Advances in automated real-time flow cytometry for monitoring of bioreactor processes.

Flow cytometry and its technological possibilities have greatly advanced in the past decade as analysis tool for single cell properties and population distributions of different cell types in bioreactors. Along the way, some solutions for automated real-time flow cytometry (ART-FCM) were developed for monitoring of bioreactor processes without operator interference over extended periods with variable sampling frequency. However, there is still great potential for ART-FCM to evolve and possibly become a standard application in bioprocess monitoring and process control.

Production of β-carotene with CCAP19/18 at physically simulated outdoor conditions.

Batch growth and β-carotene production of CCAP19/18 was investigated in flat-plate gas-lift photobioreactors with a light path of 2 cm, operated in physically simulated outdoor conditions. CCAP19/18 showed robust growth with respect to pH 8.0-9.

Validated numerical fluid simulation of a thin-layer cascade photobioreactor in OpenFOAM.

Recently, microalgae have been considered as a promising alternative for the production of biofuels from CO. For the efficient cultivation of these microalgae, several types of photobioreactors have been designed and Pilot scale photobioreactors have been used to assess the performance of these reactors. Therein the primarily investigated reactor type is the Raceway Pond.