Characterizing the pain score trajectories of hospitalized adult medical and surgical patients: a retrospective cohort study.

Pain care for hospitalized patients is often suboptimal. Representing pain scores as a graphical trajectory may provide insights into the understanding and treatment of pain. We describe a 1-year, retrospective, observational study to characterize pain trajectories of hospitalized adults during the first 48 hours after admission at an urban academic medical center.

Ziprosidone-Induced Transient Agranulocytosis; Delayed Onset of Cardiac Adverse Effects with Fingolimod; Telmisartan-Induced Myotoxicity; Severe Dilated Cardiomyopathy Induced by Adalimumab and Ustekinumab.

The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA's) MedWatch program (800-FDA-1088). If you have reported an interesting, preventable ADR to MedWatch, please consider sharing the account with our readers. Write to Dr.

Alteplase and Tenecteplase Confusion; Lack of E-Prescribing Interoperability Leads to Double Dosing; Accidental Overdoses Involving Fluorouracil Infusions.

These medication errors have occurred in health care facilities at least once. They will happen again-perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided.

Ranolazine-Induced Reversible T-Wave Inversions with Prolonged QTc Interval; Progressive Multifocal Leukoencephalopathy Linked to Fingolimod; Losartan-Induced Sprue-like Enteropathy; Nivolumab-Induced Psoriasiform Skin Eruption; Hepatitis B Reactivation with Hepatitis C Treatment with Simeprevir and Sofosbuvir.

The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA's) MED WATCH program (800-FDA-1088). If you have reported an interesting, preventable ADR to MED WATCH, please consider sharing the account with our readers. Write to Dr.

FDA Advise-ERR: Mefloquine-Not the Same as Malarone; Zoster Vaccine Is Not for the Immunosuppressed; TXA Mistaken as Tenecteplase; Guidelines for Adult IV Push Medications.

These medication errors have occurred in health care facilities at least once. They will happen again-perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided.

Pictograms for Safer Medication Management by Health Care Workers.

Background: Inherent risks are associated with the preparation and administration of medications. As such, a key aspect of medication safety is to ensure safe medication management practices.

Objective: To identify key medication safety issues and high-alert drug classes that might benefit from implementation of pictograms, for use by health care providers, to enhance medication administration safety.

Avoiding Medication Errors: Reducing Harm in Residents Using Oral Anticoagulants.

Medication errors involving oral anticoagulants have led to serious adverse events, including hemorrhage, treatment failures leading to thromboembolic events, and death. This article will highlight medication errors that may arise during the use of oral anticoagulants and provide risk-reduction strategies to address the potential for error and patient harm.

Cognitive tests predict real-world errors: the relationship between drug name confusion rates in laboratory-based memory and perception tests and corresponding error rates in large pharmacy chains.

Background: Drug name confusion is a common type of medication error and a persistent threat to patient safety. In the USA, roughly one per thousand prescriptions results in the wrong drug being filled, and most of these errors involve drug names that look or sound alike. Prior to approval, drug names undergo a variety of tests to assess their potential for confusability, but none of these preapproval tests has been shown to predict real-world error rates.

Key Vulnerabilities in the Surgical Environment: Container Mix-Ups and Syringe Swaps Do Not Confuse Idarucizumab with Idarubicin.

These medication errors have occurred in health care facilities at least once. They will happen again-perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided.

Atorvastatin-Induced Fixed Drug Eruption Clopidogrel-Induced Acute Hepatitis Bilateral Angle-Closure Glaucoma Induced by Chlorthalidone Risk of Anaphylactic Reactions with Intravenous Iron Products Zonisamide-Induced DRESS with Eosinophilic Pneumonia.

The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA's) MedWatch program (800-FDA-1088). If you have reported an interesting, preventable ADR to MedWatch, please consider sharing the account with our readers. Your report will be published anonymously unless otherwise requested.

Nonconvulsive Status Epilepticus in Elderly Patients Receiving SSRIs; Euglycemic Diabetic Ketoacidosis Associated with Canagliflozin Use in a Type 1 Diabetic Patient; Duloxetine-Induced Galactorrhea; Canagliflozin-Associated Severe Hypercalcemia and Hypernatremia; Vemurafenib-Induced Fanconi Syndrome.

The purpose of this feature is to heighten awareness of specific adverse drug reactions (ADRs), discuss methods of prevention, and promote reporting of ADRs to the US Food and Drug Administration's (FDA's) MedWatch program (800-FDA-1088). If you have reported an interesting, preventable ADR to MedWatch, please consider sharing the account with our readers. Write to Dr.

Oxycodone IV?; Eliminate Teaspoonfuls; Avoid Vitamin D Products Dosed and Measured in Drops.

These medication errors have occurred in health care facilities at least once. They will happen again-perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided.

Completeness of serious adverse drug event reports received by the US Food and Drug Administration in 2014.

Purpose: Adverse drug event reports to the US Food and Drug Administration (FDA) remain the primary tool for identifying serious drug adverse effects without adequate existing warnings. We assessed the completeness of reports the FDA received in 2014.

Methods: Serious adverse drug event reports were evaluated for whether they included age, gender, event date, and at least one medical term describing the event in computer excerpts.

Methylene Blue is a Monoamine Oxidase Inhibitor; Severe Harm and Death Associated with Low-Dose Methotrexate; Potentially Dangerous Mix-up between Cancer Drugs.

These medication errors have occurred in health care facilities at least once. They will happen again-perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided.