Improving Image Quality and Decreasing SAR With High Dielectric Constant Pads in 3 T Fetal MRI.

Background: At high magnetic fields, degraded image quality due to dielectric artifacts and elevated specific absorption rate (SAR) are two technical challenges in fetal MRI.

Purpose: To assess the potential of high dielectric constant (HDC) pad in increasing image quality and decreasing SAR for 3 T fetal MRI.

Study Type: Prospective.

pH-Triggered Phase Transitions, Coexposure of (001) and (110) Facets, and Oxygen Vacancies in BiOCl Photocatalysts.

Bismuth oxychloride (BiOCl) is known for its unique layered microstructure, which plays a pivotal role in enhancing its photocatalytic properties. This study introduces a novel strategy for controlling the phase composition, facet orientation, and oxygen vacancy formation in BiOCl through precise pH adjustment during the synthesis. By employing a hydrothermal method, we systematically varied the pH to produce distinct BiOCl phases and conducted detailed structural and photocatalytic analyses.

The Cooperativity of Atomic Fluctuations in Highly Supercooled Glass-Forming Metallic Melts.

The behavior of supercooled glass-forming metals depends on the cooperative atomic fluctuations caused by dynamic heterogeneities in the melt. These spatial and temporal heterogeneities form dynamic clusters, which are regions of cooperative rearrangement (CRR). In this study, the macroscopic kinetics and the correlation length , of the CRR, are derived for PtCuNiP and PdCuNiP metallic glass-formers by fast differential scanning calorimetry near the glass transition.

Comparison of nanoLC-MALDI-MS/MS with nanoLC-TIMS-MS/MS in the proteomic analysis of extracellular vesicles of bronchoalveolar lavage fluid.

The study aims to evaluate and compare two advanced proteomic techniques, nanoLC-MALDI-MS/MS and nanoLC-TIMS-MS/MS, in characterizing extracellular vesicles (EVs) from the bronchoalveolar lavage fluid (BALF) of patients with asthma and idiopathic pulmonary fibrosis (IPF). Pulmonary diseases, driven by pollutants and infections, often necessitate detailed analysis of BALF to identify diagnostic biomarkers and therapeutic targets. EVs, which include exosomes, microvesicles, and apoptotic bodies, are isolated using filtration and ultracentrifugation, and their morphology, concentration, and size distribution are assessed through transmission electron microscopy (TEM) and nanoparticle tracking analysis (NTA).

Radical Brook rearrangement: past, present, and future.

The Brook rearrangement has emerged as one of the most pivotal transformations in organic chemistry, with broad applications spanning organic synthesis, drug design, and materials science. Since its discovery in the 1950s, the anion-mediated Brook rearrangement has been extensively studied, laying the groundwork for the development of numerous innovative reactions. In contrast, the radical Brook rearrangement has garnered comparatively less attention, primarily due to the challenges associated with the controlled generation of alkoxyl radicals under mild conditions.

Enhancing CO oxidation performance by controlling the interconnected pore structure in porous three-way catalyst particles.

Highly ordered porous structured particles comprising three-way catalyst (TWC) nanoparticles have attracted attention because of their remarkable catalytic performance. However, the conditions for controlling their pore arrangement to form interconnected pore structures remain unclear. In particular, the correlation between framework thickness (distance between pores) or macroporosity and the diffusion of gaseous reactants to achieve a high catalytic performance has not been extensively discussed.

Comparing to three other enteric pathogens in OligoMM mice reveals pathogen-specific host and microbiota responses.

, non-typhoidal spp., and enteropathogenic/enterohemorrhagic (EPEC/EHEC) are leading causes of food-borne illness worldwide. has been used to model EPEC and EHEC infection in mice.

Bicycle-inspired simple balance control method for quadruped robots in high-speed running.

This paper explores the applicability of bicycle-inspired balance control in a quadruped robot model. Bicycles maintain stability and change direction by intuitively steering the handle, which induces yaw motion in the body frame and generates an inertial effect to support balance. Inspired by this balancing strategy, we implemented a similar mechanism in a quadruped robot model, introducing a yaw trunk joint analogous to a bicycle's steering handle.

