1 results match your criteria: "Institute of Basic Medical Science University of Oslo[Affiliation]"
Toll-like receptor 9 signaling after myocardial infarction: Role of p66ShcA adaptor protein.
Biochem Biophys Res Commun
February 2023
Department of Molecular Medicine, Institute of Basic Medical Science University of Oslo, Norway. Electronic address:
During myocardial infarction, cellular debris is released, causing a sterile inflammation via pattern recognition receptors. These reactions amplify damage and promotes secondary heart failure. The pattern recognition receptor, Toll-like receptor 9 (TLR9) detects immunogenic fragments of endogenous DNA, inducing inflammation by NFκB.
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