4 results match your criteria: "Institute of Biomedical Engineering of Central South University[Affiliation]"

Background: Conventional transabdominal ultrasound usually fails to visualize parts of the ureter or extrahepatic bile duct covered by bowel gas. In this study, we propose a new method for gaining acoustic access to the ureters and extrahepatic bile duct to help determine the nature of obstruction to these structures when conventional transabdominal ultrasound fails.

Methods: The normal saline retention enema method, that is, using normal saline-filled colons to gain acoustic access to the bilateral ureters and extrahepatic bile duct and detecting the lesions with transabdominal ultrasonic diagnostic apparatus, was applied to 777 patients with obstructive lesions, including 603 with hydroureter and 174 with dilated common bile duct, which were not visualized by conventional ultrasonography.

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Preparation and characterization of tegafur magnetic thermosensitive liposomes.

Pharm Dev Technol

December 2009

National Hepatobiliary & Enteric Surgery Research Center, Ministry of Health, Central South University, National Key Laboratory of Nanobiological Technology, Institute of Biomedical Engineering of Central South University, Changsha, Hunan, P.R. China.

The purpose was to study the preparation and properties of tegafur magnetic thermosensitive liposomes. The method was to employ an improved chemical coprecipitation method for preparing nano-magnetic particles and a reverse-phase evaporation and ultrasonic method for preparing tegafur magnetic thermosensitive liposomes. The results showed that tegafur magnetic thermosensitive liposomes were prepared successfully.

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Preparation of matrine ethosome, its percutaneous permeation in vitro and anti-inflammatory activity in vivo in rats.

J Liposome Res

September 2010

National Hepatobiliary and Enteric Surgery Research Center, Ministry of Health, Institute of Biomedical Engineering of Central South University, No. 87 Xiangya Road, Changsha, Hunan Province, China.

The aim of this work was to evaluate the preparation of matrine ethosome and the percutaneous permeation in vitro and the anti-inflammatory activity in vivo in the rat skin. The matrine ethosomes were prepared by the ethanol injection-sonication method. The particle size of the ethosomes was measured by a laser particle-size analyzer, and the entrapment efficiency was detected by ultracentrifugation.

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[Preparation of tegafur magnetic long-circulating thermosensitive liposomes and its pharmacokinetics in rats].

Nan Fang Yi Ke Da Xue Xue Bao

October 2008

National Hepatobiliary and Enteric Surgery Research Center, Ministry of Health, Institute of Biomedical Engineering of Central South University, Changsha 410008, China.

Objective: To prepare tegafur magnetic long-circulating thermosensitive liposomes and study its pharmacokinetics and targeting properties in rats.

Methods: Tegafur magnetic long-circulating thermosensitive liposomes were prepared by reversed phase-ultrasound method and its concentration in various organs of rats were detected with high-performance liquid chromatography.

Results: The average size of tegafur magnetic long-circulating thermosensitive liposomes was about 126 nm, which showed strong ferromagnetism and superparamagnetism.

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