Android avatar improves educational effects by embodied anthropomorphization.

After the COVID-19 pandemic, the adoption of distance learning has been accelerated in educational institutions in multiple countries. In addition to using a videoconferencing system with camera images, avatars can also be used for remote classes. In particular, an android avatar with a sense of presence has the potential to provide higher quality education than a video-recorded lecture.

The Combined Impact of Curcumin: Piperine and Sorafenib on microRNAs and Different Pathways in Breast Cancer Cells.

Unlabelled: Breast cancer is the most common malignancy in the women. Chemotherapy is a crucial part of breast cancer treatment especially for advanced and metastatic forms of the disease. However, chemotherapy has limitations due to tumor heterogeneity, chemoresistance, and side effects.

Advances in fear memory erasure and its neural mechanisms.

Background: In nature, animals must learn to recognize danger signals and respond immediately to threats to improve their environmental adaptation. However, excessive fear responses can lead to diseases such as post-traumatic stress disorder, wherein traumatic events result in persistent traumatic memories. Therefore, erasing pathological fear memories is a crucial topic in neuroscience for understanding the nature of memories and treating clinically relevant diseases.

The global trends and distribution in tumor-infiltrating lymphocytes over the past 49 years: bibliometric and visualized analysis.

Background: The body of research on tumor-infiltrating lymphocytes (TILs) is expanding rapidly; yet, a comprehensive analysis of related publications has been notably absent.

Objective: This study utilizes bibliometric methodologies to identify emerging research hotspots and to map the distribution of tumor-infiltrating lymphocyte research.

Methods: Literature from the Web of Science database was analyzed and visualized using VOSviewer, CiteSpace, Scimago Graphica, R-bibliometrix, and R packages.

Chemokine family significance and prognostic value in colorectal cancer.

Background: Colorectal cancer (CRC) poses a substantial global health concern, exhibits inconspicuous early symptoms, and is typically diagnosed at advanced stages leading to unfavorable outcomes. The intricate tumor microenvironment plays a crucial role in CRC development and progression, where chemokines contribute significantly. These chemokines exhibit widespread expression within tumor cells, facilitating immune cell infiltration, angiogenesis, and the establishment of distant metastases.

A bibliometric analysis of optic atrophy from 2003 to 2023: research trends and hot spots.

Background: Optic atrophy (OA) is primarily caused by damage to the retinal pathway system, including widespread degeneration of retinal ganglion cells and axons, leading to visual impairment and blindness. Despite its clinical significance and diverse etiological factors, there is currently a lack of comprehensive bibliometric analyses exploring research trends and hotspots within this field.

Method: This study retrieved relevant literature on OA published between 2003 and 2023 from the Web of Science Core Collection database.

Factors Associated With the Development of Heart Failure Following Acute Coronary Syndrome: A Systematic Review and Meta-Analysis.

Acute coronary syndrome (ACS) remains a major global health burden, encompassing a spectrum of conditions from unstable angina to acute myocardial infarction. Despite advancements in early detection and management, ACS is often complicated by the development of heart failure. This systematic review and meta-analysis aimed to identify factors associated with the development of heart failure following acute coronary syndrome.

Bibliometric Analysis of Research on Lip Prints.

Lip prints, or cheiloscopy, are unique patterns of grooves and wrinkles, gaining prominence in forensic science as reliable tools for personal identification, akin to fingerprints and DNA profiling. Advances in imaging techniques have enhanced their forensic applicability. This study conducts a bibliometric analysis to explore global research trends, key contributors, and thematic developments in lip print research.

Interaction of human gut microbiota and local immune system in progression of colorectal adenoma (MIMICA-1): a protocol for a prospective, observational cohort study.

