2 results match your criteria: "Institute of Cardiology of Cruz Alta[Affiliation]"
TRF1 as a major contributor for telomeres' shortening in the context of obesity.
Free Radic Biol Med
December 2018
Postgraduate Program: Biochemistry, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil; Group of Inflammation and Cellular Senescence and Laboratory of Molecular Biology and Bioinformatics, Department of Biochemistry/ICBS, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil; Postgraduate Program in Cellular and Molecular Biology, School of Sciences, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, RS, Brazil. Electronic address:
Obesity is a prevalent multifactorial chronic disorder characterized by metabolic dysregulation. Sustained pro-oxidative mediators trigger harmful consequences that reflect at systemic level and contribute for the establishment of a premature senescent phenotype associated with macromolecular damage (DNA, protein, and lipids). Telomeres are structures that protect chromosome ends and are associated with a six-protein complex called the shelterin complex and subject to regulation.
View Article and Find Full Text PDFHospitalization due to conditions sensitive to primary care and expansion of the Family Health Program in Brazil: an ecological study.
Rev Bras Epidemiol
December 2014
Institute of Cardiology of Cruz Alta, Universidade de Cruz Alta, Porto Alegre, RS, Brazil.
Objective: To evaluate the relationship between hospitalization due to conditions that are sensitive to primary care and the population coverage by the Family Health Strategy (ESF) Units of the Brazilian Federation Units in the last decade.
Methods: This is an ecological study that investigated preventable hospitalizations and coverage of primary health care in Brazil in the historic series from 1998 to 2006. Statistical analysis was performed using the Pearson correlation test and simple linear regression.