously attributed to deficits in auditory sensory memory and inhibition.

Interhemispheric asymmetry during NREM sleep in the dog.

Functional hemispheric asymmetry was evidenced in many species during sleep. Dogs seem to show hemispheric asymmetry during wakefulness; however, their asymmetric neural activity during sleep was not yet explored. The present study investigated interhemispheric asymmetry in family dogs using non-invasive polysomnography.

Self-care tooling innovation in a disabled kea (Nestor notabilis).

Tooling is associated with complex cognitive abilities, occurring most regularly in large-brained mammals and birds. Among birds, self-care tooling is seemingly rare in the wild, despite several anecdotal reports of this behaviour in captive parrots. Here, we show that Bruce, a disabled parrot lacking his top mandible, deliberately uses pebbles to preen himself.

Older Adults Automatically Detect Age of Older Adults' Photographs: A Visual Mismatch Negativity Study.

The human face is one of the most frequently used stimuli in vMMN (visual mismatch negativity) research. Previous studies showed that vMMN is sensitive to facial emotions and gender, but investigations of age-related vMMN differences are relatively rare. The aim of this study was to investigate whether the models' age in photographs were automatically detected, even if the photographs were not parts of the ongoing task.

Access to Procedural Memories After One Year: Evidence for Robust Memory Consolidation in Tourette Syndrome.

Tourette syndrome is a childhood-onset neurodevelopmental disorder characterized by motor and vocal tics. On the neural level, tics are thought to be related to the disturbances of the cortico-basal ganglia-thalamo-cortical loops, which also play an important role in procedural learning. Several studies have investigated the acquisition of procedural information and the access to established procedural information in TS.

The implicit reward value of the owner's face for dogs.

It is increasingly assumed that domestication has equipped dogs with unique socio-cognitive skills, which raises the possibility of intriguing parallels between the social motivational systems of the two species. However, the positive incentive value of human facial stimuli is a largely unexplored area. Here, we investigated whether the owner's face serves as a social reinforcer.

Development of Preschoolers' Understanding of Zero.

While knowledge on the development of understanding positive integers is rapidly growing, the development of understanding zero remains not well-understood. Here, we test several components of preschoolers' understanding of zero: Whether they can use empty sets in numerical tasks (as measured with comparison, addition, and subtraction tasks); whether they can use empty sets soon after they understand the cardinality principle (cardinality-principle knowledge is measured with the give-N task); whether they know what the word "zero" refers to (tested in all tasks in this study); and whether they categorize zero as a number (as measured with the smallest-number and is-it-a-number tasks). The results show that preschoolers can handle empty sets in numerical tasks as soon as they can handle positive numbers and as soon as, or even earlier than, they understand the cardinality principle.

Microstructural changes in human ingestive behavior after Roux-en-Y gastric bypass during liquid meals.

BACKGROUNDRoux-en-Y gastric bypass (RYGB) decreases energy intake and is, therefore, an effective treatment of obesity. The behavioral bases of the decreased calorie intake remain to be elucidated. We applied the methodology of microstructural analysis of meal intake to establish the behavioral features of ingestion in an effort to discern the various controls of feeding as a function of RYGB.