Introduction: The current understanding of colorectal carcinogenesis is based on the adenoma-carcinoma sequence, where genetics, intestinal microbiota changes and local immunity shifts seem to play the key roles. Despite the emerging evidence of dysbiotic intestinal state and immune-cell infiltration changes in patients with colorectal adenocarcinoma, early and advanced adenoma as precursors of colorectal cancer, and carcinoma as the following progression, are rather less studied. The newly colon-site adapted AI-based analysis of immune infiltrates is able to predict long-term outcomes of colon carcinoma.

Liquid chromatography-tandem mass spectrometry for the quantification of ripretinib and its metabolites DP-5439 in human plasma.

Background: Ripretinib, a broad-spectrum tyrosine kinase inhibitor, has been approved for the treatment of advanced gastrointestinal stromal tumors in adult patients. Clinical studies have shown that higher exposure of ripretinib correlates with improved efficacy, highlighting the potential clinical significance of therapeutic drug monitoring. In this study, a simple and stable liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was attempted to be established and validated for pharmacokinetic studies of ripretinib and its metabolite DP-5439 and therapeutic drug monitoring in human plasma.

Theoretical study of the electronic and optical properties of a composite formed by the zeolite NaA and a magnetite cluster.

The electronic and optical properties of a composite created by introducing a magnetite cluster into NaA zeolite have been investigated in this work using DFT calculations. The results obtained indicate that the electronic and optical properties of the composite are enhanced because of the cluster. However, the properties exhibited by the cluster outside the zeolite differ from those it presents when it is part of the composite.

Lung cancer and risk of cardiovascular mortality.

Purpose: The aim of the present study was to investigate the cardiovascular mortality risk among lung cancer patients compared to the general population.

Methods: Using data from the National Cancer Institute's Surveillance, Epidemiology, and End Results program, we conducted a population-based cohort study including 278,418 lung cancer patients aged over 30 years between 1 January 1990 and 31 December 2020 as well as the general population. Poisson regression was employed to calculate incidence rate ratios (IRRs) for cardiovascular mortality.

Speech-Language Pathology Interventions in Pediatric Awake Brain Surgery: A Moroccan and Global Perspective.

Introduction Awake brain surgery (ABS) is a groundbreaking technique that not only enhances tumor resection but also preserves vital neurocognitive functions, particularly through advanced brain mapping. Despite its success in adults, ABS in pediatric patients remains significantly underexplored, especially concerning the role of speech-language pathology (SLP) in these procedures. This study addresses this gap by providing a thorough examination of SLP interventions in pediatric ABS across various university hospitals, including those in Morocco and internationally.

A methodological scoping review on EMG processing and synergy-based results in muscle synergy studies in Parkinson's disease.

Introduction: Parkinson's Disease is the second most common neurodegenerative disease in the world. It affects mainly people over 65 and the incidence increases with age. It is characterized by motor and non-motor symptoms and several clinical manifestations.

Differential regulation of apoptosis-related genes during long-term culture and differentiation of canine adipose-derived stem cells - a functional bioinformatical analysis.

Introduction: Stem cells derived from adipose tissue are gaining popularity in the field of regenerative medicine due to their adaptability and clinical potential. Their rapid growth, ability to differentiate, and easy extraction with minimal complications make adipose-derived stem cells (ADSCs) a promising option for many treatments, particularly those targeting bone-related diseases. This study analyzed gene expression in canine ADSCs subjected to long-term culture and osteogenic differentiation.

Barriers and enablers in the micronutrient powder supply chain: lessons from a process evaluation of a home fortification programme in Bangladesh.

Background: Bangladesh Rural Advancement Committee (BRAC), a leading non-governmental organization (NGO), implemented a large-scale Home Fortification (HF) with Micronutrient Powder (MNP) programme from 2013 to 2018 aimed to reduce undernutrition and iron deficiency anemia among children aged below 5 years old. An adequate and timely supply of MNP was crucial for successful implementation of the programme, but very few studies have documented implementers' MNP supply chain experiences. Therefore, this study aimed to explore the barriers and enablers in the MNP supply chain in Bangladesh.